1G1P
 
 | | NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus that Selectively Acts on Vertebrate Neuronal Na+ Channels | | 分子名称: | CONOTOXIN EVIA | | 著者 | Volpon, L, Lamthanh, H, Barbier, J, Gilles, N, Molgo, J, Menez, A, Lancelin, J.M. | | 登録日 | 2000-10-13 | | 公開日 | 2000-11-01 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus That Selectively Acts on Vertebrate Neuronal Na+ Channels.
J.Biol.Chem., 279, 2004
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1GC0
 | | CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA | | 分子名称: | METHIONINE GAMMA-LYASE | | 著者 | Motoshima, H, Inagaki, K, Kumasaka, T, Furuichi, M, Inoue, H, Tamura, T, Esaki, N, Soda, K, Tanaka, N, Yamamoto, M, Tanaka, H. | | 登録日 | 2000-07-06 | | 公開日 | 2002-05-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida.
J.Biochem., 128, 2000
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1UMB
 | | branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in holo-form | | 分子名称: | 2-oxo acid dehydrogenase alpha subunit, 2-oxo acid dehydrogenase beta subunit, MAGNESIUM ION, ... | | 著者 | Nakai, T, Nakagawa, N, Maoka, N, Masui, R, Kuramitsu, S, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-25 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography
J.Mol.Biol., 337, 2004
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1A7V
 | | CYTOCHROME C' FROM RHODOPSEUDOMONAS PALUSTRIS | | 分子名称: | CYTOCHROME C', PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Shibata, N, Iba, S, Misaki, S, Meyer, T.E, Bartsch, R.G, Cusanovich, M.A, Higuchi, Y, Yasuoka, N. | | 登録日 | 1998-03-18 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Basis for monomer stabilization in Rhodopseudomonas palustris cytochrome c' derived from the crystal structure.
J.Mol.Biol., 284, 1998
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1UM9
 | | branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in apo-form | | 分子名称: | 2-oxo acid dehydrogenase alpha subunit, 2-oxo acid dehydrogenase beta subunit, SULFATE ION | | 著者 | Nakai, T, Nakagawa, N, Maoka, N, Masui, R, Kuramitsu, S, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-25 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography
J.Mol.Biol., 337, 2004
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1UMC
 | | branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 with 4-methylpentanoate | | 分子名称: | 2-oxo acid dehydrogenase alpha subunit, 2-oxo acid dehydrogenase beta subunit, 4-METHYL VALERIC ACID, ... | | 著者 | Nakai, T, Nakagawa, N, Maoka, N, Masui, R, Kuramitsu, S, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-25 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography
J.Mol.Biol., 337, 2004
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1V9J
 | | Solution structure of a BolA-like protein from Mus musculus | | 分子名称: | BolA-like protein RIKEN cDNA 1110025L05 | | 著者 | Kasai, T, Inoue, M, Koshiba, S, Yabuki, T, Aoki, M, Nunokawa, E, Seki, E, Matsuda, T, Matsuda, N, Tomo, Y, Shirouzu, M, Terada, T, Obayashi, N, Hamana, H, Shinya, N, Tatsuguchi, A, Yasuda, S, Yoshida, M, Hirota, H, Matsuo, Y, Tani, K, Suzuki, H, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-01-26 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a BolA-like protein from Mus musculus
Protein Sci., 13, 2004
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1D9N
 | | SOLUTION STRUCTURE OF THE METHYL-CPG-BINDING DOMAIN OF THE METHYLATION-DEPENDENT TRANSCRIPTIONAL REPRESSOR MBD1/PCM1 | | 分子名称: | METHYL-CPG-BINDING PROTEIN MBD1 | | 著者 | Ohki, I, Shimotake, N, Fujita, N, Nakao, M, Shirakawa, M. | | 登録日 | 1999-10-28 | | 公開日 | 2000-10-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1.
EMBO J., 18, 1999
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5LZL
 | | Pyrobaculum calidifontis 5-aminolaevulinic acid dehydratase | | 分子名称: | Delta-aminolevulinic acid dehydratase, ZINC ION | | 著者 | Azim, N, Erskine, P.T, Guo, J, Cooper, J.B. | | 登録日 | 2016-09-30 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | | 主引用文献 | Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
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1ITK
 | | Crystal structure of catalase-peroxidase from Haloarcula marismortui | | 分子名称: | CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | | 著者 | Yamada, Y, Fujiwara, T, Sato, T, Igarashi, N, Tanaka, N. | | 登録日 | 2002-01-18 | | 公開日 | 2002-08-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The 2.0 A crystal structure of catalase-peroxidase from Haloarcula marismortui.
