5QCI
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![BU of 5qci by Molmil](/molmil-images/mine/5qci) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | Cathepsin S, GLYCEROL, N-benzyl-1-{5-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]-2-methoxyphenyl}methanamine, ... | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (2.179 Å) | 主引用文献 | Crystal structure of human Cathepsin-S with bound ligand To be published
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5QBX
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![BU of 5qbx by Molmil](/molmil-images/mine/5qbx) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | (2S)-1-[4-(2-methoxyphenyl)piperidin-1-yl]-3-{3-[3-{[2-(piperidin-1-yl)ethyl]sulfanyl}-4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propan-2-ol, Cathepsin S | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of human Cathepsin-S with bound ligand To be published
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5QCE
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![BU of 5qce by Molmil](/molmil-images/mine/5qce) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | Cathepsin S, N-benzyl-1-{2-chloro-5-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]phenyl}methanamine | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Crystal structure of human Cathepsin-S with bound ligand To be published
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5QCF
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![BU of 5qcf by Molmil](/molmil-images/mine/5qcf) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | Cathepsin S, GLYCEROL, N-benzyl-1-{2-chloro-5-[(2-chloro-5-{5-(methylsulfonyl)-1-[3-(morpholin-4-yl)propyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl}phenyl)ethynyl]phenyl}methanamine, ... | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of human Cathepsin-S with bound ligand To be published
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5QC4
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![BU of 5qc4 by Molmil](/molmil-images/mine/5qc4) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | 2-[5-[5-ethanoyl-1-[(2~{R})-2-oxidanyl-3-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]propyl]-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-3-yl]-2-(trifluoromethyl)phenyl]sulfanyl-1-pyrrolidin-1-yl-ethanone, Cathepsin S | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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5QBV
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![BU of 5qbv by Molmil](/molmil-images/mine/5qbv) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | Cathepsin S, N-[2-chloro-5-(1-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-6-oxo-1,6-dihydropyridazin-3-yl)benzyl]benzamide | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | 主引用文献 | Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors Bioorg.Med.Chem.Lett., 20, 2010
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5QBY
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![BU of 5qby by Molmil](/molmil-images/mine/5qby) | Crystal structure of human Cathepsin-S with bound ligand | 分子名称: | Cathepsin S, N-[2-chloro-5-(1-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-6-oxo-1,6-dihydropyrimidin-5-yl)benzyl]-4-fluorobenzamide | 著者 | Bembenek, S.D, Ameriks, M.K, Mirzadegan, T, Yang, H, Shao, C, Burley, S.K. | 登録日 | 2017-08-04 | 公開日 | 2017-12-20 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors Bioorg.Med.Chem.Lett., 20, 2010
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