6LK2
| Crystal structure of Providencia alcalifaciens 3-dehydroquinate synthase (DHQS) in complex with Mg2+, NAD and chlorogenic acid | 分子名称: | (1R,3R,4S,5R)-3-[3-[3,4-bis(oxidanyl)phenyl]propanoyloxy]-1,4,5-tris(oxidanyl)cyclohexane-1-carboxylic acid, 1,2-ETHANEDIOL, 3-dehydroquinate synthase, ... | 著者 | Neetu, N, Katiki, M, Kumar, P. | 登録日 | 2019-12-17 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Structural and Biochemical Analyses Reveal that Chlorogenic Acid Inhibits the Shikimate Pathway. J.Bacteriol., 202, 2020
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8JFV
| Crystal structure of Catabolite repressor acivator from E. coli in complex with sulisobenzone | 分子名称: | 1,2-ETHANEDIOL, 2-methoxy-4-oxidanyl-5-(phenylcarbonyl)benzenesulfonic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Neetu, N, Sharma, M, Mahto, J.K, Kumar, P. | 登録日 | 2023-05-19 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Sulisobenzone is a potent inhibitor of the global transcription factor Cra. J.Struct.Biol., 215, 2023
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8JFF
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6LLA
| Crystal structure of Providencia alcalifaciens 3-dehydroquinate synthase (DHQS) in complex with Mg2+ and NAD | 分子名称: | 1,2-ETHANEDIOL, 3-dehydroquinate synthase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Neetu, N, Katiki, M, Kumar, P. | 登録日 | 2019-12-22 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural and Biochemical Analyses Reveal that Chlorogenic Acid Inhibits the Shikimate Pathway. J.Bacteriol., 202, 2020
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7DOB
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7DOA
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8TL8
| Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid | 分子名称: | GLYCOCHOLIC ACID, Protein sigma-NS | 著者 | Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N. | 登録日 | 2023-07-26 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories. Nat Commun, 15, 2024
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8DPQ
| Beta-lactamase CTX-M-14 N170A | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase | 著者 | Lu, S, Neetu, N, Palzkill, T. | 登録日 | 2022-07-15 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J.Biol.Chem., 299, 2023
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8ELB
| CTX-M-14 beta-lactamase mutant- N132A | 分子名称: | Beta-lactamase, DI(HYDROXYETHYL)ETHER | 著者 | Lu, S, Neetu, N, Palzkill, T. | 登録日 | 2022-09-23 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Mutagenesis and structural analysis reveal the CTX-M beta-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J.Biol.Chem., 299, 2023
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7F44
| Crystal structure of Moraxella catarrhalis enoyl-ACP-reductase (FabI) in complex with the cofactor NAD | 分子名称: | CALCIUM ION, Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL, ... | 著者 | Katiki, M, Neetu, N, Pratap, S, Kumar, P. | 登録日 | 2021-06-17 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Biochemical and structural basis for Moraxella catarrhalis enoyl-acyl carrier protein reductase (FabI) inhibition by triclosan and estradiol. Biochimie, 198, 2022
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7FCM
| Crystal structure of Moraxella catarrhalis enoyl-ACP-reductase (FabI) in complex with NAD and Triclosan | 分子名称: | CALCIUM ION, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Katiki, M, Neetu, N, Pratap, S, Kumar, P. | 登録日 | 2021-07-15 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Biochemical and structural basis for Moraxella catarrhalis enoyl-acyl carrier protein reductase (FabI) inhibition by triclosan and estradiol. Biochimie, 198, 2022
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8TMT
| Crystal structure of KPC-44 carbapenemase in complex with vaborbactam | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, LITHIUM ION, ... | 著者 | Sun, Z, Palzkill, T, Hu, L, Neetu, N, Lin, H, Sankaran, B, Wang, J, Prasad, B. | 登録日 | 2023-07-30 | 公開日 | 2023-12-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J.Biol.Chem., 300, 2023
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