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PDB: 3 results

4P66
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BU of 4p66 by Molmil
Electrostatics of Active Site Microenvironments of E. coli DHFR
Descriptor: CALCIUM ION, Dihydrofolate reductase, METHOTREXATE, ...
Authors:Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J.
Deposit date:2014-03-21
Release date:2014-07-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase.
J.Am.Chem.Soc., 136, 2014
4P68
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BU of 4p68 by Molmil
Electrostatics of Active Site Microenvironments for E. coli DHFR
Descriptor: ACETATE ION, CALCIUM ION, Dihydrofolate reductase, ...
Authors:Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J.
Deposit date:2014-03-22
Release date:2014-07-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase.
J.Am.Chem.Soc., 136, 2014
4GH8
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BU of 4gh8 by Molmil
Crystal structure of a 'humanized' E. coli dihydrofolate reductase
Descriptor: CALCIUM ION, Dihydrofolate reductase, METHOTREXATE, ...
Authors:French, J.B, Liu, C.T, Hanoian, P, Pringle, T.H, Hammes-Schiffer, S, Benkovic, S.J.
Deposit date:2012-08-07
Release date:2013-06-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Functional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humans.
Proc.Natl.Acad.Sci.USA, 110, 2013

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