6LGT
| Complex structure of HPPD with an inhibitor Y16542 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-(2-chlorophenyl)-6-(1,3-dimethyl-5-oxidanyl-pyrazol-4-yl)carbonyl-1,5-dimethyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, ... | 著者 | Lin, H.Y, Yang, W.C, Yang, G.F. | 登録日 | 2019-12-05 | 公開日 | 2020-10-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.794 Å) | 主引用文献 | Discovery of Novel Pyrazole-Quinazoline-2,4-dione Hybrids as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. J.Agric.Food Chem., 68, 2020
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4Y24
| Complex of human Galectin-1 and TD-139 | 分子名称: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-1 | 著者 | Lin, H.Y, Hsieh, T.J, Lin, C.H. | 登録日 | 2015-02-09 | 公開日 | 2016-04-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors. Sci Rep, 6, 2016
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4Y1V
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4Y1U
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4Y26
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4Y22
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4Y1Z
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4Y1Y
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4Y20
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4Y1X
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6JX9
| Structure of Y17107 complexed HPPD | 分子名称: | 4-hydroxyphenylpyruvate dioxygenase, 5-[(~{Z})-(1,3-dimethyl-5-oxidanylidene-pyrazol-4-ylidene)-oxidanyl-methyl]-2-(phenylmethyl)isoindole-1,3-dione, COBALT (II) ION | 著者 | Lin, H.Y, Yang, G.F. | 登録日 | 2019-04-22 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Pyrazole-Isoindoline-1,3-dione Hybrid: A Promising Scaffold for 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. J.Agric.Food Chem., 67, 2019
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5YWG
| Crystal structure of Arabidopsis thaliana HPPD complexed with Mesotrione | 分子名称: | 2-[(4-methylsulfonyl-2-nitro-phenyl)-oxidanyl-methylidene]cyclohexane-1,3-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Lin, H.Y, Yang, W.C. | 登録日 | 2017-11-29 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | 主引用文献 | Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations. FEBS J., 286, 2019
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7CJK
| Complex structure of AtHPPD with inhibitor Y18093 | 分子名称: | 3-oxidanyl-2-[3,5,6-tris(chloranyl)-4-[(4-chlorophenyl)methylamino]pyridin-2-yl]carbonyl-cyclohex-2-en-1-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Lin, H.Y, Yang, G.F. | 登録日 | 2020-07-11 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Complex structure of AtHPPD with inhibitor Y18093 To Be Published
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7CQR
| Complex structure of HPPD with Y16550 | 分子名称: | 3-(3-chlorophenyl)-6-[(2,5-dimethyl-3-oxidanylidene-1~{H}-pyrazol-4-yl)carbonyl]-1,5-dimethyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Lin, H.Y, Yang, G.F. | 登録日 | 2020-08-11 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.947 Å) | 主引用文献 | Structural insights of 4-Hydrophenylpyruvate dioxygenase inhibition by structurally diverse small molecules Adv Agrochem, 2022
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7CQS
| Complex structure of HPPD with Topramezone | 分子名称: | 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonyl-phenyl]carbonyl-2-methyl-1~{H}-pyrazol-3-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | 著者 | Lin, H.Y, Yang, G.F. | 登録日 | 2020-08-11 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Structural insights of 4-Hydrophenylpyruvate dioxygenase inhibition by structurally diverse small molecules Adv Agrochem, 2022
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7EZQ
| Complex structure of AtHPPD with inhibitor Y15832 | 分子名称: | 4-hydroxyphenylpyruvate dioxygenase, 6-(1,3-dimethyl-5-oxidanyl-pyrazol-4-yl)carbonyl-1,5-dimethyl-3-(2-methylphenyl)quinazoline-2,4-dione, COBALT (II) ION | 著者 | Lin, H.Y, Yang, G.F. | 登録日 | 2021-06-01 | 公開日 | 2022-06-01 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.886 Å) | 主引用文献 | Complex structure of AtHPPD with inhibitor Y18093 To Be Published
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7E0X
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7V6X
| Crystal structure of HPPD complexed with Y18556 | 分子名称: | 4-hydroxyphenylpyruvate dioxygenase, 5-methyl-3-[(2-methylphenyl)methyl]-6-[(1~{R},2~{S})-2-oxidanyl-6-oxidanylidene-cyclohexyl]carbonyl-1,2,3-benzotriazin-4-one, COBALT (II) ION | 著者 | Lin, H.Y, Yang, G.F. | 登録日 | 2021-08-20 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Pharmacophore-Oriented Discovery of Novel 1,2,3-Benzotriazine-4-one Derivatives as Potent 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. J.Agric.Food Chem., 70, 2022
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4XBN
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4XBQ
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4XBL
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5H9Q
| Crystal Structure of Human Galectin-7 in Complex with TD139 | 分子名称: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-7 | 著者 | Hsieh, T.J, Lin, H.Y, Lin, C.H. | 登録日 | 2015-12-29 | 公開日 | 2016-06-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.931 Å) | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors Sci Rep, 6, 2016
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5H9S
| Crystal Structure of Human Galectin-7 in Complex with TAZTDG | 分子名称: | (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, Galectin-7 | 著者 | Hsieh, T.J, Lin, H.Y, Lin, C.H. | 登録日 | 2015-12-29 | 公開日 | 2016-06-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.821 Å) | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors Sci Rep, 6, 2016
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5H9R
| Crystal Structure of Human Galectin-3 CRD in Complex with TAZTDG | 分子名称: | (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, Galectin-3 | 著者 | Hsieh, T.J, Lin, H.Y, Lin, C.H. | 登録日 | 2015-12-29 | 公開日 | 2016-06-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors Sci Rep, 6, 2016
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5H9P
| Crystal Structure of Human Galectin-3 CRD in Complex with TD139 | 分子名称: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-3 | 著者 | Hsieh, T.J, Lin, H.Y, Lin, C.H. | 登録日 | 2015-12-29 | 公開日 | 2016-06-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors Sci Rep, 6, 2016
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