Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 200 results

3VA6
DownloadVisualize
BU of 3va6 by Molmil
Crystal Structure of the extracellular domain of the putative hybrid two component system BT4673 from B. thetaiotaomicron
Descriptor: Two-component system sensor histidine kinase
Authors:Zhang, Z, Liu, Q, Hendrickson, W.A.
Deposit date:2011-12-28
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Extraellular Domain Structures of Two Potential Saccharide-sensing Two-component Systems from a Human Gut Symbiont
To be Published
3VA9
DownloadVisualize
BU of 3va9 by Molmil
Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain
Descriptor: CHLORIDE ION, Sensor histidine kinase
Authors:Zhang, Z, Liu, Q, Hendrickson, W.A.
Deposit date:2011-12-29
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Rhodopseudomonas palustris histidine kinase HK9 sensor domain
To be Published
3V9F
DownloadVisualize
BU of 3v9f by Molmil
Crystal Structure of the extracellular domain of the putative hybrid two component system BT3049 from B. thetaiotaomicron
Descriptor: Two-component system sensor histidine kinase/response regulator, hybrid (One-component system)
Authors:Zhang, Z, Liu, Q, Hendrickson, W.A.
Deposit date:2011-12-27
Release date:2012-03-14
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont.
Febs J., 281, 2014
5K0X
DownloadVisualize
BU of 5k0x by Molmil
Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2541
Descriptor: (7S)-7-amino-N-[(4-fluorophenyl)methyl]-8-oxo-2,9,16,18,21-pentaazabicyclo[15.3.1]henicosa-1(21),17,19-triene-20-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
Authors:McIver, A.L, Zhang, W, Liu, Q, Jiang, X, Stashko, M.A, Nichols, J, Miley, M.J, Norris-Drouin, J, Machius, M, DeRyckere, D, Wood, E, Graham, D.K, Earp, H.S, Kireev, D, Frye, S.V, Wang, X.
Deposit date:2016-05-17
Release date:2017-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.231 Å)
Cite:Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.
ChemMedChem, 12, 2017
2ITG
DownloadVisualize
BU of 2itg by Molmil
CATALYTIC DOMAIN OF HIV-1 INTEGRASE: ORDERED ACTIVE SITE IN THE F185H CONSTRUCT
Descriptor: HUMAN IMMUNODEFICIENCY VIRUS-1 INTEGRASE
Authors:Bujacz, G, Alexandratos, J, Wlodawer, A, Zhou-Liu, Q, Clement-Mella, C.
Deposit date:1996-09-13
Release date:1997-03-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The catalytic domain of human immunodeficiency virus integrase: ordered active site in the F185H mutant.
FEBS Lett., 398, 1996
4F35
DownloadVisualize
BU of 4f35 by Molmil
Crystal Structure of a bacterial dicarboxylate/sodium symporter
Descriptor: CITRIC ACID, SODIUM ION, Transporter, ...
Authors:Mancusso, R.L, Gregorio, G.G, Liu, Q, Wang, D.N.
Deposit date:2012-05-08
Release date:2012-10-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.196 Å)
Cite:Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter.
Nature, 491, 2012
8ENA
DownloadVisualize
BU of 8ena by Molmil
Thaumatin native-SAD structure determined at 5 keV with a helium environmet
Descriptor: Thaumatin-1
Authors:Karasawa, A, Andi, B, Ruchs, M.R, Shi, W, McSweeney, S, Hendrickson, W.A, Liu, Q.
Deposit date:2022-09-29
Release date:2022-11-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multi-crystal native-SAD phasing at 5 keV with a helium environment.
Iucrj, 9, 2022
8EN9
DownloadVisualize
BU of 8en9 by Molmil
TehA native-SAD structure determined at 5 keV with a helium environment
Descriptor: CHLORIDE ION, SODIUM ION, Tellurite resistance protein TehA homolog, ...
Authors:Karasawa, A, Andi, B, Ruchs, M.R, Shi, W, McSweeney, S, Hendrickson, W.A, Liu, Q.
Deposit date:2022-09-29
Release date:2022-11-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Multi-crystal native-SAD phasing at 5 keV with a helium environment.
Iucrj, 9, 2022
6ITJ
DownloadVisualize
BU of 6itj by Molmil
Crystal structure of FGFR1 kinase domain in complex with compound 3
Descriptor: 4-azanyl-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-phenyl-6~{H}-pyrazolo[3,4-d]pyridazin-7-one, Fibroblast growth factor receptor 1
Authors:Xu, Y, Liu, Q.
Deposit date:2018-11-23
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.
J.Med.Chem., 62, 2019
6IUP
DownloadVisualize
BU of 6iup by Molmil
Crystal structure of FGFR4 kinase domain in complex with compound 5
Descriptor: DIMETHYL SULFOXIDE, Fibroblast growth factor receptor 4, N-{4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2H-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}prop-2-enamide
Authors:Xu, Y, Liu, Q.
Deposit date:2018-11-29
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.
J.Med.Chem., 62, 2019
6NQ8
DownloadVisualize
BU of 6nq8 by Molmil
Crystal structure of YetJ mutant from Bacillus Subtilis - D171E
Descriptor: Uncharacterized protein YetJ
Authors:Guo, G, Chang, Y, Liu, Q.
Deposit date:2019-01-19
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ion and pH Sensitivity of a TMBIM Ca2+Channel.
Structure, 27, 2019
6NQ9
DownloadVisualize
BU of 6nq9 by Molmil
Crystal structure of YetJ mutant from Bacillus Subtilis - D195E
Descriptor: Uncharacterized protein YetJ
Authors:Guo, G, Chang, Y, Liu, Q.
Deposit date:2019-01-19
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ion and pH Sensitivity of a TMBIM Ca2+Channel.
Structure, 27, 2019
6IUO
DownloadVisualize
BU of 6iuo by Molmil
