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PDB: 21 件

4CNJ
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L-Aminoacetone oxidase from Streptococcus oligofermentans belongs to a new 3-domain family of bacterial flavoproteins
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-AMINO ACID OXIDASE
著者Molla, G, Nardini, M, Motta, P, D'Arrigo, P, Bolognesi, M, Pollegioni, L.
登録日2014-01-23
公開日2014-10-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Aminoacetone Oxidase from Streptococcus Oligofermentas Belongs to a New Three-Domain Family of Bacterial Flavoproteins.
Biochem.J., 464, 2014
4CNK
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L-Aminoacetone oxidase from Streptococcus oligofermentans belongs to a new 3-domain family of bacterial flavoproteins
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-AMINO ACID OXIDASE, ...
著者Molla, G, Nardini, M, Motta, P, D'Arrigo, P, Bolognesi, M, Pollegioni, L.
登録日2014-01-23
公開日2014-10-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Aminoacetone Oxidase from Streptococcus Oligofermentas Belongs to a New Three-Domain Family of Bacterial Flavoproteins.
Biochem.J., 464, 2014
3ZNN
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IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN
分子名称: 4H-THIENO[3,2-B]PYROLE-5-CARBOXYLIC ACID, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H.
登録日2013-02-15
公開日2013-05-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
J.Med.Chem., 56, 2013
3ZNP
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IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN
分子名称: 3-HYDROXY-2H-CHROMEN-2-ONE, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H.
登録日2013-02-15
公開日2013-05-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
J.Med.Chem., 56, 2013
3ZNO
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IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN
分子名称: 4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H.
登録日2013-02-15
公開日2013-05-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
J.Med.Chem., 56, 2013
3ZNQ
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IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN
分子名称: 3-PHENETHYL-4H-FURO[3,2-B]PYRROLE-5-CARBOXYLIC ACID, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H.
登録日2013-02-15
公開日2013-05-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
J.Med.Chem., 56, 2013
5FJN
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Structure of L-Amino acid deaminase from Proteus myxofaciens in complex with anthranilate
分子名称: 2-AMINOBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, L-AMINO ACID DEAMINASE
著者Motta, P, Molla, G, Pollegioni, L, Nardini, M.
登録日2015-10-11
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure-Function Relationships in L-Amino Acid Deaminase, a Flavoprotein Belonging to a Novel Class of Biotechnologically Relevant Enzymes
J.Biol.Chem., 291, 2016
1RYI
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STRUCTURE OF GLYCINE OXIDASE WITH BOUND INHIBITOR GLYCOLATE
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE OXIDASE, GLYCOLIC ACID
著者Moertl, M, Diederichs, K, Welte, W, Pollegioni, L, Molla, G, Motteran, L, Andriolo, G, Pilone, M.S.
登録日2003-12-22
公開日2005-02-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-function correlation in glycine oxidase from Bacillus subtilis
J.Biol.Chem., 279, 2004
3IF9
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Crystal structure of Glycine Oxidase G51S/A54R/H244A mutant in complex with inhibitor glycolate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCOLIC ACID, Glycine oxidase
著者Pedotti, M, Rosini, E, Molla, G, Moschetti, T, Vallone, B, Savino, C, Pollegioni, L.
登録日2009-07-24
公開日2009-10-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Glyphosate resistance by engineering the flavoenzyme glycine oxidase.
J.Biol.Chem., 284, 2009
5FJM
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Structure of L-Amino acid deaminase from Proteus myxofaciens
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-AMINO ACID DEAMINASE
著者Motta, P, Molla, G, Pollegioni, L, Nardini, M.
登録日2015-10-11
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Function Relationships in L-Amino Acid Deaminase, a Flavoprotein Belonging to a Novel Class of Biotechnologically Relevant Enzymes
J.Biol.Chem., 291, 2016
4HST
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Crystal structure of a double mutant of a class III engineered cephalosporin acylase
分子名称: 5,5-dihydroxy-L-norvaline, glutaryl-7-aminocephalosporanic acid acylase alpha chain, glutaryl-7-aminocephalosporanic acid acylase beta chain
著者Vrielink, A, Golden, E, Patterson, R, Tie, W.J, Anandan, A, Flematti, G, Molla, G, Rosini, E, Pollegioni, L.