Nat.Struct.Biol., 9, 2002
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1IW8
 | | Crystal Structure of a mutant of acid phosphatase from Escherichia blattae (G74D/I153T) | | 分子名称: | SULFATE ION, acid phosphatase | | 著者 | Ishikawa, K, Mihara, Y, Shimba, N, Ohtsu, N, Kawasaki, H, Suzuki, E, Asano, Y. | | 登録日 | 2002-04-22 | | 公開日 | 2002-09-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enhancement of nucleoside phosphorylation activity in an acid phosphatase
PROTEIN ENG., 15, 2002
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1J2T
 | | Creatininase Mn | | 分子名称: | MANGANESE (II) ION, SULFATE ION, ZINC ION, ... | | 著者 | Yoshimoto, T, Tanaka, N, Kanada, N, Inoue, T, Nakajima, Y, Haratake, M, Nakamura, K.T, Xu, Y, Ito, K. | | 登録日 | 2003-01-11 | | 公開日 | 2004-01-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of creatininase reveal the substrate binding site and provide an insight into the catalytic mechanism
J.Mol.Biol., 337, 2004
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6ZUQ
 | | Crystal structure of the effector Ecp11-1 from Fulvia fulva | | 分子名称: | Extracellular protein 11-1, GLYCEROL, ZINC ION | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-07-23 | | 公開日 | 2021-08-04 | | 最終更新日 | 2022-07-27 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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6ZUS
 | | Crystal structure of the effector Ecp11-1 from Fulvia fulva | | 分子名称: | DI(HYDROXYETHYL)ETHER, Extracellular protein 11-1, GLYCEROL, ... | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-07-23 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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1IXL
 | | Crystal structure of uncharacterized protein PH1136 from Pyrococcus horikoshii | | 分子名称: | hypothetical protein PH1136 | | 著者 | Tajika, Y, Sakai, N, Tanaka, Y, Yao, M, Watanabe, N, Tanaka, I. | | 登録日 | 2002-06-27 | | 公開日 | 2003-09-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Crystal structure of conserved protein PH1136 from Pyrococcus horikoshii.
Proteins, 55, 2004
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1J31
 | | Crystal Structure of Hypothetical Protein PH0642 from Pyrococcus horikoshii | | 分子名称: | ACETATE ION, Hypothetical protein PH0642 | | 著者 | Sakai, N, Tajika, Y, Yao, M, Watanabe, N, Tanaka, I. | | 登録日 | 2003-01-16 | | 公開日 | 2004-03-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of hypothetical protein PH0642 from Pyrococcus horikoshii at 1.6A resolution.
Proteins, 57, 2004
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1IWB
 | | Crystal structure of diol dehydratase | | 分子名称: | COBALAMIN, DIOL DEHYDRATASE alpha chain, DIOL DEHYDRATASE beta chain, ... | | 著者 | Shibata, N, Masuda, J, Morimoto, Y, Yasuoka, N, Toraya, T. | | 登録日 | 2002-05-01 | | 公開日 | 2003-05-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Substrate-induced conformational change of a coenzyme B12-dependent enzyme: crystal structure of the substrate-free form of diol dehydratase
Biochemistry, 41, 2002
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7AD5
 | | Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans | | 分子名称: | ACETATE ION, Avirulence protein LmJ1, GLYCEROL, ... | | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | | 登録日 | 2020-09-14 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
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1J0F
 | | Solution Structure of the SH3 Domain Binding Glutamic Acid-rich Protein Like 3 | | 分子名称: | SH3 domain-binding glutamic acid-rich-like protein 3 | | 著者 | Miyamoto, K, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-11-12 | | 公開日 | 2003-12-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the SH3 Domain Binding Glutamic Acid-rich Protein Like 3
To be Published
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8UDV
 | | The X-RAY co-crystal structure of human FGFR3 V555M and Compound 17 | | 分子名称: | 1,2-ETHANEDIOL, 3-[(6-chloro-1-cyclopropyl-1H-benzimidazol-5-yl)ethynyl]-1-[(3S,5S)-5-(methoxymethyl)-1-(prop-2-enoyl)pyrrolidin-3-yl]-5-(methylamino)-1H-pyrazole-4-carboxamide, Fibroblast growth factor receptor 3, ... | | 著者 | Tyhonas, J.S, Arnold, L.D, Cox, J, Franovic, A, Gardiner, E, Grandinetti, K, Kania, R, Kanouni, T, Lardy, M, Li, C, Martin, E.S, Miller, N, Mohan, A, Murphy, E.A, Perez, M, Soroceanu, L, Timple, N, Uryu, S, Womble, S, Kaldor, S.W. | | 登録日 | 2023-09-29 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.348 Å) | | 主引用文献 | Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations.
J.Med.Chem., 67, 2024
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1P83
 | | NMR STRUCTURE OF 1-25 FRAGMENT OF MYCOBACTERIUM TUBERCULOSIS CPN10 | | 分子名称: | 10 kDa chaperonin | | 著者 | Ciutti, A, Spiga, O, Giannozzi, E, Scarselli, M, Di Maro, D, Calamandrei, D, Niccolai, N, Bernini, A. | | 登録日 | 2003-05-06 | | 公開日 | 2003-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of 1-25 fragment of Cpn10 from Mycobacterium Tuberculosis
To be Published
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8RPB
 | | Structure of S79 Fab in complex with IgV domain of human PD-L1 | | 分子名称: | CHLORIDE ION, GLYCEROL, Programmed cell death 1 ligand 1, ... | | 著者 | Svensson, A, Kelpsas, V, Laursen, M, Rose, N. | | 登録日 | 2024-01-15 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1.
Mabs, 16, 2024
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8V2F
 | | Crystal structure of IRAK4 kinase domain with compound 9 | | 分子名称: | CHLORIDE ION, GLYCEROL, Interleukin-1 receptor-associated kinase 4, ... | | 著者 | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | | 登録日 | 2023-11-22 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma.
J.Med.Chem., 67, 2024
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8V1O
 | | Crystal structure of IRAK4 kinase domain with compound 4 | | 分子名称: | CHLORIDE ION, GLYCEROL, Interleukin-1 receptor-associated kinase 4, ... | | 著者 | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | | 登録日 | 2023-11-21 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma.
J.Med.Chem., 67, 2024
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8V2L
 | | Crystal structure of IRAK4 kinase domain with compound 8 | | 分子名称: | 1,2-ETHANEDIOL, Interleukin-1 receptor-associated kinase 4, N-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | | 著者 | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | | 登録日 | 2023-11-22 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma.
J.Med.Chem., 67, 2024
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