1CH4
 
 | | MODULE-SUBSTITUTED CHIMERA HEMOGLOBIN BETA-ALPHA (F133V) | | 分子名称: | CARBON MONOXIDE, MODULE-SUBSTITUTED CHIMERA HEMOGLOBIN BETA-ALPHA, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Shirai, T, Fujikake, M, Yamane, T, Inaba, K, Ishimori, K, Morishima, I. | | 登録日 | 1998-06-11 | | 公開日 | 1999-04-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a protein with an artificial exon-shuffling, module M4-substituted chimera hemoglobin beta alpha, at 2.5 A resolution.
J.Mol.Biol., 287, 1999
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1T87
 | | Crystal Structure of the Ferrous CO-bound Cytochrome P450cam (C334A) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CARBON MONOXIDE, ... | | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | | 登録日 | 2004-05-11 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
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1T88
 | | Crystal Structure of the Ferrous Cytochrome P450cam (C334A) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | | 登録日 | 2004-05-11 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
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1X2I
 | | Crystal Structure Of Archaeal Xpf/Mus81 Homolog, Hef From Pyrococcus Furiosus, Helix-hairpin-helix Domain | | 分子名称: | Hef helicase/nuclease | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2005-04-24 | | 公開日 | 2005-09-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and Functional Analyses of an Archaeal XPF/Rad1/Mus81 Nuclease: Asymmetric DNA Binding and Cleavage Mechanisms
STRUCTURE, 13, 2005
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8SLJ
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1T85
 | | Crystal Structure of the Ferrous CO-bound Cytochrome P450cam Mutant (L358P/C334A) | | 分子名称: | CAMPHOR, CARBON MONOXIDE, Cytochrome P450-cam, ... | | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | | 登録日 | 2004-05-11 | | 公開日 | 2004-06-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
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1T86
 | | Crystal Structure of the Ferrous Cytochrome P450cam Mutant (L358P/C334A) | | 分子名称: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | | 著者 | Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. | | 登録日 | 2004-05-11 | | 公開日 | 2004-05-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
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1ENJ
 | | CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS | | 分子名称: | ENDONUCLEASE V | | 著者 | Vassylyev, D.G, Ariyoshi, M, Matsumoto, O, Katayanagi, K, Ohtsuka, E, Morikawa, K. | | 登録日 | 1994-08-08 | | 公開日 | 1994-10-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
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1J1I
 | | Crystal structure of a His-tagged Serine Hydrolase Involved in the Carbazole Degradation (CarC enzyme) | | 分子名称: | meta cleavage compound hydrolase | | 著者 | Habe, H, Morii, K, Fushinobu, S, Nam, J.W, Ayabe, Y, Yoshida, T, Wakagi, T, Yamane, H, Nojiri, H, Omori, T. | | 登録日 | 2002-12-05 | | 公開日 | 2003-06-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structure of a histidine-tagged serine hydrolase involved in the carbazole degradation (CarC enzyme).
Biochem.Biophys.Res.Commun., 303, 2003
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1POY
 | | SPERMIDINE/PUTRESCINE-BINDING PROTEIN COMPLEXED WITH SPERMIDINE (DIMER FORM) | | 分子名称: | SPERMIDINE, SPERMIDINE/PUTRESCINE-BINDING PROTEIN | | 著者 | Sugiyama, S, Vassylyev, D.G, Matsushima, M, Morikawa, K. | | 登録日 | 1996-02-02 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli.
J.Biol.Chem., 271, 1996
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1POT
 | | SPERMIDINE/PUTRESCINE-BINDING PROTEIN COMPLEXED WITH SPERMIDINE (MONOMER FORM) | | 分子名称: | SPERMIDINE, SPERMIDINE/PUTRESCINE-BINDING PROTEIN | | 著者 | Sugiyama, S, Maenaka, K, Matsushima, M, Morikawa, K. | | 登録日 | 1996-02-02 | | 公開日 | 1996-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The 1.8-A X-ray structure of the Escherichia coli PotD protein complexed with spermidine and the mechanism of polyamine binding.
