1A7E
 
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1A7D
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8P4G
 | | Crystal structure of a multicopper oxidase 3F3 variant from Pyrobaculum aerophilum | | 分子名称: | CHLORIDE ION, COPPER (II) ION, Multicopper oxidase | | 著者 | Borges, P.T, Brissos, V, Frazao, C, Martins, L.O. | | 登録日 | 2023-05-21 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Flexible active-site loops fine-tune substrate specificity of hyperthermophilic metallo-oxidases.
J.Biol.Inorg.Chem., 29, 2024
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7PL0
 | | Crystal structure of a DyP-type peroxidase 5G5 variant from Bacillus subtilis | | 分子名称: | Deferrochelatase/peroxidase, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Borges, P.T, Rodrigues, C, Silva, D, Taborda, A, Brissos, V, Frazao, C, Martins, L.O. | | 登録日 | 2021-08-27 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Loops around the Heme Pocket Have a Critical Role in the Function and Stability of Bs DyP from Bacillus subtilis .
Int J Mol Sci, 22, 2021
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7PKX
 | | Crystal structure of a DyP-type peroxidase from Bacillus subtilis in P3121 space group | | 分子名称: | Deferrochelatase/peroxidase, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Borges, P.T, Rodrigues, C, Silva, D, Taborda, A, Brissos, V, Frazao, C, Martins, L.O. | | 登録日 | 2021-08-27 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.491 Å) | | 主引用文献 | Loops around the Heme Pocket Have a Critical Role in the Function and Stability of Bs DyP from Bacillus subtilis .
Int J Mol Sci, 22, 2021
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7QYQ
 | | Crystal structure of a DyP-type peroxidase from Pseudomonas putida | | 分子名称: | Dyp-type peroxidase family protein, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Borges, P.T, Silva, D, Frazao, C, Martins, L.O. | | 登録日 | 2022-01-28 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | | 主引用文献 | Unveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase.
Comput Struct Biotechnol J, 20, 2022
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7QZA
 | | Crystal structure of a DyP-type peroxidase 29E4 variant from Pseudomonas putida | | 分子名称: | Dyp-type peroxidase family protein, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Borges, P.T, Silva, D, Frazao, C, Martins, L.O. | | 登録日 | 2022-01-30 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | Unveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase.
Comput Struct Biotechnol J, 20, 2022
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7QFD
 | | Crystal structure of a bacterial pyranose 2-oxidase complex with D-glucose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, GMC oxidoreductase family protein, ... | | 著者 | Borges, P.T, Frazao, T, Taborda, A, Frazao, C, Martins, L.O. | | 登録日 | 2021-12-05 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Mechanistic insights into glycoside 3-oxidases involved in C-glycoside metabolism in soil microorganisms.
Nat Commun, 14, 2023
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7QF8
 | | Crystal structure of a bacterial pyranose 2-oxidase from Pseudoarthrobacter siccitolerans | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, GMC oxidoreductase family protein, ... | | 著者 | Borges, P.T, Frazao, T, Taborda, A, Frazao, C, Martins, L.O. | | 登録日 | 2021-12-04 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.009 Å) | | 主引用文献 | Mechanistic insights into glycoside 3-oxidases involved in C-glycoside metabolism in soil microorganisms.
Nat Commun, 14, 2023
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7QVA
 | | Crystal structure of a bacterial pyranose 2-oxidase in complex with mangiferin | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GMC oxidoreductase family protein, Mangiferin, ... | | 著者 | Borges, P.T, Frazao, T, Taborda, T, Brissos, V, Frazao, C, Martins, L.O. | | 登録日 | 2022-01-20 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Mechanistic insights into glycoside 3-oxidases involved in C-glycoside metabolism in soil microorganisms.
Nat Commun, 14, 2023
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7QYZ
 | | Crystal structure of a DyP-type peroxidase 6E10 variant from Pseudomonas putida | | 分子名称: | Dyp-type peroxidase family protein, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Borges, P.T, Silva, D, Martins, L.O, Frazao, C. | | 登録日 | 2022-01-30 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.452 Å) | | 主引用文献 | Unveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase.
