Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 140 件
3V51
DownloadVisualize
BU of 3v51 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor RM-1-176
分子名称: 3-{6-[(3-chlorobenzyl)oxy]naphthalen-2-yl}-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Merritt, E.A, Larson, E.T.
登録日2011-12-15
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1.
J.Med.Chem., 55, 2012
3V5P
DownloadVisualize
BU of 3v5p by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1288
分子名称: 3-(4-methoxy-3-methylphenyl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Merritt, E.A, Larson, E.T.
登録日2011-12-16
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1.
J.Med.Chem., 55, 2012
3UPX
DownloadVisualize
BU of 3upx by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1300
分子名称: Calmodulin-domain protein kinase 1, [2-amino-1-(piperidin-4-ylmethyl)-1H-benzimidazol-6-yl](phenyl)methanone
著者Merritt, E.A, Larson, E.T.
登録日2011-11-18
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1.
J.Med.Chem., 55, 2012
4DS2
DownloadVisualize
BU of 4ds2 by Molmil
Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
分子名称: Ubiquitin-conjugating enzyme E2, putative
著者Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2012-02-17
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
To be Published
1HTL
DownloadVisualize
BU of 1htl by Molmil
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
分子名称: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
著者Merritt, E.A, Hol, W.G.J.
登録日1995-02-15
公開日1995-04-20
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
4MXA
DownloadVisualize
BU of 4mxa by Molmil
CDPK1 from Neospora caninum in complex with inhibitor RM-1-132
分子名称: 3-(6-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-like domain protein kinase isoenzyme gamma, related
著者Merritt, E.A.
登録日2013-09-26
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Neospora caninum Calcium-Dependent Protein Kinase 1 Is an Effective Drug Target for Neosporosis Therapy.
Plos One, 9, 2014
4MX9
DownloadVisualize
BU of 4mx9 by Molmil
CDPK1 from Neospora caninum in complex with inhibitor UW1294
分子名称: 3-(6-ethoxynaphthalen-2-yl)-1-[(1-methylpiperidin-4-yl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-like domain protein kinase isoenzyme gamma, related
著者Merritt, E.A.
登録日2013-09-26
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Neospora caninum Calcium-Dependent Protein Kinase 1 Is an Effective Drug Target for Neosporosis Therapy.
Plos One, 9, 2014
4M97
DownloadVisualize
BU of 4m97 by Molmil
Calcium-Dependent Protein Kinase 1 from Neospora caninum
分子名称: Calmodulin-like domain protein kinase isoenzyme gamma, related
著者Merritt, E.A.
登録日2013-08-14
公開日2013-10-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Neospora caninum Calcium-Dependent Protein Kinase 1 Is an Effective Drug Target for Neosporosis Therapy.
Plos One, 9, 2014
3CHB
DownloadVisualize
BU of 3chb by Molmil
CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHOLERA TOXIN, UNKNOWN ATOM OR ION, ...
著者Merritt, E.A, Hol, W.G.J.
登録日1998-03-24
公開日1998-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.
J.Mol.Biol., 282, 1998
1CT1
DownloadVisualize
BU of 1ct1 by Molmil
CHOLERA TOXIN B-PENTAMER MUTANT G33R BOUND TO RECEPTOR PENTASACCHARIDE
分子名称: CHLORIDE ION, CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Merritt, E.A, Hol, W.G.J.
登録日1997-06-03
公開日1997-10-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of receptor binding by cholera toxin mutants.
Protein Sci., 6, 1997
1QCB
DownloadVisualize
BU of 1qcb by Molmil
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
分子名称: PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
著者Merritt, E.A, Hol, W.G.J.
登録日1999-04-30
公開日2003-06-10
最終更新日2021-07-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb
To be Published
1QB5
DownloadVisualize
BU of 1qb5 by Molmil
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
分子名称: PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
著者Merritt, E.A, Hol, W.G.J.
登録日1999-04-30
公開日2003-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb
To be Published
2CHB
DownloadVisualize
BU of 2chb by Molmil
CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
分子名称: CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Merritt, E.A, Hol, W.G.J.
登録日1997-06-03
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural studies of receptor binding by cholera toxin mutants.
Protein Sci., 6, 1997
1VJQ
