6J88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j88 by Molmil](/molmil-images/mine/6j88) | Crystal structure of HinD with benzo[b]thiophen analog | Descriptor: | N-[(2S)-1-(1-benzothiophen-3-yl)-3-hydroxypropan-2-yl]-N~2~-methyl-L-valinamide, Nocardicin N-oxygenase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Fei, H, Mori, T, Abe, I. | Deposit date: | 2019-01-18 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
|
|
6J85
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j85 by Molmil](/molmil-images/mine/6j85) | Crystal structure of HinD apo | Descriptor: | Nocardicin N-oxygenase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Fei, H, Mori, T, Abe, I. | Deposit date: | 2019-01-18 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
|
|
6J86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j86 by Molmil](/molmil-images/mine/6j86) | Crystal structure of HinD with NMFT | Descriptor: | N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]-Nalpha-methyl-L-phenylalaninamide, Nocardicin N-oxygenase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Fei, H, Mori, T, Abe, I. | Deposit date: | 2019-01-18 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
|
|
6J83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j83 by Molmil](/molmil-images/mine/6j83) | Crystal structure of TleB with NMVT | Descriptor: | Cytochrome P-450, N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]-N~2~-methyl-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Fei, H, Mori, T, Abe, I. | Deposit date: | 2019-01-18 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
|
|
6J84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j84 by Molmil](/molmil-images/mine/6j84) | Crystal structure of TleB with hydroxyl analog | Descriptor: | (2S)-2-hydroxy-N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]-3-methylbutanamide, Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Nakamura, H, Mori, T, Abe, I. | Deposit date: | 2019-01-18 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
|
|
6J87
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j87 by Molmil](/molmil-images/mine/6j87) | Crystal structure of HinD with NMFT and NO | Descriptor: | N-[(2S)-1-hydroxy-3-(1H-indol-3-yl)propan-2-yl]-Nalpha-methyl-L-phenylalaninamide, NITRIC OXIDE, Nocardicin N-oxygenase, ... | Authors: | Fei, H, Mori, T, Abe, I. | Deposit date: | 2019-01-18 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular basis for the P450-catalyzed C-N bond formation in indolactam biosynthesis. Nat.Chem.Biol., 15, 2019
|
|
1L5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1l5b by Molmil](/molmil-images/mine/1l5b) | DOMAIN-SWAPPED CYANOVIRIN-N DIMER | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, cyanovirin-N | Authors: | Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. | Deposit date: | 2002-03-06 | Release date: | 2002-05-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure, 10, 2002
|
|
1L5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1l5e by Molmil](/molmil-images/mine/1l5e) | The domain-swapped dimer of CV-N in solution | Descriptor: | Cyanovirin-N | Authors: | Barrientos, L.G, Louis, J.M, Botos, I, Mori, T, Han, Z, O'Keefe, B.R, Boyd, M.R, Wlodawer, A, Gronenborn, A.M. | Deposit date: | 2002-03-06 | Release date: | 2002-06-05 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure, 10, 2002
|
|
1LOM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lom by Molmil](/molmil-images/mine/1lom) | CYANOVIRIN-N DOUBLE MUTANT P51S S52P | Descriptor: | CALCIUM ION, Cyanovirin-N, SULFATE ION | Authors: | Botos, I, Mori, T, Cartner, L.K, Boyd, M.R, Wlodawer, A. | Deposit date: | 2002-05-06 | Release date: | 2002-06-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Domain-swapped structure of a mutant of cyanovirin-N. Biochem.Biophys.Res.Commun., 294, 2002
|
|
8IYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iyf by Molmil](/molmil-images/mine/8iyf) | |
8IYE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iye by Molmil](/molmil-images/mine/8iye) | |
7VBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vbq by Molmil](/molmil-images/mine/7vbq) | Heterodimer structure of Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxIJ | Descriptor: | FE (III) ION, Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxI, Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxJ, ... | Authors: | Li, X, Awakawa, T, Mori, T, Abe, I. | Deposit date: | 2021-09-01 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis. J.Am.Chem.Soc., 143, 2021
|
|
7VBR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vbr by Molmil](/molmil-images/mine/7vbr) | |
7BWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bww by Molmil](/molmil-images/mine/7bww) | Structure of the engineered metallo-Diels-Alderase DA7 W16S | Descriptor: | ACETIC ACID, BENZOIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Basler, S, Mori, T, Hilvert, D. | Deposit date: | 2020-04-16 | Release date: | 2021-04-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold. Nat.Chem., 13, 2021
|
|
6LCC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lcc by Molmil](/molmil-images/mine/6lcc) | |
8JMR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jmr by Molmil](/molmil-images/mine/8jmr) | Crystal structure of hinokiresinol synthase in complex with 1,7-bis(4-hydroxyphenyl)hepta-1,6-dien-3-one | Descriptor: | 1,7-bis(4-hydroxyphenyl)hepta-1,6-dien-3-one, Hinokiresinol synthase alpha subunit, Hinokiresinol synthase beta subunit, ... | Authors: | Ding, Y, Ushimaru, R, Mori, T, Abe, I. | Deposit date: | 2023-06-05 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Mechanistic Insights into the C-C Bond-Forming Rearrangement Reaction Catalyzed by Heterodimeric Hinokiresinol Synthase. J.Am.Chem.Soc., 145, 2023
|
|
8JMQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jmq by Molmil](/molmil-images/mine/8jmq) | Crystal structure of hinokiresinol synthase | Descriptor: | Hinokiresinol synthase alpha subunit, Hinokiresinol synthase beta subunit | Authors: | Ding, Y, Ushimaru, R, Mori, T, Abe, I. | Deposit date: | 2023-06-05 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Mechanistic Insights into the C-C Bond-Forming Rearrangement Reaction Catalyzed by Heterodimeric Hinokiresinol Synthase. J.Am.Chem.Soc., 145, 2023
|
|
8JMS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jms by Molmil](/molmil-images/mine/8jms) | |
4ZKF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zkf by Molmil](/molmil-images/mine/4zkf) | Crystal structure of human phosphodiesterase 12 | Descriptor: | 2',5'-phosphodiesterase 12, MAGNESIUM ION | Authors: | Kim, S.Y, Kohno, T, Mori, T, Kitano, K, Hakoshima, T. | Deposit date: | 2015-04-30 | Release date: | 2015-06-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of human phosphodiesterase To Be Published
|
|
5B6B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b6b by Molmil](/molmil-images/mine/5b6b) | Complex of LATS1 and phosphomimetic MOB1b | Descriptor: | CHLORIDE ION, MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ... | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | Deposit date: | 2016-05-26 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.536 Å) | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway Sci Rep, 6, 2016
|
|
5B5W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b5w by Molmil](/molmil-images/mine/5b5w) | Crystal structure of MOB1-LATS1 NTR domain complex | Descriptor: | MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ZINC ION | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | Deposit date: | 2016-05-24 | Release date: | 2016-07-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.957 Å) | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway Sci Rep, 6, 2016
|
|
5B5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b5v by Molmil](/molmil-images/mine/5b5v) | Structure of full-length MOB1b | Descriptor: | CHLORIDE ION, MOB kinase activator 1B, ZINC ION | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | Deposit date: | 2016-05-24 | Release date: | 2016-07-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.193 Å) | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway Sci Rep, 6, 2016
|
|
8J5F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j5f by Molmil](/molmil-images/mine/8j5f) | |
8J5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j5g by Molmil](/molmil-images/mine/8j5g) | Crystal structure of kinase AbmG in complex with 4'-hydroxy-4'-thiocytidine 5'-diphosphate | Descriptor: | Deoxyadenosine/deoxycytidine kinase, [(2~{S},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-2-(hydroxymethyl)-3,4-bis(oxidanyl)thiolan-2-yl] phosphono hydrogen phosphate | Authors: | Ushimaru, R, Mori, T, Liu, H.-w, Abe, I. | Deposit date: | 2023-04-22 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of kinase AbmG in complex with 4'-hydroxy-4'-thiocytidine 5'-diphosphate To Be Published
|
|
8J5E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j5e by Molmil](/molmil-images/mine/8j5e) | Crystal structure of kinase AbmG in complex with 4'-thiocytidine | Descriptor: | 4-azanyl-1-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)thiolan-2-yl]pyrimidin-2-one, Deoxyadenosine/deoxycytidine kinase | Authors: | Ushimaru, R, Mori, T, Liu, H.-w, Abe, I. | Deposit date: | 2023-04-22 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of kinase AbmG in complex with 4'-thiocytidine To Be Published
|
|