8B1E
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![BU of 8b1e by Molmil](/molmil-images/mine/8b1e) | DtpB-Nb132-AQ | Descriptor: | ALA-GLN, DECANE, DODECANE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B1F
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![BU of 8b1f by Molmil](/molmil-images/mine/8b1f) | DtpB-Nb132-AV | Descriptor: | ALA-VAL, DECANE, DODECANE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B1G
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![BU of 8b1g by Molmil](/molmil-images/mine/8b1g) | DtpB-Nb132-AW | Descriptor: | ALA-TRP, DECANE, DODECANE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B1I
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![BU of 8b1i by Molmil](/molmil-images/mine/8b1i) | DtpB-Nb132-MS | Descriptor: | DECANE, DODECANE, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B1J
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![BU of 8b1j by Molmil](/molmil-images/mine/8b1j) | DtpB-Nb132-SL | Descriptor: | DECANE, DODECANE, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B1C
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![BU of 8b1c by Molmil](/molmil-images/mine/8b1c) | DtpB-Nb132-ALA | Descriptor: | ALA-LEU-ALA, DECANE, DODECANE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B18
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![BU of 8b18 by Molmil](/molmil-images/mine/8b18) | DtpB-Nb132-AF | Descriptor: | ALA-PHE, DECANE, DODECANE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B17
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![BU of 8b17 by Molmil](/molmil-images/mine/8b17) | DtpB-Nb132-AWA | Descriptor: | ALA-TRP-ALA, DECANE, DODECANE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B1H
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![BU of 8b1h by Molmil](/molmil-images/mine/8b1h) | DtpB-Nb132-KV | Descriptor: | DECANE, DODECANE, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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8B19
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![BU of 8b19 by Molmil](/molmil-images/mine/8b19) | DtpB-Nb132-AFA | Descriptor: | ALA-PHE-ALA, DECANE, DODECANE, ... | Authors: | Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C. | Deposit date: | 2022-09-09 | Release date: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023
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6ZN3
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![BU of 6zn3 by Molmil](/molmil-images/mine/6zn3) | Plasmodium facliparum glideosome trimeric sub-complex | Descriptor: | Myosin A tail domain interacting protein, Myosin essential light chain ELC, Myosin-A | Authors: | Pazicky, S, Loew, C. | Deposit date: | 2020-07-06 | Release date: | 2020-10-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural role of essential light chains in the apicomplexan glideosome. Commun Biol, 3, 2020
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5MMT
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![BU of 5mmt by Molmil](/molmil-images/mine/5mmt) | |
8CNI
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![BU of 8cni by Molmil](/molmil-images/mine/8cni) | PHT1 in the outward facing conformation, bound to Sb27 | Descriptor: | Solute carrier family 15 member 4, Sybody 27 | Authors: | Custodio, T, Killer, M, Loew, C. | Deposit date: | 2023-02-23 | Release date: | 2023-09-27 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Molecular basis of TASL recruitment by the peptide/histidine transporter 1, PHT1. Nat Commun, 14, 2023
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4DT4
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![BU of 4dt4 by Molmil](/molmil-images/mine/4dt4) | |
7OXG
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![BU of 7oxg by Molmil](/molmil-images/mine/7oxg) | ttSlyD FKBP domain with M8A pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, CHLORIDE ION, IMIDAZOLE, ... | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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6EIA
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![BU of 6eia by Molmil](/molmil-images/mine/6eia) | PepTSt in complex with HEPES (100 mM) | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | Deposit date: | 2017-09-18 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
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7OXI
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![BU of 7oxi by Molmil](/molmil-images/mine/7oxi) | ttSlyD with W4A pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7OXH
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![BU of 7oxh by Molmil](/molmil-images/mine/7oxh) | ttSlyD with pseudo-wild-type S2 peptide | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 30S ribosomal protein S2, CHLORIDE ION, ... | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7OXK
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![BU of 7oxk by Molmil](/molmil-images/mine/7oxk) | ttSlyD with W4K pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, Peptidyl-prolyl cis-trans isomerase | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7OXJ
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![BU of 7oxj by Molmil](/molmil-images/mine/7oxj) | ttSlyD with M8A pseudo-wild-type S2 peptide | Descriptor: | 30S ribosomal protein S2, CHLORIDE ION, Fragment of 30S ribosomal protein S2 peptide, ... | Authors: | Pazicky, S, Lei, J, Loew, C. | Deposit date: | 2021-06-22 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Impact of distant peptide substrate residues on enzymatic activity of SlyD. Cell.Mol.Life Sci., 79, 2022
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7PMW
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![BU of 7pmw by Molmil](/molmil-images/mine/7pmw) | HsPepT1 bound to Ala-Phe in the outward facing occluded conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-03 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PMX
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![BU of 7pmx by Molmil](/molmil-images/mine/7pmx) | HsPepT1 bound to Ala-Phe in the outward facing open conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-03 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PMY
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![BU of 7pmy by Molmil](/molmil-images/mine/7pmy) | HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation | Descriptor: | ALA-PHE, Solute carrier family 15 member 2 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-04 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PN1
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![BU of 7pn1 by Molmil](/molmil-images/mine/7pn1) | Apo HsPepT1 in the outward facing open conformation | Descriptor: | Solute carrier family 15 member 1 | Authors: | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | Deposit date: | 2021-09-04 | Release date: | 2021-10-20 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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6TJ6
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![BU of 6tj6 by Molmil](/molmil-images/mine/6tj6) | |