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PDB: 4 件

8DLF
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BU of 8dlf by Molmil
EBNA1 DNA binding domain (DBD) (458-617)+2 repeats of family repeat (FR) region
分子名称: 2XFR DNA (56-MER), Epstein-Barr nuclear antigen 1
著者Mei, Y, Lieberman, P.M, Murakami, K.
登録日2022-07-07
公開日2023-05-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Cryo-EM Structure and Functional Studies of EBNA1 Binding to the Family of Repeats and Dyad Symmetry Elements of Epstein-Barr Virus oriP.
J.Virol., 96, 2022
6VH6
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Crystal structure of Epstein-Barr Virus Nuclear Antigen-1, EBNA1, bound to fragment
分子名称: 4-hydroxy-6-methyl-2H-1-benzopyran-2-one, Epstein-Barr nuclear antigen 1
著者Messick, T.E, Lieberman, P.M.
登録日2020-01-09
公開日2020-05-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA.
Molecules, 25, 2020
6PW2
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Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication
分子名称: DNA (62-MER), DNA (62-MER) complementary DNA strand, Epstein-Barr nuclear antigen 1
著者Messick, T.E, Malecka, K.A, Lieberman, P.M.
登録日2019-07-22
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication.
J.Virol., 93, 2019
5T7X
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BU of 5t7x by Molmil
Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA
分子名称: DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1
著者Malecka, K.A, Messick, T.E, Lieberman, P.M.
登録日2016-09-06
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Oncotarget, 8, 2017

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件を2024-07-31に公開中

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