Comput Struct Biotechnol J, 20, 2022
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1OF0
 | | CRYSTAL STRUCTURE OF BACILLUS SUBTILIS COTA AFTER 1H SOAKING WITH ABTS | | 分子名称: | 3-ETHYL-2-[(2Z)-2-(3-ETHYL-6-SULFO-1,3-BENZOTHIAZOL-2(3H)-YLIDENE)HYDRAZINO]-6-SULFO-3H-1,3-BENZOTHIAZOL-1-IUM, COPPER (I) ION, CU-O LINKAGE, ... | | 著者 | Enguita, F.J, Marcal, D, Grenha, R, Martins, L.O, Henriques, A.O, Carrondo, M.A. | | 登録日 | 2003-04-03 | | 公開日 | 2004-05-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural Characterization of a Bacterial Laccase Reaction Cycle
To be Published
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1W6L
 | | 3D structure of CotA incubated with CuCl2 | | 分子名称: | COPPER (II) ION, GLYCEROL, OXYGEN MOLECULE, ... | | 著者 | Bento, I, Martins, L.O, Lopes, G.G, Carrondo, M.A, Lindley, P.F. | | 登録日 | 2004-08-19 | | 公開日 | 2005-10-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Dioxygen Reduction by Multi-Copper Oxidases; a Structural Perspective.
Dalton Trans., 7, 2005
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1W6W
 | | 3D structure of CotA incubated with sodium azide | | 分子名称: | AZIDE ION, COPPER (II) ION, GLYCEROL, ... | | 著者 | Bento, I, Martins, L.O, Lopes, G.G, Carrondo, M.A, Lindley, P.F. | | 登録日 | 2004-08-24 | | 公開日 | 2005-10-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Dioxygen Reduction by Multi-Copper Oxidases; a Structural Perspective.
Dalton Trans., 7, 2005
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1W8E
 | | 3D structure of CotA incubated with hydrogen peroxide | | 分子名称: | COPPER (II) ION, GLYCEROL, PEROXIDE ION, ... | | 著者 | Bento, I, Martins, L.O, Lopes, G.G, Carrondo, M.A, Lindley, P.F. | | 登録日 | 2004-09-21 | | 公開日 | 2005-10-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Dioxygen Reduction by Multi-Copper Oxidases; a Structural Perspective.
Dalton Trans., 7, 2005
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1GSK
 | | Crystal structure of CotA, an endospore coat protein from Bacillus subtilis | | 分子名称: | COPPER (II) ION, CU-O LINKAGE, CU-O-CU LINKAGE, ... | | 著者 | Enguita, F.J, Matias, P.M, Martins, L.O, Henriques, A.O, Carrondo, M.A. | | 登録日 | 2002-01-08 | | 公開日 | 2003-05-21 | | 最終更新日 | 2011-10-26 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of a Bacterial Endospore Coat Component: A Laccase with Enhanced Thermostability Properties
J.Biol.Chem., 278, 2003
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6TTD
 | | Crystal structure of McoA multicopper oxidase 2F4 variant from the hyperthermophile Aquifex aeolicus | | 分子名称: | COPPER (II) ION, GLYCEROL, Multicopper oxidase, ... | | 著者 | Borges, P.T, Brissos, V, Cordeiro, T.N, Martins, L.O, Frazao, C. | | 登録日 | 2019-12-26 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Distal Mutations Shape Substrate-Binding Sites during Evolution of a Metallo-Oxidase into a Laccase
Acs Catalysis, 2022
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2BHF
 | | 3D structure of the reduced form of CotA | | 分子名称: | COPPER (I) ION, GLYCEROL, SPORE COAT PROTEIN A | | 著者 | Bento, I, Martins, L.O, Lopes, G.G, Carrondo, M.A, Lindley, P.F. | | 登録日 | 2005-01-10 | | 公開日 | 2005-10-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Dioxygen Reduction by Multi-Copper Oxidases; a Structural Perspective.
