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PDB: 35 件
1ASK
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NUCLEAR TRANSPORT FACTOR 2 (NTF2) H66A MUTANT
分子名称: NUCLEAR TRANSPORT FACTOR 2
著者Mccoy, A.J, Stewart, M.J.
登録日1997-08-11
公開日1998-01-28
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1AR0
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NUCLEAR TRANSPORT FACTOR 2 (NTF2) E42K MUTANT
分子名称: NUCLEAR TRANSPORT FACTOR 2
著者Mccoy, A.J, Stewart, M.J.
登録日1997-08-08
公開日1997-12-24
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1QFH
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DIMERIZATION OF GELATION FACTOR FROM DICTYOSTELIUM DISCOIDEUM: CRYSTAL STRUCTURE OF ROD DOMAINS 5 AND 6
分子名称: PROTEIN (GELATION FACTOR)
著者Mccoy, A.J, Fucini, P, Noegel, A.A, Stewart, M.
登録日1999-04-11
公開日1999-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod.
Nat.Struct.Biol., 6, 1999
5JP2
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Fcho1 Mu homology domain (Danio Rerio) with bound Eps15 peptide
分子名称: Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
著者McCoy, A.J, Wrobel, A, Owen, D.J.
登録日2016-05-03
公開日2016-06-08
最終更新日2016-06-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
1E03
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PLASMA ALPHA ANTITHROMBIN-III AND PENTASACCHARIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ...
著者McCoy, A.J, Jin, L, Abrahams, J.-P, Skinner, R, Carrell, R.W.
登録日2000-03-09
公開日2000-06-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1DZH
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P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
著者Mccoy, A.J, Huntington, J.A, Carrell, R.W.
登録日2000-02-28
公開日2000-05-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
1E05
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PLASMA ALPHA ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
著者McCoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W.
登録日2000-03-09
公開日2000-06-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1DZG
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N135Q-S380C-ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ...
著者McCoy, A.J, Huntington, J.A, Carrell, R.W.
登録日2000-02-28
公開日2000-05-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.
J.Biol.Chem., 275, 2000
1E04
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PLASMA BETA ANTITHROMBIN-III
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, GLYCEROL, ...
著者Mccoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W.
登録日2000-03-09
公開日2000-06-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity.
J.Mol.Biol., 326, 2003
1WBA
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WINGED BEAN ALBUMIN 1
分子名称: WINGED BEAN ALBUMIN 1
著者Mccoy, A.J.
登録日1996-06-19
公開日1997-01-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystallization and preliminary crystallographic data of the major albumin from Psophocarpus tetragonolobus (L.) DC.
J.Biol.Chem., 262, 1987
6Z32
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Human cation-independent mannose 6-phosphate/IGF2 receptor domains 7-11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor, SULFATE ION, ...
著者Bochel, A.J, Williams, C, McCoy, A.J, Hoppe, H, Winter, A.J, Nicholls, R.D, Harlos, K, Jones, Y.E, Berger, I, Hassan, B, Crump, M.P.
登録日2020-05-19
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Structure, 28, 2020
1A14
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COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 5 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NC10 FV (HEAVY CHAIN), ...
著者Malby, R.L, Mccoy, A.J, Kortt, A.A, Hudson, P.J, Colman, P.M.
登録日1997-12-21
公開日1998-05-13
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-dimensional structures of single-chain Fv-neuraminidase complexes.
J.Mol.Biol., 279, 1998
1BYU
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CANINE GDP-RAN
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING PROTEIN RAN)
著者Stewart, M, Kent, H.M, Mccoy, A.J.
登録日1998-10-18
公開日1998-12-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
1NMC
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COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEURAMINIDASE, ...
著者Malby, R.L, Mccoy, A.J, Kortt, A.A, Hudson, P.J, Colman, P.M.
登録日1997-12-21
公開日1998-09-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-dimensional structures of single-chain Fv-neuraminidase complexes.
J.Mol.Biol., 279, 1998
2XA7
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AP2 clathrin adaptor core in active complex with cargo peptides
分子名称: ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ...
著者Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J.
登録日2010-03-29
公開日2010-07-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
1QG4
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CANINE GDP-RAN F72Y MUTANT
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
著者Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
登録日1999-04-20
公開日1999-06-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1QG2
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CANINE GDP-RAN R76E MUTANT
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
著者Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
登録日1999-04-20
公開日1999-06-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
4N3E
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Crystal structure of Hyp-1, a St John's wort PR-10 protein, in complex with 8-anilino-1-naphthalene sulfonate (ANS)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-ANILINO-1-NAPHTHALENE SULFONATE, Phenolic oxidative coupling protein, ...
著者Sliwiak, J, Dauter, Z, Mccoy, A.J, Read, R.J, Jaskolski, M.
登録日2013-10-07
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Likelihood-based molecular-replacement solution for a highly pathological crystal with tetartohedral twinning and sevenfold translational noncrystallographic symmetry.
Acta Crystallogr.,Sect.D, 70, 2014
6QH6
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AP2 clathrin adaptor core with two cargo peptides in open+ conformation
分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
登録日2019-01-15
公開日2019-09-04
最終更新日2022-12-07
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH7
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AP2 clathrin adaptor mu2T156-phosphorylated core with two cargo peptides in open+ conformation
分子名称: ADAPTOR-RELATED PROTEIN COMPLEX 2, MU 2 SUBUNIT, C-TERMINAL DOMAIN, ...
著者Wrobel, A.G, Owen, D.J, McCoy, A.J, Evans, P.R.
登録日2019-01-15
公開日2019-09-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
2JKT
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AP2 CLATHRIN ADAPTOR CORE with CD4 Dileucine peptide RM(phosphoS) EIKRLLSE Q to E mutant
分子名称: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
著者Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
登録日2008-08-29
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2JKR
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AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE
分子名称: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
著者Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
登録日2008-08-29
公開日2008-10-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2MSP
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MAJOR SPERM PROTEIN, BETA ISOFORM, ENGINEERED C59S/T90C MUTANT, PUTATIVE SUBFILAMENT STRUCTURE, PH 8.5
分子名称: MAJOR SPERM PROTEIN
著者Bullock, T.L, Mccoy, A.J, Stewart, M.
登録日1997-12-19
公開日1998-04-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for amoeboid motility in nematode sperm.
Nat.Struct.Biol., 5, 1998
2QY7
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Crystal structure of human epsinR ENTH domain
分子名称: Clathrin interactor 1
著者Miller, S.E, Collins, B.M, McCoy, A.J, Robinson, M.S, Owen, D.J.
登録日2007-08-13
公開日2007-11-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles.
Nature, 450, 2007
2VGL
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AP2 CLATHRIN ADAPTOR CORE
分子名称: ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ...
著者Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R.
登録日2007-11-14
公開日2007-12-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002

 

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