1T9I
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![BU of 1t9i by Molmil](/molmil-images/mine/1t9i) | I-CreI(D20N)/DNA complex | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... | 著者 | Chevalier, B, Sussman, D, Otis, C, Boudreau, D, Turmel, M, Lemieux, C, Stephens, K, Monnat Jr, R.J, Stoddard, B.L. | 登録日 | 2004-05-17 | 公開日 | 2004-11-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Metal-Dependent DNA Cleavage Mechanism of the I-CreI LAGLIDADG Homing Endonuclease. Biochemistry, 43, 2004
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1T9J
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![BU of 1t9j by Molmil](/molmil-images/mine/1t9j) | I-CreI(Q47E)/DNA complex | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', DNA endonuclease I-CreI | 著者 | Chevalier, B, Sussman, D, Otis, C, Boudreau, D, Turmel, M, Lemieux, C, Stephens, K, Monnat Jr, R.J, Stoddard, B.L. | 登録日 | 2004-05-17 | 公開日 | 2004-11-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Metal-Dependent DNA Cleavage Mechanism of the I-CreI LAGLIDADG Homing Endonuclease. Biochemistry, 43, 2004
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1MOW
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![BU of 1mow by Molmil](/molmil-images/mine/1mow) | E-DreI | 分子名称: | 5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*G)-3', 5'-D(*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*GP*G)-3', GLYCEROL, ... | 著者 | Chevalier, B.S, Kortemme, T, Chadsey, M.S, Baker, D, Monnat Jr, R.J, Stoddard, B.L. | 登録日 | 2002-09-10 | 公開日 | 2002-11-29 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design, Activity and Structure of a Highly Specific Artificial Endonuclease Mol.Cell, 10, 2002
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1M5X
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![BU of 1m5x by Molmil](/molmil-images/mine/1m5x) | Crystal structure of the homing endonuclease I-MsoI bound to its DNA substrate | 分子名称: | 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... | 著者 | Chevalier, B, Turmel, M, Lemieux, C, Monnat, R.J, Stoddard, B.L. | 登録日 | 2002-07-10 | 公開日 | 2003-06-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI J.Mol.Biol., 329, 2003
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1N3E
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![BU of 1n3e by Molmil](/molmil-images/mine/1n3e) | Crystal structure of I-CreI bound to a palindromic DNA sequence I (palindrome of left side of wildtype DNA target sequence) | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3', 5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... | 著者 | Chevalier, B, Turmel, M, Lemieux, C, Monnat, R.J, Stoddard, B.L. | 登録日 | 2002-10-28 | 公開日 | 2003-06-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI J.Mol.Biol., 329, 2003
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1N3F
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![BU of 1n3f by Molmil](/molmil-images/mine/1n3f) | Crystal structure of I-CreI bound to a palindromic DNA sequence II (palindrome of right side of wildtype DNA target sequence) | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*GP*A)-3', 5'-D(P*GP*AP*CP*AP*GP*TP*TP*TP*CP*G-3'), CALCIUM ION, ... | 著者 | Chevalier, B, Turmel, M, Lemieux, C, Monnat, R.J, Stoddard, B.L. | 登録日 | 2002-10-28 | 公開日 | 2003-06-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI J.Mol.Biol., 329, 2003
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1G9Y
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![BU of 1g9y by Molmil](/molmil-images/mine/1g9y) | HOMING ENDONUCLEASE I-CREI / DNA SUBSTRATE COMPLEX WITH CALCIUM | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', CALCIUM ION, ... | 著者 | Chevalier, B, Monnat, R.J, Stoddard, B.L. | 登録日 | 2000-11-28 | 公開日 | 2001-04-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites. Nat.Struct.Biol., 8, 2001
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1G9Z
