1QMP
| Phosphorylated aspartate in the crystal structure of the sporulation response regulator, Spo0A | Descriptor: | CALCIUM ION, Stage 0 sporulation protein A | Authors: | Lewis, R.J, Brannigan, J.A, Muchova, K, Barak, I, Wilkinson, A.J. | Deposit date: | 1999-10-04 | Release date: | 1999-11-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylated aspartate in the structure of a response regulator protein. J. Mol. Biol., 294, 1999
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6GQA
| Cell division regulator S. pneumoniae GpsB | Descriptor: | Cell cycle protein GpsB | Authors: | Lewis, R.J, Rutter, Z.J. | Deposit date: | 2018-06-07 | Release date: | 2019-01-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes. Nat Commun, 10, 2019
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6GQN
| Cell division regulator, S. pneumoniae GpsB, in complex with peptide fragment of Penicillin Binding Protein PBP2a | Descriptor: | Cell cycle protein GpsB, NICKEL (II) ION, SULFATE ION, ... | Authors: | Lewis, R.J, Rutter, Z.J. | Deposit date: | 2018-06-07 | Release date: | 2019-01-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes. Nat Commun, 10, 2019
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1FC3
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1B0N
| SINR PROTEIN/SINI PROTEIN COMPLEX | Descriptor: | PROTEIN (SINI PROTEIN), PROTEIN (SINR PROTEIN), ZINC ION | Authors: | Lewis, R.J, Brannigan, J.A, Offen, W.A, Smith, I, Wilkinson, A.J. | Deposit date: | 1998-11-11 | Release date: | 1999-01-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex. J.Mol.Biol., 283, 1998
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1DZ3
| DOMAIN-SWAPPING IN THE SPORULATION RESPONSE REGULATOR SPO0A | Descriptor: | SULFATE ION, Stage 0 sporulation protein A | Authors: | Lewis, R.J, Brannigan, J.A, Muchova, K, Leonard, G, Barak, I, Wilkinson, A.J. | Deposit date: | 2000-02-15 | Release date: | 2000-04-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Domain swapping in the sporulation response regulator Spo0A. J. Mol. Biol., 297, 2000
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5OMT
| Endonuclease NucB | Descriptor: | NucB | Authors: | Basle, A, Lewis, R.J. | Deposit date: | 2017-08-01 | Release date: | 2017-11-15 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of NucB, a biofilm-degrading endonuclease. Nucleic Acids Res., 46, 2018
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4UXV
| Cytoplasmic domain of bacterial cell division protein EzrA | Descriptor: | SEPTATION RING FORMATION REGULATOR EZRA | Authors: | Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J. | Deposit date: | 2014-08-27 | Release date: | 2014-10-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.961 Å) | Cite: | Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis. Nat.Commun., 5, 2014
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7TXF
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6TIF
| ReoM- Listeria monocytogenes | Descriptor: | SULFATE ION, UPF0297 protein lmo1503 | Authors: | Rutter, Z.J, Lewis, R.J. | Deposit date: | 2019-11-22 | Release date: | 2020-06-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | PrkA controls peptidoglycan biosynthesis through the essential phosphorylation of ReoM. Elife, 9, 2020
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3ZXJ
| Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, HIAXHD3, ... | Authors: | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-08-11 | Release date: | 2012-04-18 | Last modified: | 2012-05-02 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains. Proc.Natl.Acad.Sci.USA, 109, 2012
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3ZXK
| Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIAXHD3, alpha-L-arabinofuranose-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-08-11 | Release date: | 2012-04-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains. Proc.Natl.Acad.Sci.USA, 109, 2012
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3ZQ4
| Unusual, dual endo- and exo-nuclease activity in the degradosome explained by crystal structure analysis of RNase J1 | Descriptor: | CALCIUM ION, RIBONUCLEASE J 1, ZINC ION | Authors: | Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A, Harwood, C.R, Lewis, R.J. | Deposit date: | 2011-06-07 | Release date: | 2011-09-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Unusual, Dual Endo- and Exonuclease Activity in the Degradosome Explained by Crystal Structure Analysis of Rnase J1. Structure, 19, 2011
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3ZXN
