PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

ROCK2 IN COMPLEX WITH COMPOUND 12
分子名称:	Rho-associated protein kinase 2, ~{N}-[(1~{R})-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-yl-piperidine-1-carboxamide
著者	Maillard, M.C.
登録日	2021-07-16
公開日	2022-07-27
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's Disease. J.Med.Chem., 65, 2022

Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor
分子名称:	(2~{S})-2-(2-fluorophenyl)-2-[4-(2-methylpyrimidin-5-yl)phenyl]-~{N}-oxidanyl-ethanamide, Histone deacetylase 4, SODIUM ION, ...
著者	Luckhurst, C.A, Maillard, M.C, Dominguez, C.
登録日	2018-03-13
公開日	2018-12-05
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.15 Å)
主引用文献	Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor. Bioorg. Med. Chem. Lett., 29, 2019