7FDS
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![BU of 7fds by Molmil](/molmil-images/mine/7fds) | High resolution crystal structure of LpqH from Mycobacterium tuberculosis | Descriptor: | Lipoprotein LpqH | Authors: | Kundapura, S.V, Chatterjee, S, Samanta, D, Ramagopal, U.A. | Deposit date: | 2021-07-17 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.258 Å) | Cite: | High-resolution crystal structure of LpqH, an immunomodulatory surface lipoprotein of Mycobacterium tuberculosis reveals a distinct fold and a conserved cleft on its surface. Int.J.Biol.Macromol., 210, 2022
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2YKN
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![BU of 2ykn by Molmil](/molmil-images/mine/2ykn) | Crystal structure of HIV-1 Reverse Transcriptase (RT) in complex with a Difluoromethylbenzoxazole (DFMB) Pyrimidine Thioether derivative, a non-nucleoside RT inhibitor (NNRTI) | Descriptor: | 2-[DIFLUORO-[(4-METHYL-PYRIMIDINYL)-THIO]METHYL]-BENZOXAZOLE, CALCIUM ION, REVERSE TRANSCRIPTASE/RIBONUCLEASE H | Authors: | Boyer, J, Arnoult, E, Medebielle, M, Guillemont, J, Unge, T, Unge, J, Jochmans, D. | Deposit date: | 2011-05-28 | Release date: | 2011-08-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Difluoromethylbenzoxazole Pyrimidine Thioether Derivatives: A Novel Class of Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. J.Med.Chem., 54, 2011
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1Z93
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![BU of 1z93 by Molmil](/molmil-images/mine/1z93) | Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer. | Descriptor: | Carbonic anhydrase III, ZINC ION | Authors: | Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. | Deposit date: | 2005-03-31 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
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1ZLJ
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![BU of 1zlj by Molmil](/molmil-images/mine/1zlj) | Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR C-terminal Domain | Descriptor: | Dormancy Survival Regulator | Authors: | Wisedchaisri, G, Wu, M, Rice, A.E, Roberts, D.M, Sherman, D.R, Hol, W.G.J. | Deposit date: | 2005-05-06 | Release date: | 2006-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Mycobacterium tuberculosis DosR and DosR-DNA complex involved in gene activation during adaptation to hypoxic latency. J.Mol.Biol., 354, 2005
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2O0I
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![BU of 2o0i by Molmil](/molmil-images/mine/2o0i) | crystal structure of the R185A mutant of the N-terminal domain of the Group B Streptococcus Alpha C protein | Descriptor: | C protein alpha-antigen | Authors: | Hogle, J.M, Filman, D.J, Baron, M.J, Madoff, L.C, Iglesias, A. | Deposit date: | 2006-11-27 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B streptococci into host cells. J.Biol.Chem., 282, 2007
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2CNW
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![BU of 2cnw by Molmil](/molmil-images/mine/2cnw) | GDPALF4 complex of the SRP GTPases Ffh and FtsY | Descriptor: | CELL DIVISION PROTEIN FTSY, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ... | Authors: | Focia, P.J, Gawronski-Salerno, J, Coon V, J.S, Freymann, D.M. | Deposit date: | 2006-05-24 | Release date: | 2006-10-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structure of a Gdp:Alf(4) Complex of the Srp Gtpases Ffh and Ftsy, and Identification of a Peripheral Nucleotide Interaction Site. J.Mol.Biol., 360, 2006
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6TSQ
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![BU of 6tsq by Molmil](/molmil-images/mine/6tsq) | Marasmius oreades agglutinin (MOA) activated by manganese (II) | Descriptor: | 1,2-ETHANEDIOL, Agglutinin, CALCIUM ION, ... | Authors: | Cordara, G, Manna, D, Krengel, U. | Deposit date: | 2019-12-21 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti . Curr Res Struct Biol, 2, 2020
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1PIV
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![BU of 1piv by Molmil](/molmil-images/mine/1piv) | BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14 | Descriptor: | 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, MYRISTIC ACID, POLIOVIRUS TYPE 3 (SUBUNIT VP1), ... | Authors: | Hiremath, C.N, Grant, R.A, Filman, D.J, Hogle, J.M. | Deposit date: | 1995-02-02 | Release date: | 1995-06-03 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14. Acta Crystallogr.,Sect.D, 51, 1995
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1PVC
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![BU of 1pvc by Molmil](/molmil-images/mine/1pvc) | |
6TSL
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![BU of 6tsl by Molmil](/molmil-images/mine/6tsl) | Marasmius oreades agglutinin (MOA) in complex with the truncated PVPRAHS synthetic substrate | Descriptor: | 1,2-ETHANEDIOL, Agglutinin, CALCIUM ION, ... | Authors: | Cordara, G, Manna, D, Krengel, U. | Deposit date: | 2019-12-20 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti . Curr Res Struct Biol, 2, 2020
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1AS3
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![BU of 1as3 by Molmil](/molmil-images/mine/1as3) | GDP BOUND G42V GIA1 | Descriptor: | GIA1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION | Authors: | Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R. | Deposit date: | 1997-08-11 | Release date: | 1997-11-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1. Biochemistry, 36, 1997
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1YTR
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![BU of 1ytr by Molmil](/molmil-images/mine/1ytr) | NMR structure of plantaricin a in dpc micelles, 20 structures | Descriptor: | Bacteriocin plantaricin A | Authors: | Kristiansen, P.E, Fimland, G, Mantzilas, D, Nissen-Meyer, J. | Deposit date: | 2005-02-11 | Release date: | 2005-05-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure and mode of action of the membrane-permeabilizing antimicrobial peptide pheromone plantaricin A J.Biol.Chem., 280, 2005
