1EPS
 
 | | STRUCTURE AND TOPOLOGICAL SYMMETRY OF THE GLYPHOSPHATE 5-ENOL-PYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE: A DISTINCTIVE PROTEIN FOLD | | 分子名称: | 5-ENOL-PYRUVYL-3-PHOSPHATE SYNTHASE | | 著者 | Stallings, W.C, Abdel-Meguid, S.S, Lim, L.W, Shieh, H.-S, Dayringer, H.E, Leimgruber, N.K, Stegeman, R.A, Anderson, K.S, Sikorski, J.A, Padgette, S.R, Kishore, G.M. | | 登録日 | 1991-04-05 | | 公開日 | 1993-07-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and topological symmetry of the glyphosate target 5-enolpyruvylshikimate-3-phosphate synthase: a distinctive protein fold.
Proc.Natl.Acad.Sci.USA, 88, 1991
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4UFT
 | | Structure of the helical Measles virus nucleocapsid | | 分子名称: | 5'-R(*CP*CP*CP*CP*CP*CP)-3', NUCLEOPROTEIN | | 著者 | Gutsche, I, Desfosses, A, Effantin, G, Ling, W.L, Haupt, M, Ruigrok, R.W.H, Sachse, C, Schoehn, G. | | 登録日 | 2015-03-19 | | 公開日 | 2015-04-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Near-Atomic Cryo-Em Structure of the Helical Measles Virus Nucleocapsid.
Science, 348, 2015
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3POS
 | | Crystal structure of the globular domain of human calreticulin | | 分子名称: | CALCIUM ION, Calreticulin | | 著者 | Chouquet, A, Paidassi, H, Ling, W.-L, Frachet, P, Houen, G, Arlaud, G.J, Gaboriaud, C. | | 登録日 | 2010-11-23 | | 公開日 | 2011-03-09 | | 最終更新日 | 2017-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | X-ray structure of the human calreticulin globular domain reveals a Peptide-binding area and suggests a multi-molecular mechanism
Plos One, 6, 2011
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8A1R
 | | cryo-EM structure of thioredoxin glutathione reductase in complex with a non-competitive inhibitor | | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-[3-[[[(1~{R},2~{R},3~{R},5~{S})-2,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl]amino]methyl]indol-1-yl]oxane-3,4,5-triol, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase | | 著者 | Ardini, M, Angelucci, F, Fata, F, Gabriele, F, Effantin, G, Ling, W, Williams, D.L, Petukhova, V.Z, Petukhov, P.A. | | 登録日 | 2022-06-01 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
Nat Commun, 14, 2023
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8APL
 | | Vaccinia virus DNA helicase D5 residues 323-785 hexamer with bound DNA processed in C6 | | 分子名称: | Primase D5 | | 著者 | Burmeister, W.P, Hutin, S, Ling, W.L, Grimm, C, Schoehn, G. | | 登録日 | 2022-08-10 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | The Vaccinia Virus DNA Helicase Structure from Combined Single-Particle Cryo-Electron Microscopy and AlphaFold2 Prediction.
Viruses, 14, 2022
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8APM
 | | Vaccinia virus DNA helicase D5 residues 323-785 hexamer with bound DNA processed in C1 | | 分子名称: | DNA (5'-D(P*CP*CP*GP*AP*AP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*TP*TP*CP*GP*G)-3'), Primase D5 | | 著者 | Burmeister, W.P, Hutin, S, Ling, W.L, Grimm, C, Schoehn, G. | | 登録日 | 2022-08-10 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | The Vaccinia Virus DNA Helicase Structure from Combined Single-Particle Cryo-Electron Microscopy and AlphaFold2 Prediction.