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![BU of 1g9z by Molmil](/molmil-images/mine/1g9z) | LAGLIDADG HOMING ENDONUCLEASE I-CREI / DNA PRODUCT COMPLEX WITH MAGNESIUM | 分子名称: | 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*A)-3', 5'-D(P*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', ... | 著者 | Chevalier, B, Monnat, R.J, Stoddard, B.L. | 登録日 | 2000-11-28 | 公開日 | 2001-04-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites. Nat.Struct.Biol., 8, 2001
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1QAV
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![BU of 1qav by Molmil](/molmil-images/mine/1qav) | Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of NNOS-Syntrophin Complex | 分子名称: | ALPHA-1 SYNTROPHIN (RESIDUES 77-171), NEURONAL NITRIC OXIDE SYNTHASE (RESIDUES 1-130) | 著者 | Hillier, B.J, Christopherson, K.S, Prehoda, K.E, Bredt, D.S, Lim, W.A. | 登録日 | 1999-03-30 | 公開日 | 1999-05-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science, 284, 1999
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1QAU
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![BU of 1qau by Molmil](/molmil-images/mine/1qau) | UNEXPECTED MODES OF PDZ DOMAIN SCAFFOLDING REVEALED BY STRUCTURE OF NNOS-SYNTROPHIN COMPLEX | 分子名称: | NEURONAL NITRIC OXIDE SYNTHASE (RESIDUES 1-130) | 著者 | Hillier, B.J, Christopherson, K.S, Prehoda, K.E, Bredt, D.S, Lim, W.A. | 登録日 | 1999-03-29 | 公開日 | 1999-05-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science, 284, 1999
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6XUC
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![BU of 6xuc by Molmil](/molmil-images/mine/6xuc) | Structure of coproheme decarboxylase from Corynebacterium diphteriae in complex with coproheme | 分子名称: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Chlorite dismutase | 著者 | Michlits, H, Lier, B, Pfanzagl, V, Djinovic-Carugo, K, Furtmueller, P.G, Oostenbrink, C, Obinger, C, Hofbauer, S. | 登録日 | 2020-01-17 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8702 Å) | 主引用文献 | Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation. Acs Catalysis, 10, 2020
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6XUB
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![BU of 6xub by Molmil](/molmil-images/mine/6xub) | Structure of coproheme decarboxylase from Corynebacterium diphteriae in complex with monovinyl monopropionyl deuteroheme | 分子名称: | Chlorite dismutase, harderoheme (III) | 著者 | Michlits, H, Lier, B, Pfanzagl, V, Djinovic-Carugo, K, Furtmueller, P.G, Oostenbrink, C, Obinger, C, Hofbauer, S. | 登録日 | 2020-01-17 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation. Acs Catalysis, 10, 2020
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1EVW
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![BU of 1evw by Molmil](/molmil-images/mine/1evw) | L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA. | 分子名称: | DNA (5'-D(*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*GP*GP*CP*TP*AP*CP*CP*TP*TP*AP*A)-3'), DNA (5'-D(P*GP*AP*GP*AP*GP*TP*CP*A)-3'), ... | 著者 | Galburt, E.A, Jurica, M.S, Chevalier, B.S, Erho, D, Stoddard, B.L. | 登録日 | 2000-04-20 | 公開日 | 2000-08-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site. J.Mol.Biol., 300, 2000
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1EVX
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![BU of 1evx by Molmil](/molmil-images/mine/1evx) | APO CRYSTAL STRUCTURE OF THE HOMING ENDONUCLEASE, I-PPOI | 分子名称: | INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, SULFATE ION, ZINC ION | 著者 | Galburt, E.A, Jurica, M.S, Chevalier, B.S, Erho, D, Stoddard, B.L. | 登録日 | 2000-04-20 | 公開日 | 2000-08-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site. J.Mol.Biol., 300, 2000
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6SHR
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![BU of 6shr by Molmil](/molmil-images/mine/6shr) | X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A | 分子名称: | Stromal cell-derived factor 1 | 著者 | Jugnarain, V.M, Mitchell, E, Forsyth, T, Michael, H, Cortes, S, Tillier, B. | 登録日 | 2019-08-08 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.745 Å) | 主引用文献 | X-RAY CRYSTAL STRUCTURE OF CELL-FREE PROTEIN SYNTHESIS (CFPS) PRODUCED SDF1-A To Be Published
