3ORC
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1THL
| Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan | 分子名称: | CALCIUM ION, N-({1-[(2S)-2-carboxy-4-phenylbutyl]cyclopentyl}carbonyl)-L-tryptophan, THERMOLYSIN, ... | 著者 | Holland, D.R, Matthews, B.W. | 登録日 | 1993-11-17 | 公開日 | 1994-01-31 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33, 1994
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4BCL
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3MAT
| E.COLI METHIONINE AMINOPEPTIDASE TRANSITION-STATE INHIBITOR COMPLEX | 分子名称: | COBALT (II) ION, METHIONINE AMINOPEPTIDASE, SODIUM ION, ... | 著者 | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | 登録日 | 1999-03-29 | 公開日 | 1999-06-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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2TMN
| CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN | 分子名称: | CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ... | 著者 | Tronrud, D.E, Monzingo, A.F, Matthews, B.W. | 登録日 | 1987-06-29 | 公開日 | 1989-01-09 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986
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4MAT
| E.COLI METHIONINE AMINOPEPTIDASE HIS79ALA MUTANT | 分子名称: | PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION | 著者 | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | 登録日 | 1999-03-29 | 公開日 | 1999-06-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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200L
| THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | 著者 | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | 登録日 | 1995-11-06 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
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258L
| AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME | 分子名称: | CHLORIDE ION, LYSOZYME, ZINC ION | 著者 | Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W. | 登録日 | 1999-01-05 | 公開日 | 2000-09-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site. Protein Eng., 13, 2000
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260L
| AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME | 分子名称: | CHLORIDE ION, NICKEL (II) ION, PROTEIN (LYSOZYME) | 著者 | Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W. | 登録日 | 1999-03-01 | 公開日 | 2000-09-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site. Protein Eng., 13, 2000
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259L
| AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME | 分子名称: | CHLORIDE ION, COBALT (II) ION, PROTEIN (LYSOZYME) | 著者 | Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W. | 登録日 | 1999-02-10 | 公開日 | 1999-04-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site. Protein Eng., 13, 2000
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257L
| AN ADAPTABLE METAL-BINDING SITE ENGINEERED INTO T4 LYSOZYME | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME) | 著者 | Wray, J.W, Baase, W.A, Ostheimer, G.J, Matthews, B.W. | 登録日 | 1999-01-05 | 公開日 | 2000-09-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site. Protein Eng., 13, 2000
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1P5C
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1P56
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221L
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224L
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1QUG
| E108V MUTANT OF T4 LYSOZYME | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME) | 著者 | Wray, J, Baase, W.A, Lindstrom, J.D, Poteete, A.R, Matthews, B.W. | 登録日 | 1999-07-01 | 公開日 | 1999-07-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability. J.Mol.Biol., 292, 1999
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1QSQ
| CAVITY CREATING MUTATION | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME | 著者 | Gassner, N.C, Baase, W.A, Lindstrom, J, Matthews, B.W. | 登録日 | 1999-06-22 | 公開日 | 1999-06-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding. Biochemistry, 38, 1999
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1QT5
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2LZM
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1QT4
| T26Q MUTANT OF T4 LYSOZYME | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (T4 LYSOZYME) | 著者 | Kuroki, R, Weaver, L.H, Matthews, B.W. | 登録日 | 1999-06-30 | 公開日 | 1999-07-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site. Proc.Natl.Acad.Sci.USA, 96, 1999
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1QT6
| E11H Mutant of T4 Lysozyme | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (T4 LYSOZYME) | 著者 | Kuroki, R, Weaver, L.H, Matthews, B.W. | 登録日 | 1999-06-30 | 公開日 | 1999-07-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site. Proc.Natl.Acad.Sci.USA, 96, 1999
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1T8A
| USE OF SEQUENCE DUPLICATION TO ENGINEER A LIGAND-TRIGGERED LONG-DISTANCE MOLECULAR SWITCH IN T4 Lysozyme | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, GUANIDINE, ... | 著者 | Yousef, M.S, Baase, W.A, Matthews, B.W. | 登録日 | 2004-05-11 | 公開日 | 2004-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme. Proc.Natl.Acad.Sci.USA, 101, 2004
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1T97
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1MAT
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1CVK
| T4 LYSOZYME MUTANT L118A | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME | 著者 | Gassner, N.C, Baase, W.A, Lindstrom, J, Lu, J, Matthews, B.W. | 登録日 | 1999-08-23 | 公開日 | 1999-11-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding. Biochemistry, 38, 1999
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