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PDB: 5 件

8VKA
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BU of 8vka by Molmil
Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 9c
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Fenwick, M.K, Staker, B.L, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-01-08
公開日2024-07-17
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Exploring Subsite Selectivity within Plasmodium vivax N -Myristoyltransferase Using Pyrazole-Derived Inhibitors.
J.Med.Chem., 67, 2024
8VKB
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BU of 8vkb by Molmil
Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 10b
分子名称: CHLORIDE ION, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase, ...
著者Fenwick, M.K, Staker, B.L, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-01-08
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Exploring Subsite Selectivity within Plasmodium vivax N -Myristoyltransferase Using Pyrazole-Derived Inhibitors.
J.Med.Chem., 67, 2024
8FBP
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BU of 8fbp by Molmil
Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation
分子名称: Glutamine synthetase
著者Phan, I.Q, Staker, B, Shek, R, Moser, T.H, Evans, J.E, van Voorhis, W.C, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-11-29
公開日2024-02-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Glutamine synthetase from Pseudomonas aeruginosa, filament double-unit in compressed conformation
To Be Published
3GMT
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BU of 3gmt by Molmil
Crystal structure of adenylate kinase from burkholderia pseudomallei
分子名称: Adenylate kinase, SULFATE ION
著者Abendroth, J, Staker, B.L, Robinson, H, Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W, Stacy, R, Myler, P.J, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-03-15
公開日2009-06-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state.
Biochem.Biophys.Res.Commun., 394, 2010
8FBQ
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BU of 8fbq by Molmil
Crystal structure of Plasmodium vivax glycylpeptide N-tetradecanoyltransferase (N-myristoyltransferase, NMT) bound to myristoyl-CoA and inhibitor 12b
分子名称: 1-[(3M)-3-{3-[2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethoxy]pyridin-2-yl}phenyl]piperazine, ACETATE ION, CHLORIDE ION, ...
著者Fenwick, M.K, Staker, B.L, Lovell, S.W, Phan, I.Q, Early, J, Myler, P.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-11-29
公開日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts.
Nat Commun, 14, 2023

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件を2024-11-06に公開中

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