| Moorella thermoacetica RsbS S58E | Descriptor: | ANTI-SIGMA-FACTOR ANTAGONIST (STAS) DOMAIN PROTEIN, THIOCYANATE ION | Authors: | Quin, M.B, Berrisford, J.M, Newman, J.A, Basle, A, Lewis, R.J, Marles-Wright, J. | Deposit date: | 2011-08-12 | Release date: | 2012-02-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Bacterial Stressosome: A Modular System that Has Been Adapted to Control Secondary Messenger Signaling. Structure, 20, 2012
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3ZXL
| Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HIAXHD3 | Authors: | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-08-11 | Release date: | 2012-04-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.871 Å) | Cite: | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains. Proc.Natl.Acad.Sci.USA, 109, 2012
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1H4Z
| Structure of the Anti-Sigma Factor Antagonist SpoIIAA in its Unphosphorylated Form | Descriptor: | ANTI-SIGMA F FACTOR ANTAGONIST | Authors: | Seavers, P.R, Lewis, R.J, Brannigan, J.A, Verschueren, K.H.G, Murshudov, G.N, Wilkinson, A.J. | Deposit date: | 2001-05-16 | Release date: | 2001-07-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Structure of the Bacillus Cell Fate Determinant Spoiiaa in Phosphorylated and Unphosphorylated Forms Structure, 9, 2001
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1H4X
| Structure of the Bacillus Cell Fate Determinant SpoIIAA in the Phosphorylated Form | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ANTI-SIGMA F FACTOR ANTAGONIST | Authors: | Seavers, P.R, Lewis, R.J, Brannigan, J.A, Verschueren, K.H.G, Murshudov, G.N, Wilkinson, A.J. | Deposit date: | 2001-05-15 | Release date: | 2001-07-06 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Structure of the Bacillus Cell Fate Determinant Spoiiaa in Phosphorylated and Unphosphorylated Forms Structure, 9, 2001
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7BN9
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4UY3
| Cytoplasmic domain of bacterial cell division protein ezra | Descriptor: | SEPTATION RING FORMATION REGULATOR EZRA | Authors: | Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J. | Deposit date: | 2014-08-28 | Release date: | 2014-10-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis. Nat.Commun., 5, 2014
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6GP7
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6GPZ
| Cell division regulator GpsB in complex with peptide fragment of L. monocytogenes Penicillin Binding Protein PBPA1 | Descriptor: | Cell cycle protein GpsB, IMIDAZOLE, LmPBPA1, ... | Authors: | Cleverley, R.M, Lewis, R.J, Rutter, Z.J. | Deposit date: | 2018-06-07 | Release date: | 2019-01-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes. Nat Commun, 10, 2019
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3K92
| Crystal structure of a E93K mutant of the majour Bacillus subtilis glutamate dehydrogenase RocG | Descriptor: | DI(HYDROXYETHYL)ETHER, NAD-specific glutamate dehydrogenase | Authors: | Gunka, K, Newman, J.A, Commichau, F.M, Herzberg, C, Rodrigues, C, Hewitt, L, Lewis, R.J, Stulke, J. | Deposit date: | 2009-10-15 | Release date: | 2010-06-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties J.Mol.Biol., 400, 2010
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3K8Z
| Crystal Structure of Gudb1 a decryptified secondary glutamate dehydrogenase from B. subtilis | Descriptor: | NAD-specific glutamate dehydrogenase | Authors: | Gunka, K, Newman, J.A, Commichau, F.M, Herzberg, C, Rodrigues, C, Hewitt, L, Lewis, R.J, Stulke, J. | Deposit date: | 2009-10-15 | Release date: | 2010-06-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties J.Mol.Biol., 400, 2010
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2VY9
| Molecular architecture of the stressosome, a signal integration and transduction hub | Descriptor: | ANTI-SIGMA-FACTOR ANTAGONIST | Authors: | Marles-Wright, J, Grant, T, Delumeau, O, van Duinen, G, Firbank, S.J, Lewis, P.J, Murray, J.W, Newman, J.A, Quin, M.B, Race, P.R, Rohou, A, Tichelaar, W, van Heel, M, Lewis, R.J. | Deposit date: | 2008-07-21 | Release date: | 2008-10-14 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub Science, 322, 2008
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4UG1
| GpsB N-terminal domain | Descriptor: | CELL CYCLE PROTEIN GPSB, IMIDAZOLE, NICKEL (II) ION | Authors: | Rismondo, J, Cleverley, R.M, Lane, H.V, Grohennig, S, Steglich, A, Muller, L, Krishna Mannala, G, Hain, T, Lewis, R.J, Halbedel, S. | Deposit date: | 2015-03-20 | Release date: | 2015-11-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the Bacterial Cell Division Determinant Gpsb and its Interaction with Penicillin Binding Proteins. Mol.Microbiol., 99, 2016
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