Protein Sci., 5, 1996
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1GOB
 | | COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION | | 分子名称: | RIBONUCLEASE H | | 著者 | Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S. | | 登録日 | 1993-05-10 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
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1GOC
 | | COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION | | 分子名称: | RIBONUCLEASE H | | 著者 | Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S. | | 登録日 | 1993-05-10 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
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1GOA
 | | COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION | | 分子名称: | RIBONUCLEASE H | | 著者 | Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S. | | 登録日 | 1993-05-10 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
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2FFN
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1IPI
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2EWK
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3M0V
 | | Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant S329L in complex with L-rhamnose | | 分子名称: | L-RHAMNOSE, L-rhamnose isomerase, MANGANESE (II) ION | | 著者 | Yoshida, H, Takeda, K, Izumori, K, Kamitori, S. | | 登録日 | 2010-03-03 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Elucidation of the role of Ser329 and the C-terminal region in the catalytic activity of Pseudomonas stutzeri L-rhamnose isomerase
Protein Eng.Des.Sel., 23, 2010
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1J25
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Mn cocrystal | | 分子名称: | ATP-dependent RNA helicase, putative, MANGANESE (II) ION | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2002-12-25 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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3VI8
 | | Human PPAR alpha ligand binding domain in complex with a synthetic agonist APHM13 | | 分子名称: | (2S)-2-(4-methoxy-3-{[(pyren-1-ylcarbonyl)amino]methyl}benzyl)butanoic acid, Peroxisome proliferator-activated receptor alpha | | 著者 | Oyama, T, Miyachi, H, Morikawa, K. | | 登録日 | 2011-09-25 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype
J.Med.Chem., 55, 2012
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1J24
 | | Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Ca cocrystal | | 分子名称: | ATP-dependent RNA helicase, putative, CALCIUM ION | | 著者 | Nishino, T, Komori, K, Ishino, Y, Morikawa, K. | | 登録日 | 2002-12-25 | | 公開日 | 2003-04-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | X-Ray and Biochemical Anatomy of an Archaeal XPF/Rad1/Mus81 Family Nuclease. Similarity between Its Endonuclease Domain and Restriction Enzymes
Structure, 11, 2003
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5J8L
 | | Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with 1-deoxy L-tagatose, using a crystal grown in microgravity | | 分子名称: | 1-deoxy-L-tagatose, 1-deoxy-beta-L-tagatopyranose, D-tagatose 3-epimerase, ... | | 著者 | Yoshida, H, Yoshihara, A, Izumori, K, Kamitori, S. | | 登録日 | 2016-04-08 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates
Appl. Microbiol. Biotechnol., 100, 2016
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7FBW
 | | Acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis | | 分子名称: | NICKEL (II) ION, Predicted xylanase/chitin deacetylase | | 著者 | Sasamoto, K, Himiyama, T, Moriyoshi, K, Ohmoto, T, Uegaki, K, Nishiya, Y, Nakamura, T. | | 登録日 | 2021-07-13 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis.
Acta Crystallogr.,Sect.F, 77, 2021
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1FUT
 | | CRYSTAL STRUCTURES OF RIBONUCLEASE F1 OF FUSARIUM MONILIFORME IN ITS FREE FORM AND IN COMPLEX WITH 2'GMP | | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE F1 | | 著者 | Katayanagi, K, Vassylyev, D.G, Ishikawa, K, Morikawa, K. | | 登録日 | 1993-01-18 | | 公開日 | 1993-10-31 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2'GMP.
J.Mol.Biol., 230, 1993
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6JT4
 | | Crystal Structure of BACE1 in complex with N-{3-[(4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide | | 分子名称: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | | 著者 | Anan, K, Iso, Y, Oguma, T, Nakahara, K, Suzuki, S, Yamamoto, T, Matsuoka, E, Ito, H, Sakaguchi, G, Ando, S, Morimoto, K, Kanegawa, N, Kido, Y, Kawachi, T, Fukushima, T, Teisman, A, Urmaliya, V, Dhuyvetter, D, Borghys, H, Austin, N, Bergh, A.V.D, Verboven, P, Bischoff, F, Gijsen, H.J.M, Yamano, Y, Kusakabe, K.I. | | 登録日 | 2019-04-08 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Trifluoromethyl Dihydrothiazine-Based beta-Secretase (BACE1) Inhibitors with Robust Central beta-Amyloid Reduction and Minimal Covalent Binding Burden.
Chemmedchem, 14, 2019
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