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PDB: 89 件

3RV7
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Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Isopropyl R-Group
分子名称: 3-{[(1Z)-1-carboxy-3-methylbut-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI
著者Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-05-06
公開日2012-05-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 51, 2012
3ST6
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Structure of a M. tuberculosis Synthase, MbtI, in Complex with an Isochorismate Analogue Inhibitor
分子名称: 3-[(1-carboxyethenyl)oxy]-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI
著者Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-07-08
公開日2012-05-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis
Biochemistry, 51, 2012
3R88
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Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS145)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-4,5-dimethoxybenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S.
登録日2011-03-23
公開日2012-09-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3QS8
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Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS174)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-benzylbenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-20
公開日2012-08-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3QQS
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BU of 3qqs by Molmil
Anthranilate phosphoribosyltransferase (TRPD) from Mycobacterium tuberculosis (complex with inhibitor ACS172)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2,2'-iminodibenzoic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-16
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3R6C
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BU of 3r6c by Molmil
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 8-methoxyphenanthro[3,4-d][1,3]dioxole-5,6-dicarboxylic acid, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-03-21
公開日2012-09-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
5BYT
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PRPP complexed with a single Mg in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-11
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
3QR9
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BU of 3qr9 by Molmil
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (apo structure)
分子名称: Anthranilate phosphoribosyltransferase, GLYCEROL
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-17
公開日2011-06-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
5BO3
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BU of 5bo3 by Molmil
Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: 2-[(2-carboxyphenyl)amino]-5-(4-phosphonobutoxy)benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-05-27
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP.
To be Published
5C2L
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BU of 5c2l by Molmil
Magnesium soaked into the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
分子名称: Anthranilate phosphoribosyltransferase, IMIDAZOLE, MAGNESIUM ION
著者Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-06-16
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献Binding and mimicking of the phosphate-rich substrate, PRPP
To Be Published
3QSA
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BU of 3qsa by Molmil
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor TAMU-A7)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione, Anthranilate phosphoribosyltransferase, ...
著者Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2011-02-20
公開日2012-08-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Inhibition of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase by blocking of an active site entrance tunnel.
To be Published
2C1S
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BU of 2c1s by Molmil
X-ray structure of biotin binding protein from chicken
分子名称: BIOTIN BINDING PROTEIN A, BIOTIN-D-SULFOXIDE
著者Hytonen, V.P, Niskanen, E.A, Maatta, J.A.E, Huuskonen, J, Helttunen, K.J, Halling, K.K, Slotte, J.P, Nordlund, H.R, Rissanen, K, Johnson, M.S, Salminen, T.A, Kulomaa, M.S, Laitinen, O.H, Airenne, T.T.
登録日2005-09-19
公開日2007-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Characterization of a Novel Chicken Biotin-Binding Protein a (Bbp-A).
Bmc Struct.Biol., 7, 2007
2C1Q
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BU of 2c1q by Molmil
X-ray structure of biotin binding protein from chicken
分子名称: BIOTIN, BIOTIN BINDING PROTEIN A, GLYCEROL
著者Hytonen, V.P, Niskanen, E.A, Maatta, J.A.E, Huuskonen, J, Helttunen, K.J, Halling, K.K, Slotte, J.P, Nordlund, H.R, Rissanen, K, Johnson, M.S, Salminen, T.A, Kulomaa, M.S, Laitinen, O.H, Airenne, T.T.
登録日2005-09-19
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Characterization of a Novel Chicken Biotin-Binding Protein a (Bbp-A).
Bmc Struct.Biol., 7, 2007
1PT6
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BU of 1pt6 by Molmil
I domain from human integrin alpha1-beta1
分子名称: GLYCEROL, Integrin alpha-1, MAGNESIUM ION
著者Nymalm, Y, Puranen, J.S, Nyholm, T.K.M, Kapyla, J, Kidron, H, Pentikainen, O, Airenne, T.T, Heino, J, Slotte, J.P, Johnson, M.S, Salminen, T.A.
登録日2003-06-23
公開日2004-04-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Jararhagin-derived RKKH peptides induce structural changes in alpha1I domain of human integrin alpha1beta1.
J.Biol.Chem., 279, 2004
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