1UJ2
| Crystal structure of human uridine-cytidine kinase 2 complexed with products, CMP and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Suzuki, N.N, Koizumi, K, Fukushima, M, Matsuda, A, Inagaki, F. | Deposit date: | 2003-07-25 | Release date: | 2004-05-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase STRUCTURE, 12, 2004
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1UEI
| Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, UTP | Descriptor: | URIDINE 5'-TRIPHOSPHATE, Uridine-cytidine kinase 2 | Authors: | Suzuki, N.N, Koizumi, K, Fukushima, M, Matsuda, A, Inagaki, F. | Deposit date: | 2003-05-16 | Release date: | 2004-05-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase STRUCTURE, 12, 2004
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1UDW
| Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, CTP | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, Uridine-cytidine kinase 2 | Authors: | Suzuki, N.N, Koizumi, K, Fukushima, M, Matsuda, A, Inagaki, F. | Deposit date: | 2003-05-07 | Release date: | 2004-05-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase STRUCTURE, 12, 2004
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1UFQ
| Crystal structure of ligand-free human uridine-cytidine kinase 2 | Descriptor: | Uridine-cytidine kinase 2 | Authors: | Suzuki, N.N, Koizumi, K, Fukushima, M, Matsuda, A, Inagaki, F. | Deposit date: | 2003-06-06 | Release date: | 2004-05-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase STRUCTURE, 12, 2004
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7DCZ
| Crystal Structure of BACE1 in complex with N-{3-[(4S)-2-amino-4-methyl-4H-1,3-thiazin-4-yl]-4- fluorophenyl}-5-cyanopyridine-2-carboxamide | Descriptor: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | Authors: | Koriyama, Y, Hori, A, Ito, H, Yonezawa, S, Baba, Y, Tanimoto, N, Ueno, T, Yamamoto, S, Yamamoto, T, Asada, N, Morimoto, K, Einaru, S, Sakai, K, Kanazu, T, Matsuda, A, Yamaguchi, Y, Oguma, T, Timmers, M, Tritsmans, L, Kusakabe, K.I, Kato, A, Sakaguchi, G. | Deposit date: | 2020-10-27 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based beta-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial. J.Med.Chem., 64, 2021
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