1I73
 
 | | COMPLEX OF PRO-LEU-L-TRP PHOSPHONATE WITH THE CATALITIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | | Descriptor: | CALCIUM ION, NEUTROPHIL COLLAGENASE, THREE RESIDUE PEPTIDE INHIBITOR, ... | | Authors: | Gavuzzo, E, Pochetti, G, Mazza, F, Gallina, C, Gorini, B, D'Alessio, S, Pieper, M, Tschesche, H, Tucker, P.A. | | Deposit date: | 2001-03-07 | | Release date: | 2001-03-21 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.
J.Med.Chem., 43, 2000
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3V0D
 | | Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S) | | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | | Deposit date: | 2011-12-07 | | Release date: | 2012-05-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | A glutamate switch controls voltage-sensitive phosphatase function.
Nat.Struct.Mol.Biol., 19, 2012
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1HA4
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3V0G
 | | Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), form III | | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | | Deposit date: | 2011-12-08 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A glutamate switch controls voltage-sensitive phosphatase function.
Nat.Struct.Mol.Biol., 19, 2012
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1I76
 | | COMPLEX OF 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID (D-TIC DERIVATIVE) WITH T CATALITIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | | Descriptor: | 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID, CALCIUM ION, NEUTROPHIL COLLAGENASE, ... | | Authors: | Gavuzzo, E, Pochetti, G, Mazza, F, Gallina, C, Gorini, B, D'Alessio, S, Pieper, M, Tschesche, H, Tucker, P.A. | | Deposit date: | 2001-03-08 | | Release date: | 2001-03-21 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.
J.Med.Chem., 43, 2000
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1HY0
 | | CRYSTAL STRUCTURE OF WILD TYPE DUCK DELTA 1 CRYSTALLIN (EYE LENS PROTEIN) | | Descriptor: | DELTA CRYSTALLIN I, SULFATE ION | | Authors: | Sampaleanu, L.M, Vallee, F, Slingsby, C, Howell, P.L. | | Deposit date: | 2001-01-17 | | Release date: | 2001-04-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural studies of duck delta 1 and delta 2 crystallin suggest conformational changes occur during catalysis.
Biochemistry, 40, 2001
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2BV2
 | | beta gamma crystallin from Ciona Intestinalis | | Descriptor: | ACETATE ION, CALCIUM ION, CIONA BETAGAMMA-CRYSTALLIN, ... | | Authors: | Shimeld, S.M, Purkiss, A.G, Dirks, R.P.H, Bateman, O.A, Slingsby, C, Lubsen, N.H. | | Deposit date: | 2005-06-21 | | Release date: | 2005-09-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Urochordate Betagamma-Crystallin and the Evolutionary Origin of the Vertebrate Eye Lens.
Curr.Biol., 15, 2005
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3QP5
 | | Crystal structure of CviR bound to antagonist chlorolactone (CL) | | Descriptor: | 4-(4-chlorophenoxy)-N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, CviR transcriptional regulator | | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | | Deposit date: | 2011-02-11 | | Release date: | 2011-03-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.249 Å) | | Cite: | A strategy for antagonizing quorum sensing.
Mol.Cell, 42, 2011
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2BOL
 | | CRYSTAL STRUCTURE AND ASSEMBLY OF TSP36, A METAZOAN SMALL HEAT SHOCK PROTEIN | | Descriptor: | SMALL HEAT SHOCK PROTEIN, SULFATE ION | | Authors: | Stamler, R.J, Kappe, G, Boelens, W.C, Slingsby, C. | | Deposit date: | 2005-04-12 | | Release date: | 2005-09-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Wrapping the Alpha-Crystallin Domain Fold in a Chaperone Assembly.
J.Mol.Biol., 353, 2005
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1A7H
 | | GAMMA S CRYSTALLIN C-TERMINAL DOMAIN | | Descriptor: | GAMMAS CRYSTALLIN | | Authors: | Basak, A.K, Slingsby, C. | | Deposit date: | 1998-03-13 | | Release date: | 1998-05-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | The C-terminal domains of gammaS-crystallin pair about a distorted twofold axis.
Protein Eng., 11, 1998
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1A5D
 | | GAMMAE CRYSTALLIN FROM RAT LENS | | Descriptor: | GAMMAE CRYSTALLIN | | Authors: | Norledge, B.V, Hay, R, Bateman, O.A, Slingsby, C, Driessen, H.P.C. | | Deposit date: | 1998-02-12 | | Release date: | 1998-05-27 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD.
Exp.Eye Res., 65, 1997
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3QP6
 | | Crystal structure of CviR (Chromobacterium violaceum 12472) bound to C6-HSL | | Descriptor: | CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]hexanamide | | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | | Deposit date: | 2011-02-11 | | Release date: | 2011-03-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A strategy for antagonizing quorum sensing.
Mol.Cell, 42, 2011
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2V2U
 | | Structure of Mouse gammaC-crystallin | | Descriptor: | GAMMA CRYSTALLIN C | | Authors: | Purkiss, A.G, Bateman, O.A, Wyatt, K, David, L.L, Wistow, G.J, Slingsby, C. | | Deposit date: | 2007-06-07 | | Release date: | 2007-06-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Evolutionary Adaptation of Human and Mouse Eye Lens Gammac-Crystallins for Solubility and Stability: Fine-Tuning of Molecular Dipoles.
