1EJN
| UROKINASE PLASMINOGEN ACTIVATOR B-CHAIN INHIBITOR COMPLEX | 分子名称: | N-(1-ADAMANTYL)-N'-(4-GUANIDINOBENZYL)UREA, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | 著者 | Sperl, S, Jacob, U, Arroyo de Prada, N, Stuerzebecher, J, Wilhelm, O.G, Bode, W, Magdolen, V, Huber, R, Moroder, L. | 登録日 | 2000-04-22 | 公開日 | 2000-05-17 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | (4-aminomethyl)phenylguanidine derivatives as nonpeptidic highly selective inhibitors of human urokinase. Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
5MS4
| Kallikrein-related peptidase 8 leupeptin inhibitor complex | 分子名称: | CALCIUM ION, Kallikrein-8, LEUPEPTIN, ... | 著者 | Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. | 登録日 | 2016-12-30 | 公開日 | 2018-01-17 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin. Sci Rep, 8, 2018
|
|
4NFF
| Human kallikrein-related peptidase 2 in complex with PPACK | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Kallikrein-2 | 著者 | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | 登録日 | 2013-10-31 | 公開日 | 2014-10-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
|
|
4NFE
| Human kallikrein-related peptidase 2 in complex with benzamidine | 分子名称: | BENZAMIDINE, Kallikrein-2, SULFATE ION | 著者 | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | 登録日 | 2013-10-31 | 公開日 | 2014-10-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
|
|
5MS3
| Kallikrein-related peptidase 8 calcium complex | 分子名称: | CALCIUM ION, Kallikrein-8 | 著者 | Debela, M, Magdolen, V, Skala, W, Bode, W, Brandstetter, H, Goettig, P. | 登録日 | 2016-12-30 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Specificity profiles and antagonistic Ca2+ and Zn2+ regulation of human KLK8/neuropsin activity by modules identified in crystal structures To Be Published
|
|
5LPE
| Kallikrein-related peptidase 10 complex with Zn2+ | 分子名称: | Kallikrein-10, SULFATE ION, ZINC ION | 著者 | Goettig, P, Debela, M, Magdolen, V, Bode, W, Brandstetter, H. | 登録日 | 2016-08-12 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10. Biol.Chem., 397, 2016
|
|
5LPF
| Kallikrein-related peptidase 10 | 分子名称: | Kallikrein-10, SULFATE ION | 著者 | Goettig, P, Debela, M, Magdolen, V, Bode, W, Brandstetter, H. | 登録日 | 2016-08-12 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10. Biol.Chem., 397, 2016
|
|
2QXG
| Crystal Structure of Human Kallikrein 7 in Complex with Ala-Ala-Phe-chloromethylketone | 分子名称: | Kallikrein-7, L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide | 著者 | Debela, M, Hess, P, Magdolen, V, Bode, W, Steiner, T, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2QXH
| Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone | 分子名称: | Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide | 著者 | Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2QXJ
| Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone and Copper | 分子名称: | COPPER (II) ION, Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide | 著者 | Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2QXI
| High resolution structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone | 分子名称: | Kallikrein-7, N-(3-carboxypropanoyl)-L-alanyl-L-alanyl-N-[(2S,3S)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]-L-prolinamide | 著者 | Debela, M, Hess, P, Magdolen, V, Schechter, N.M, Bode, W, Goettig, P. | 登録日 | 2007-08-11 | 公開日 | 2008-01-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|