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PDB: 2 件

1VSN
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BU of 1vsn by Molmil
Crystal structure of a potent small molecule inhibitor bound to cathepsin K
分子名称: Cathepsin K, N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE
著者McGrath, M.
登録日2007-03-19
公開日2007-04-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of a potent and selective non-basic cathepsin K inhibitor.
Bioorg.Med.Chem.Lett., 16, 2006
6DGT
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BU of 6dgt by Molmil
Selective PI3K beta inhibitor bound to PI3K delta
分子名称: 4-[1-(5,8-difluoroquinolin-4-yl)-2-methyl-4-(4H-1,2,4-triazol-3-yl)-1H-benzimidazol-6-yl]-3-fluoropyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
著者Somoza, J, Villasenor, A, McGrath, M.
登録日2018-05-18
公開日2018-08-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) beta Inhibitor.
J. Med. Chem., 61, 2018

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件を2024-07-24に公開中

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