8JF5
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![BU of 8jf5 by Molmil](/molmil-images/mine/8jf5) | Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAS1440 | 分子名称: | 4-[5-[(3~{R})-3-azanylpyrrolidin-1-yl]carbonyl-2-[2-fluoranyl-4-(2-methyl-2-oxidanyl-propyl)phenyl]phenyl]-2-fluoranyl-benzenecarbonitrile, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Fukushima, H, Machida, T, Yamashita, S, Suzuki, T. | 登録日 | 2023-05-17 | 公開日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | TAS1440, a histone H3 competitive LSD1 inhibitor, activates both TGF-beta and notch signaling pathways via INSM1 dissociation in neuroendocrine small cell lung cancer To Be Published
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