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1CYQ
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![BU of 1cyq by Molmil](/molmil-images/mine/1cyq) | INTRON ENCODED HOMING ENDONUCLEASE I-PPOI (H98A)/DNA HOMING SITE COMPLEX | 分子名称: | 5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3', INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, MAGNESIUM ION, ... | 著者 | Galburt, E.A, Chevalier, B, Jurica, M.S, Flick, K.E, Stoddard, B.L. | 登録日 | 1999-08-31 | 公開日 | 1999-11-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | A novel endonuclease mechanism directly visualized for I-PpoI. Nat.Struct.Biol., 6, 1999
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1CZ0
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![BU of 1cz0 by Molmil](/molmil-images/mine/1cz0) | INTRON ENCODED HOMING ENDONUCLEASE I-PPOI/DNA COMPLEX LACKING CATALYTIC METAL ION | 分子名称: | DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON-ENCODED HOMING ENDONUCLEASE I-PPOI, SODIUM ION, ... | 著者 | Galburt, E.A, Chevalier, B, Jurica, M.S, Flick, K.E, Stoddard, B.L. | 登録日 | 1999-08-31 | 公開日 | 1999-11-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A novel endonuclease mechanism directly visualized for I-PpoI. Nat.Struct.Biol., 6, 1999
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4MLL
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![BU of 4mll by Molmil](/molmil-images/mine/4mll) | The 1.4 A structure of the class D beta-lactamase OXA-1 K70D complexed with oxacillin | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase OXA-1, ... | 著者 | June, C.M, Vallier, B.C, Bonomo, R.A, Leonard, D.A, Powers, R.A. | 登録日 | 2013-09-06 | 公開日 | 2013-10-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Structural Origins of Oxacillinase Specificity in Class D beta-Lactamases. Antimicrob.Agents Chemother., 58, 2014
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2MG6
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![BU of 2mg6 by Molmil](/molmil-images/mine/2mg6) | Non-reducible analogues of alpha-conotoxin Vc1.1: [3,16]-trans dicarba Vc1.1 | 分子名称: | Alpha-conotoxin Vc1A | 著者 | Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S. | 登録日 | 2013-10-28 | 公開日 | 2013-12-18 | 実験手法 | SOLUTION NMR | 主引用文献 | Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. Acs Chem.Biol., 8, 2013
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2MFX
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![BU of 2mfx by Molmil](/molmil-images/mine/2mfx) | Non-reducible analogues of alpha-conotoxin Vc1.1: [2,8]-cis dicarba Vc1.1 | 分子名称: | Alpha-conotoxin Vc1A | 著者 | Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S. | 登録日 | 2013-10-24 | 公開日 | 2013-12-18 | 実験手法 | SOLUTION NMR | 主引用文献 | Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. Acs Chem.Biol., 8, 2013
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2MFY
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![BU of 2mfy by Molmil](/molmil-images/mine/2mfy) | Non-reducible analogues of alpha-conotoxin Vc1.1: [2,8]-trans dicarba Vc1.1 | 分子名称: | Alpha-conotoxin Vc1A | 著者 | Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S. | 登録日 | 2013-10-24 | 公開日 | 2013-12-18 | 実験手法 | SOLUTION NMR | 主引用文献 | Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. Acs Chem.Biol., 8, 2013
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4F94
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![BU of 4f94 by Molmil](/molmil-images/mine/4f94) | Structure of the Class D Beta-Lactamase OXA-24 K84D in Acyl-Enzyme Complex with Oxacillin | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Beta-lactamase, SULFATE ION | 著者 | June, C.M, Vallier, B.C, Bonomo, R.A, Leonard, D.A, Powers, R.A. | 登録日 | 2012-05-18 | 公開日 | 2013-08-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Class D Beta-Lactamase OXA-24 K84D in Acyl-Enzyme Complex with Oxacillin To be Published
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