7EU5
| Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with tricyclic small molecule inhibitor JBSNF-000107 | 分子名称: | 6-fluoranyl-10-methyl-1,10-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-11-imine, Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Swaminathan, S, Gosu, R, Birudukota, S, Kandan, S, Vaithilingam, K. | 登録日 | 2021-05-16 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.731 Å) | 主引用文献 | Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep, 12, 2022
|
|
7ET7
| Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with tricyclic small molecule inhibitor JBSNF-000028 | 分子名称: | 10-methyl-1,10-diazatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-11-imine, Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Swaminathan, S, Gosu, R, Birudukota, S, Kandan, S, Vaithilingam, K. | 登録日 | 2021-05-12 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep, 12, 2022
|
|
3ZGQ
| Crystal structure of human interferon-induced protein IFIT5 | 分子名称: | DI(HYDROXYETHYL)ETHER, INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 | 著者 | Katibah, G.E, Lee, H.J, Huizar, J.P, Vogan, J.M, Alber, T, Collins, K. | 登録日 | 2012-12-19 | 公開日 | 2013-01-23 | 最終更新日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | TRNA Binding, Structure, and Localization of the Human Interferon-Induced Protein Ifit5. Mol.Cell, 49, 2013
|
|
1XZ9
| Structure of AF-6 PDZ domain | 分子名称: | Afadin | 著者 | Joshi, M, Boisguerin, P, Leitner, D, Volkmer-Engert, R, Moelling, K, Schade, M, Schmieder, P, Krause, G, Oschkinat, H. | 登録日 | 2004-11-12 | 公開日 | 2005-11-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery of low-molecular-weight ligands for the AF6 PDZ domain. Angew.Chem.Int.Ed.Engl., 45, 2006
|
|
2LPI
| NMR structure of a monomeric mutant (A72R) of major ampullate spidroin 1 N-terminal domain | 分子名称: | Major ampullate spidroin 1 | 著者 | Jaudzems, K, Nordling, K, Landreh, M, Rising, A, Askarieh, G, Knight, S.D, Johansson, J. | 登録日 | 2012-02-14 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain. J.Mol.Biol., 422, 2012
|
|
2LTH
| NMR structure of major ampullate spidroin 1 N-terminal domain at pH 5.5 | 分子名称: | Major ampullate spidroin 1 | 著者 | Otikovs, M, Jaudzems, K, Nordling, K, Landreh, M, Rising, A, Askarieh, G, Knight, S, Johansson, J. | 登録日 | 2012-05-25 | 公開日 | 2013-11-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation. Nat Commun, 5, 2014
|
|
2LPJ
| NMR structure of major ampullate spidroin 1 N-terminal domain at pH 7.2 | 分子名称: | Major ampullate spidroin 1 | 著者 | Jaudzems, K, Nordling, K, Landreh, M, Rising, A, Askarieh, G, Knight, S.D, Johansson, J. | 登録日 | 2012-02-14 | 公開日 | 2012-06-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | pH-Dependent Dimerization of Spider Silk N-Terminal Domain Requires Relocation of a Wedged Tryptophan Side Chain. J.Mol.Biol., 422, 2012
|
|
2MFZ
| NMR structure of C-terminal domain from A. ventricosus minor ampullate spidroin (MiSp) | 分子名称: | Minor ampullate spidroin | 著者 | Otikovs, M, Jaudzems, K, Andersson, M, Chen, G, Landreh, M, Nordling, K, Kronqvist, N, Westermark, P, Jornvall, H, Knight, S, Ridderstrale, Y, Holm, L, Meng, Q, Chesler, M, Johansson, J, Rising, A. | 登録日 | 2013-10-24 | 公開日 | 2014-08-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Carbonic Anhydrase Generates CO2 and H+ That Drive Spider Silk Formation Via Opposite Effects on the Terminal Domains Plos Biol., 12, 2014
|
|
2WKN
| gamma lactamase from Delftia acidovorans | 分子名称: | FORMAMIDASE, ZINC ION | 著者 | Isupov, M.N, Line, K, Gonsalvez, I.S, Gange-Harris, P, Lanzotti, M, Saneei, V, Littlechild, J.A. | 登録日 | 2009-06-16 | 公開日 | 2010-09-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The Structure of Gamma Lactamase from Delftia Acidovorans To be Published
|
|
2VJE
| Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | 分子名称: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | 著者 | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | 登録日 | 2007-12-10 | 公開日 | 2008-05-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Cell Death Differ., 15, 2008
|
|
2VJF
| Crystal Structure of the MDM2-MDMX RING Domain Heterodimer | 分子名称: | CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... | 著者 | Mace, P.D, Linke, K, Smith, C.A, Day, C.L. | 登録日 | 2007-12-10 | 公開日 | 2008-05-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans. Cell Death Differ., 15, 2008
|
|
2X2Q
| Crystal structure of an 'all locked' LNA duplex at 1.9 angstrom resolution | 分子名称: | CACODYLATE ION, COBALT HEXAMMINE(III), LOCKED NUCLEIC ACID DERIVED FROM TRNA SER ACCEPTOR STEM MICROHELIX, ... | 著者 | Eichert, A, Behling, K, Fuerste, J.P, Betzel, C, Erdmann, V.A, Foerster, C. | 登録日 | 2010-01-15 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Crystal Structure of an 'All Locked' Nucleic Acid Duplex. Nucleic Acids Res., 38, 2010
|
|
2KYE
| Solution structure of the pseudouridine modified P6.1 hairpin of human telomerase RNA | 分子名称: | RNA (5'-R(*GP*AP*GP*AP*GP*(PSU)P*(PSU)P*GP*GP*GP*CP*(PSU)P*CP*(PSU)P*C)-3') | 著者 | Kim, N.-K, Theimer, C.A, Mitchell, J.R, Collins, K, Feigon, J. | 登録日 | 2010-05-25 | 公開日 | 2010-06-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res., 38, 2010
|
|
1QHQ
| AURACYANIN, A BLUE COPPER PROTEIN FROM THE GREEN THERMOPHILIC PHOTOSYNTHETIC BACTERIUM CHLOROFLEXUS AURANTIACUS | 分子名称: | CHLORIDE ION, COPPER (II) ION, PROTEIN (AURACYANIN), ... | 著者 | Bond, C.S, Blankenship, R.E, Freeman, H.C, Guss, J.M, Maher, M, Selvaraj, F, Wilce, M.C.J, Willingham, K. | 登録日 | 1999-05-25 | 公開日 | 2001-03-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of auracyanin, a "blue" copper protein from the green thermophilic photosynthetic bacterium Chloroflexus aurantiacus. J.Mol.Biol., 306, 2001
|
|
2LSL
| Solution structure of the C-terminal domain of Tetrahymena telomerase protein p65 | 分子名称: | Telomerase associated protein p65 | 著者 | Singh, M, Wang, Z, Koo, B, Patel, A, Cascio, D, Collins, K, Feigon, J. | 登録日 | 2012-05-01 | 公開日 | 2012-06-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
|
|
2M21
| Solution structure of the Tetrahymena telomerase RNA stem IV terminal loop | 分子名称: | 5'-R(*GP*GP*CP*GP*AP*UP*AP*CP*AP*CP*UP*AP*UP*UP*UP*AP*UP*CP*GP*CP*C)-3' | 著者 | Cash, D.D, Richards, R.J, Wu, H, Trantirek, L, O'Connor, C.M, Feigon, J, Collins, K. | 登録日 | 2012-12-11 | 公開日 | 2013-03-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. Rna, 12, 2006
|
|