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1AS0
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![BU of 1as0 by Molmil](/molmil-images/mine/1as0) | GTP-GAMMA-S BOUND G42V GIA1 | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GIA1, MAGNESIUM ION, ... | Authors: | Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R. | Deposit date: | 1997-08-11 | Release date: | 1997-11-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1. Biochemistry, 36, 1997
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6TSM
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![BU of 6tsm by Molmil](/molmil-images/mine/6tsm) | Marasmius oreades agglutinin (MOA) in complex with the truncated PVVRAHS synthetic substrate | Descriptor: | 1,2-ETHANEDIOL, Agglutinin, CALCIUM ION, ... | Authors: | Cordara, G, Manna, D, Krengel, U. | Deposit date: | 2019-12-20 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti . Curr Res Struct Biol, 2, 2020
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1AS2
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![BU of 1as2 by Molmil](/molmil-images/mine/1as2) | GDP+PI BOUND G42V GIA1 | Descriptor: | GIA1, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION | Authors: | Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R. | Deposit date: | 1997-08-11 | Release date: | 1997-11-12 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1. Biochemistry, 36, 1997
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5LRX
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![BU of 5lrx by Molmil](/molmil-images/mine/5lrx) | Structure of A20 OTU domain bound to ubiquitin | Descriptor: | Polyubiquitin-B, Tumor necrosis factor alpha-induced protein 3 | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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6TSR
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![BU of 6tsr by Molmil](/molmil-images/mine/6tsr) | Marasmius oreades agglutinin (MOA) activated by manganese (II) and calcium | Descriptor: | 1,2-ETHANEDIOL, Agglutinin, CALCIUM ION, ... | Authors: | Cordara, G, Manna, D, Krengel, U. | Deposit date: | 2019-12-21 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti . Curr Res Struct Biol, 2, 2020
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6TSO
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![BU of 6tso by Molmil](/molmil-images/mine/6tso) | Marasmius oreades agglutinin (MOA) inhibited by cadmium | Descriptor: | 1,2-ETHANEDIOL, Agglutinin, CADMIUM ION, ... | Authors: | Cordara, G, Manna, D, Krengel, U. | Deposit date: | 2019-12-20 | Release date: | 2020-07-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti . Curr Res Struct Biol, 2, 2020
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8DI5
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![BU of 8di5 by Molmil](/molmil-images/mine/8di5) | Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with VH domain F6 (focused refinement of RBD and VH F6) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VH F6 | Authors: | Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Subramaniam, S. | Deposit date: | 2022-06-28 | Release date: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains. Iscience, 25, 2022
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2ADP
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![BU of 2adp by Molmil](/molmil-images/mine/2adp) | Nitrated Human Manganese Superoxide Dismutase | Descriptor: | MANGANESE (II) ION, POTASSIUM ION, Superoxide dismutase [Mn] | Authors: | Quint, P, Reutzel, R, Mikulski, R, McKenna, R, Silverman, D.N. | Deposit date: | 2005-07-20 | Release date: | 2006-07-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of nitrated human manganese superoxide dismutase: mechanism of inactivation. FREE RADIC.BIOL.MED., 40, 2006
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1M3A
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![BU of 1m3a by Molmil](/molmil-images/mine/1m3a) | Solution structure of a circular form of the truncated N-terminal SH3 domain from oncogene protein c-Crk. | Descriptor: | Proto-oncogene C-crk | Authors: | Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D. | Deposit date: | 2002-06-27 | Release date: | 2003-08-05 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain To be Published
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2ADQ
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![BU of 2adq by Molmil](/molmil-images/mine/2adq) | Human Manganese Superoxide Dismutase | Descriptor: | MANGANESE (II) ION, POTASSIUM ION, Superoxide dismutase [Mn] | Authors: | Quint, P, Reutzel, R, Mikulski, R, McKenna, R, Silverman, D.N. | Deposit date: | 2005-07-20 | Release date: | 2006-07-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of nitrated human manganese superoxide dismutase: mechanism of inactivation. FREE RADIC.BIOL.MED., 40, 2006
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1CQU
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![BU of 1cqu by Molmil](/molmil-images/mine/1cqu) | |
5MU9
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![BU of 5mu9 by Molmil](/molmil-images/mine/5mu9) | MOA-E-64 complex | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Agglutinin, ... | Authors: | Cordara, G, Manna, D, Krengel, U. | Deposit date: | 2017-01-12 | Release date: | 2017-07-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Family of Papain-Like Fungal Chimerolectins with Distinct Ca(2+)-Dependent Activation Mechanism. Biochemistry, 56, 2017
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6RV3
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![BU of 6rv3 by Molmil](/molmil-images/mine/6rv3) | Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | Authors: | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2019-05-30 | Release date: | 2019-08-07 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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