J.Mol.Biol., 372, 2007
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3QP1
 | | Crystal structure of CviR ligand-binding domain bound to the native ligand C6-HSL | | Descriptor: | CviR transcriptional regulator, N-[(3S)-2-oxotetrahydrofuran-3-yl]hexanamide | | Authors: | Chen, G, Swem, L, Swem, D, Stauff, D, O'Loughlin, C, Jeffrey, P, Bassler, B, Hughson, F. | | Deposit date: | 2011-02-11 | | Release date: | 2011-03-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | A strategy for antagonizing quorum sensing.
Mol.Cell, 42, 2011
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2Y22
 | | Human AlphaB-crystallin Domain (residues 67-157) | | Descriptor: | ALPHA-CRYSTALLIN B | | Authors: | Naylor, C.E, Bagneris, C, Clark, A.R, Keep, N.H, Slingsby, C. | | Deposit date: | 2010-12-13 | | Release date: | 2011-03-02 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove
J.Mol.Biol., 408, 2011
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2Y1Y
 | | Human alphaB crystallin ACD(residues 71-157) | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, ALPHA-CRYSTALLIN B CHAIN, | | Authors: | Naylor, C.E, Bagneris, C, Clark, A.R, Keep, N.H, Slingsby, C. | | Deposit date: | 2010-12-10 | | Release date: | 2011-03-02 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove
J.Mol.Biol., 408, 2011
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2AUB
 | | Lysozyme structure derived from thin-film-based crystals | | Descriptor: | Lysozyme C | | Authors: | Pechkova, E, Sivozhelezov, V, Tropiano, G, Fiordoro, S, Nicolini, C. | | Deposit date: | 2005-08-27 | | Release date: | 2005-12-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Comparison of lysozyme structures derived from thin-film-based and classical crystals.
Acta Crystallogr.,Sect.D, 61, 2005
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1HXH
 | | COMAMONAS TESTOSTERONI 3BETA/17BETA HYDROXYSTEROID DEHYDROGENASE | | Descriptor: | 3BETA/17BETA-HYDROXYSTEROID DEHYDROGENASE | | Authors: | Benach, J, Filling, C, Oppermann, U.C.T, Roversi, P, Bricogne, G, Berndt, K.D, Jornvall, H, Ladenstein, R. | | Deposit date: | 2001-01-15 | | Release date: | 2002-12-25 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | Structure of Bacterial 3beta/17beta-Hydroxysteroid Dehydrogenase at 1.2 A Resolution: A Model for
Multiple Steroid Recognition
Biochemistry, 41, 2002
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2A54
 | | fluorescent protein asFP595, A143S, on-state, 1min irradiation | | Descriptor: | CHLORIDE ION, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | | Deposit date: | 2005-06-30 | | Release date: | 2005-08-16 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1BD7
 | | CIRCULARLY PERMUTED BB2-CRYSTALLIN | | Descriptor: | CIRCULARLY PERMUTED BB2-CRYSTALLIN | | Authors: | Wright, G, Basak, A.K, Mayr, E.-M, Glockshuber, R, Slingsby, C. | | Deposit date: | 1998-05-12 | | Release date: | 1998-10-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Circular permutation of betaB2-crystallin changes the hierarchy of domain assembly.
Protein Sci., 7, 1998
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3V0E
 | | Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 256-576(C363S) | | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | | Deposit date: | 2011-12-07 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | A glutamate switch controls voltage-sensitive phosphatase function.
Nat.Struct.Mol.Biol., 19, 2012
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3V0H
 | | Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), complexed with D-MYO-inositol-1,4,5-triphosphate | | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Voltage-sensor containing phosphatase | | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | | Deposit date: | 2011-12-08 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A glutamate switch controls voltage-sensitive phosphatase function.
Nat.Struct.Mol.Biol., 19, 2012
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3V0F
 | | Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP), residues 241-576(C363S), form II | | Descriptor: | PHOSPHATE ION, Voltage-sensor containing phosphatase | | Authors: | Liu, L, Kohout, S.C, Xu, Q, Muller, S, Kimberlin, C, Isacoff, E.Y, Minor, D.L. | | Deposit date: | 2011-12-07 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | A glutamate switch controls voltage-sensitive phosphatase function.
Nat.Struct.Mol.Biol., 19, 2012
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1GAM
 | | GAMMA B CRYSTALLIN TRUNCATED C-TERMINAL DOMAIN | | Descriptor: | GAMMA B CRYSTALLIN | | Authors: | Norledge, B.V, Mayr, E.-M, Glockshuber, R, Bateman, O.A, Slingsby, C, Jaenicke, R, Driessen, H.P.C. | | Deposit date: | 1996-02-02 | | Release date: | 1996-07-11 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The X-ray structures of two mutant crystallin domains shed light on the evolution of multi-domain proteins.
Nat.Struct.Biol., 3, 1996
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2A56
 | | fluorescent protein asFP595, A143S, on-state, 5min irradiation | | Descriptor: | GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | | Deposit date: | 2005-06-30 | | Release date: | 2005-08-16 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
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