Dalton Trans., 7, 2005
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2V35
 | | Porcine Pancreatic Elastase in complex with inhibitor JM54 | | 分子名称: | (2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACID, ELASTASE-1, GLYCEROL, ... | | 著者 | Oliveira, T.F, Mulchande, J, Martins, L, Moreira, R, Iley, J, Archer, M. | | 登録日 | 2007-06-12 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | The Efficiency of C-4 Substituents in Activating the Beta-Lactam Scaffold Towards Serine Proteases and Hydroxide Ion.
Org.Biomol.Chem., 5, 2007
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4AKQ
 | | Mutations in the neighbourhood of CotA-laccase trinuclear site: E498D mutant | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, OXYGEN MOLECULE, ... | | 著者 | Silva, C.S, Chen, Z, Durao, P, Pereira, M.M, Todorovic, S, Hildebrandt, P, Martins, L.O, Lindley, P.F, Bento, I. | | 登録日 | 2012-02-28 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Role of Glu498 in the Dioxygen Reactivity of Cota-Laccase from Bacillus Subtilis.
Dalton Trans, 39, 2010
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4AKO
 | | Mutations in the neighbourhood of CotA-laccase trinuclear site: E498L mutant | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, OXYGEN MOLECULE, ... | | 著者 | Silva, C.S, Chen, Z, Durao, P, Pereira, M.M, Todorovic, S, Hildebrandt, P, Martins, L.O, Lindley, P.F, Bento, I. | | 登録日 | 2012-02-28 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Role of Glu498 in the Dioxygen Reactivity of Cota-Laccase from Bacillus Subtilis.
Dalton Trans, 39, 2010
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4AKP
 | | Mutations in the neighbourhood of CotA-laccase trinuclear site: E498T mutant | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, OXYGEN MOLECULE, ... | | 著者 | Silva, C.S, Chen, Z, Durao, P, Pereira, M.M, Todorovic, S, Hildebrandt, P, Martins, L.O, Lindley, P.F, Bento, I. | | 登録日 | 2012-02-28 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Role of Glu498 in the Dioxygen Reactivity of Cota-Laccase from Bacillus Subtilis.
Dalton Trans, 39, 2010
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6SYY
 | | Crystal structure of McoA multicopper oxidase from the hyperthermophile Aquifex aeolicus | | 分子名称: | COPPER (II) ION, OXYGEN ATOM, Periplasmic cell division protein (SufI) | | 著者 | Borges, P.T, Brissos, V, Cordeiro, T.N, Martins, L.O, Frazao, C. | | 登録日 | 2019-10-01 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.794 Å) | | 主引用文献 | The Methionine-Rich Loop of Multicopper Oxidase McoA follows Open-To-Close Transitions with a Role in Enzyme Catalysis
Acs Catalysis, 2020
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2X87
 | | Crystal Structure of the reconstituted CotA | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, HYDROXIDE ION, ... | | 著者 | Bento, I, Silva, C.S, Chen, Z, Martins, L.O, Lindley, P.F, Soares, C.M. | | 登録日 | 2010-03-06 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanisms Underlying Dioxygen Reduction in Laccases. Structural and Modelling Studies Focusing on Proton Transfer.
Bmc Struct.Biol., 10, 2010
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2WSD
 | | Proximal mutations at the type 1 Cu site of CotA-laccase: I494A mutant | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, OXYGEN MOLECULE, ... | | 著者 | Silva, C.S, Durao, P, Chen, Z, Soares, C.M, Pereira, M.M, Todorovic, S, Hildebrandt, P, Martins, L.O, Lindley, P.F, Bento, I. | | 登録日 | 2009-09-04 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Proximal Mutations at the Type 1 Copper Site of Cota Laccase: Spectroscopic, Redox, Kinetic and Structural Characterization of I494A and L386A Mutants.
Biochem.J., 412, 2008
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