Viruses, 14, 2022
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6ZHJ
 | | 3D electron diffraction structure of thermolysin from Bacillus thermoproteolyticus | | 分子名称: | CALCIUM ION, Thermolysin, ZINC ION | | 著者 | Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P. | | 登録日 | 2020-06-23 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3.26 Å) | | 主引用文献 | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
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6ZHN
 | | 3D electron diffraction structure of thaumatin from Thaumatococcus daniellii | | 分子名称: | CHLORIDE ION, Thaumatin-1 | | 著者 | Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P. | | 登録日 | 2020-06-23 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.76 Å) | | 主引用文献 | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
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6ZHB
 | | 3D electron diffraction structure of bovine insulin | | 分子名称: | Insulin, ZINC ION | | 著者 | Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G, Ling, W.L, Abrahams, J.P. | | 登録日 | 2020-06-22 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3.25 Å) | | 主引用文献 | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
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6ZI8
 | | X-ray diffraction structure of bovine insulin at 2.3 A resolution | | 分子名称: | CHLORIDE ION, Insulin, ZINC ION | | 著者 | Housset, D, Ling, W.L, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G. | | 登録日 | 2020-06-25 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
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6OS8
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1MNG
 | | STRUCTURE-FUNCTION IN E. COLI IRON SUPEROXIDE DISMUTASE: COMPARISONS WITH THE MANGANESE ENZYME FROM T. THERMOPHILUS | | 分子名称: | AZIDE ION, MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE | | 著者 | Lah, M.S, Dixon, M, Pattridge, K.A, Stallings, W.C, Fee, J.A, Ludwig, M.L. | | 登録日 | 1994-07-13 | | 公開日 | 1994-10-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-function in Escherichia coli iron superoxide dismutase: comparisons with the manganese enzyme from Thermus thermophilus.
Biochemistry, 34, 1995
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6U47
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3MDS
 | | MAGANESE SUPEROXIDE DISMUTASE FROM THERMUS THERMOPHILUS | | 分子名称: | MANGANESE (III) ION, MANGANESE SUPEROXIDE DISMUTASE | | 著者 | Ludwig, M.L, Metzger, A.L, Pattridge, K.A, Stallings, W.C. | | 登録日 | 1993-10-20 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Manganese superoxide dismutase from Thermus thermophilus. A structural model refined at 1.8 A resolution.
J.Mol.Biol., 219, 1991
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3HC8
 | | Investigation of Aminopyridiopyrazinones as PDE5 Inhibitors: Evaluation of Modifications to the Central Ring System. | | 分子名称: | 6-(6-methoxypyridin-3-yl)-2-[(2-morpholin-4-ylethyl)amino]-4-(2-propoxyethyl)pyrido[2,3-b]pyrazin-3(4H)-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Hughes, R.O, Stallings, W.C, Cubbage, J.W, Williams, J.M. | | 登録日 | 2009-05-05 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system.
Bioorg.Med.Chem.Lett., 19, 2009
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6Q1W
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6Q22
 | | Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad | | 分子名称: | Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad, PENTAETHYLENE GLYCOL | | 著者 | Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. | | 登録日 | 2019-08-06 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-05-20 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
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6Q25
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6OVV
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6OSD
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6OV9
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6OVS
 | | Coiled-coil Trimer with Glu:Tyr:Lys Triad | | 分子名称: | Coiled-coil Trimer with Glu:Tyr:Lys Triad, PENTAETHYLENE GLYCOL | | 著者 | Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. | | 登録日 | 2019-05-08 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-05-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
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6COX
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3LN0
 | | Structure of compound 5c-S bound at the active site of COX-2 | | 分子名称: | (2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kiefer, J.R, Kurumbail, R.G, Stallings, W.C, Pawlitz, J.L. | | 登録日 | 2010-02-01 | | 公開日 | 2010-10-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life.
Bioorg.Med.Chem.Lett., 20, 2010
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3LN1
 | | Structure of celecoxib bound at the COX-2 active site | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE, ... | | 著者 | Kiefer, J.R, Kurumbail, R.G, Stallings, W.C, Pawlitz, J.L. | | 登録日 | 2010-02-01 | | 公開日 | 2010-10-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life.
Bioorg.Med.Chem.Lett., 20, 2010
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