DownloadVisualize
BU of 1vjq by Molmil
Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability.
分子名称: designed protein
著者Merritt, E.A, Baker, D, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-03-19
公開日2004-03-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability.
To be Published
3S4O
DownloadVisualize
BU of 3s4o by Molmil
Protein Tyrosine Phosphatase (putative) from Leishmania major
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase-like protein, THIOSULFATE
著者Merritt, E.A, Arakaki, T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP), Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2011-05-19
公開日2011-06-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Protein Tyrosine Phosphatase from Leishmania major
To be Published
2Q0X
DownloadVisualize
BU of 2q0x by Molmil
Alpha/Beta hydrolase fold protein of unknown function
分子名称: GLYCEROL, Uncharacterized protein
著者Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2007-05-22
公開日2007-06-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function.
Acta Crystallogr.,Sect.F, 64, 2008
1FER
DownloadVisualize
BU of 1fer by Molmil
STRUCTURE AT PH 6.5 OF FERREDOXIN I FROM AZOTOBACTER VINELANDII AT 2.3 ANGSTROMS RESOLUTION
分子名称: FE3-S4 CLUSTER, FERREDOXIN I, IRON/SULFUR CLUSTER
著者Merritt, E.A, Stout, G.H, Turley, S, Sieker, L.C, Jensen, L.H, Orme-Johnson, W.H.
登録日1992-09-02
公開日1993-04-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure at pH 6.5 of ferredoxin I from Azotobacter vinelandii at 2.3 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
4YSM
DownloadVisualize
BU of 4ysm by Molmil
Calcium-Dependent Protein Kinase from Eimeria tenella
分子名称: CALCIUM ION, Calmodulin-like domain protein kinase
著者Merritt, E.A.
登録日2015-03-17
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献CDPK is a druggable target in the apicomplexan parasite Eimeria
to be published
4YUQ
DownloadVisualize
BU of 4yuq by Molmil
CDPK1 from Eimeria tenella in complex with inhibitor UW1354
分子名称: 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, Calmodulin-like domain protein kinase
著者Merritt, E.A.
登録日2015-03-19
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CDPK is a druggable target in the apicomplexan parasite Eimeria
to be published
4YZB
DownloadVisualize
BU of 4yzb by Molmil
CDPK1 from Eimeria tenella in complex with inhibitor UW1521
分子名称: 4-(6-ethoxynaphthalen-2-yl)-6-(piperazin-1-ylmethyl)-2H-indazol-3-amine, CALCIUM ION, Calmodulin-like domain protein kinase
著者Merritt, E.A.
登録日2015-03-24
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献CDPK is a druggable target in the apicomplexan parasite Eimeria
to be published
2QOR
DownloadVisualize
BU of 2qor by Molmil
Crystal structure of Plasmodium vivax guanylate kinase
分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, PYROPHOSPHATE 2-
著者Merritt, E.A, Le Trong, I, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2007-07-20
公開日2007-08-07
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Plasmodium vivax guanylate kinase.
To be Published
3SO4
DownloadVisualize
BU of 3so4 by Molmil
Methionine-adenosyltransferase from Entamoeba histolytica
分子名称: ACETATE ION, Methionine-adenosyltransferase
著者Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2011-06-29
公開日2011-07-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Methionine-adenosyltransferase from Entamoeba histolytica
To be Published
3P0I
DownloadVisualize
BU of 3p0i by Molmil
Leishmania major Tyrosyl-tRNA synthetase in complex with tyrosinol, cubic crystal form
分子名称: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, Tyrosyl-tRNA synthetase
著者Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2010-09-28
公開日2011-03-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer.
J.Mol.Biol., 409, 2011
1LT5
DownloadVisualize
BU of 1lt5 by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH THIODIGALACTOSIDE
分子名称: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose
著者Merritt, E.A, Hol, W.G.J.
登録日1997-09-30
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
Structure, 5, 1997
1LT6
DownloadVisualize
BU of 1lt6 by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH METANITROPHENYLGALACTOSIDE
分子名称: 3-nitrophenyl alpha-D-galactopyranoside, HEAT-LABILE ENTEROTOXIN
著者Merritt, E.A, Hol, W.G.J.
登録日1997-10-01
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
Structure, 5, 1997

223790

件を2024-08-14に公開中

PDB statisticsPDBj update infoContact PDBjnumon