登録日2012-10-30
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.571 Å)
主引用文献Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity.
Biochem.J., 451, 2013
4HSR
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Crystal Structure of a class III engineered cephalosporin acylase
分子名称: 5,5-dihydroxy-L-norvaline, glutaryl-7-aminocephalosporanic acid acylase alpha chain, glutaryl-7-aminocephalosporanic acid acylase beta chain
著者Vrielink, A, Golden, E, Patterson, R, Tie, W.J, Anandan, A, Flematti, G, Molla, G, Rosini, E, Pollegioni, L.
登録日2012-10-30
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity.
Biochem.J., 451, 2013
1C0L
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D-AMINO ACID OXIDASE: STRUCTURE OF SUBSTRATE COMPLEXES AT VERY HIGH RESOLUTION REVEAL THE CHEMICAL REACTTION MECHANISM OF FLAVIN DEHYDROGENATION
分子名称: D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, TRIFLUOROALANINE
著者Umhau, S, Molla, G, Diederichs, K, Pilone, M.S, Ghisla, S, Welte, W.
登録日1999-07-16
公開日2000-11-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1C0I
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CRYSTAL STRUCTURE OF D-AMINO ACID OXIDASE IN COMPLEX WITH TWO ANTHRANYLATE MOLECULES
分子名称: 2-AMINOBENZOIC ACID, D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Pollegioni, L, Diederichs, K, Molla, G, Umhau, S, Welte, W, Ghisla, S, Pilone, M.S.
登録日1999-07-16
公開日2002-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Yeast d-amino Acid oxidase: structural basis of its catalytic properties
J.Mol.Biol., 324, 2002
1C0K
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CRYSTAL STRUCTURE ANALYSIS OF D-AMINO ACID OXIDASE IN COMPLEX WITH L-LACTATE
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, PROTEIN (D-AMINO ACID OXIDASE)
著者Umhau, S, Molla, G, Diederichs, K, Pilone, M.S, Ghisla, S, Welte, W, Pollegioni, L.
登録日1999-07-16
公開日2000-11-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation.
Proc.Natl.Acad.Sci.USA, 97, 2000
1C0P
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D-AMINO ACIC OXIDASE IN COMPLEX WITH D-ALANINE AND A PARTIALLY OCCUPIED BIATOMIC SPECIES
分子名称: D-ALANINE, D-AMINO ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Umhau, S, Pollegioni, L, Molla, G, Diederichs, K, Welte, W, Pilone, S.M, Ghisla, S.
登録日1999-07-19
公開日2000-11-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation.
Proc.Natl.Acad.Sci.USA, 97, 2000
9ENJ
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L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with L-glutamate
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLUTAMIC ACID, L-amino acid oxidase 4, ...
著者Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H.
登録日2024-03-13
公開日2024-08-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and enzyme engineering of the broad substrate spectrum l-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum.
Febs Lett., 598, 2024
9ENK
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L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with L-phenylalanine
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-amino acid oxidase 4, PHENYLALANINE, ...
著者Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H.
登録日2024-03-13
公開日2024-08-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure and enzyme engineering of the broad substrate spectrum l-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum.
Febs Lett., 598, 2024
9ENI
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L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with L-glutamine
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLUTAMINE, L-amino acid oxidase 4, ...
著者Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H.
登録日2024-03-13
公開日2024-08-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and enzyme engineering of the broad substrate spectrum l-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum.
Febs Lett., 598, 2024
9ENN
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L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum in complex with N-epsilon-acetyl-L-lysine
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, L-amino acid oxidase 4, N(6)-ACETYLLYSINE, ...
著者Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H.
登録日2024-03-13
公開日2024-08-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and enzyme engineering of the broad substrate spectrum l-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum.
Febs Lett., 598, 2024
9ENH
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L-amino acid oxidase 4 (HcLAAO4) from the fungus Hebeloma cylindrosporum
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase 4, S-1,2-PROPANEDIOL, ...
著者Gilzer, D, Koopmeiners, S, Fischer von Mollard, G, Niemann, H.H.
登録日2024-03-13
公開日2024-08-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and enzyme engineering of the broad substrate spectrum l-amino acid oxidase 4 from the fungus Hebeloma cylindrosporum.
Febs Lett., 598, 2024

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