Crystal structure of FGFR4 kinase domain in complex with a covalent inhibitor
Descriptor: Fibroblast growth factor receptor 4, N-({4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2H-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}methyl)prop-2-enamide
Authors:Xu, Y, Liu, Q.
Deposit date:2018-11-29
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design.
J.Med.Chem., 62, 2019
6NQ7
DownloadVisualize
BU of 6nq7 by Molmil
Crystal structure of YetJ from Bacillus Subtilis crystallized in lipidic cubic phase
Descriptor: GADOLINIUM ATOM, Uncharacterized protein YetJ
Authors:Guo, G, Chang, Y, Liu, Q.
Deposit date:2019-01-19
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ion and pH Sensitivity of a TMBIM Ca2+Channel.
Structure, 27, 2019
2IMT
DownloadVisualize
BU of 2imt by Molmil
The X-ray Structure of a Bak Homodimer Reveals an Inhibitory Zinc Binding Site
Descriptor: Apoptosis regulator BAK, ZINC ION
Authors:Moldoveanu, T, Liu, Q, Tocilj, A, Watson, M, Shore, G.C, Gehring, K.B.
Deposit date:2006-10-04
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site.
Mol.Cell, 24, 2006
2IMS
DownloadVisualize
BU of 2ims by Molmil
The X-ray Structure of a Bak Homodimer Reveals an Inhibitory Zinc Binding Site
Descriptor: Apoptosis regulator BAK, ZINC ION
Authors:Moldoveanu, T, Liu, Q, Tocilj, A, Watson, M, Shore, G.C, Gehring, K.B.
Deposit date:2006-10-04
Release date:2006-12-26
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:The X-Ray Structure of a BAK Homodimer Reveals an Inhibitory Zinc Binding Site
Mol.Cell, 24, 2006
5EKE
DownloadVisualize
BU of 5eke by Molmil
Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (F215A mutant)
Descriptor: MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501
Authors:Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2015-11-03
Release date:2016-01-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
Nat Commun, 7, 2016
5EKP
DownloadVisualize
BU of 5ekp by Molmil
Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (WT)
Descriptor: MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501
Authors:Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2015-11-03
Release date:2016-01-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.194 Å)
Cite:Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
Nat Commun, 7, 2016
9ATW
DownloadVisualize
BU of 9atw by Molmil
Structure of biofilm-forming functional amyloid PSMa1 from Staphylococcus aureus
Descriptor: Phenol-soluble modulin alpha 1 peptide
Authors:Hansen, K.H, Byeon, C.H, Liu, Q, Drace, T, Boesen, T, Conway, J.F, Andreasen, M, Akbey, U.
Deposit date:2024-02-27
Release date:2024-08-07
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of biofilm-forming functional amyloid PSM alpha 1 from Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 121, 2024
8X6G
DownloadVisualize
BU of 8x6g by Molmil
Cryo-EM structure of Staphylococcus aureus sigB-dependent RNAP-promoter open complex
Descriptor: DNA (70-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yuan, L, Xu, L, Liu, Q, Feng, Y.
Deposit date:2023-11-21
Release date:2024-06-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
8X6F
DownloadVisualize
BU of 8x6f by Molmil
Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex
Descriptor: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Yuan, L, Xu, L, Liu, Q, Feng, Y.
Deposit date:2023-11-21
Release date:2024-06-05
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
6EGE
DownloadVisualize
BU of 6ege by Molmil
Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor
Descriptor: Interleukin-1 receptor-associated kinase 4, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide
Authors:Ferrao, R, Liu, Q, Wu, H.
Deposit date:2018-08-19
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019
3QCQ
DownloadVisualize
BU of 3qcq by Molmil
Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-(3-Amino-1H-indazol-6-yl)-N4-ethyl-2,4-pyrimidinediamine
Descriptor: 3-phosphoinositide-dependent protein kinase 1, 6-(3-amino-2H-indazol-6-yl)-N~4~-ethylpyrimidine-2,4-diamine, GLYCEROL, ...
Authors:Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M.
Deposit date:2011-01-17
Release date:2011-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors.
J.Med.Chem., 54, 2011
3QCY
DownloadVisualize
BU of 3qcy by Molmil
Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 4-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-N-phenyl-2-morpholinecarboxamide
Descriptor: (2S)-4-[2-amino-6-(3-amino-2H-indazol-6-yl)pyrimidin-4-yl]-N-phenylmorpholine-2-carboxamide, 3-phosphoinositide-dependent protein kinase 1, GLYCEROL, ...
Authors:Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M.
Deposit date:2011-01-17
Release date:2011-03-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors.
J.Med.Chem., 54, 2011
3QCX
DownloadVisualize
BU of 3qcx by Molmil
Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-{2-Amino-6-[(3R)-3-methyl-4-morpholinyl]-4-pyrimidinyl}-1H-indazol-3-amine
Descriptor: 3-phosphoinositide-dependent protein kinase 1, 6-{2-amino-6-[(3R)-3-methylmorpholin-4-yl]pyrimidin-4-yl}-2H-indazol-3-amine, GLYCEROL, ...
Authors:Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M.
Deposit date:2011-01-17
Release date:2011-03-09
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors.
J.Med.Chem., 54, 2011

224004

건을2024-08-21부터공개중

PDB statisticsPDBj update infoContact PDBjnumon