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PDB: 349 件

7D59
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cryo-EM structure of human RNA polymerase III in apo state
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M.
登録日2020-09-25
公開日2021-02-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
7D58
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cryo-EM structure of human RNA polymerase III in elongating state
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M.
登録日2020-09-25
公開日2021-02-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
7LH9
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Crystal structure of BRPF2 PWWP domain in complex with DNA
分子名称: Bromodomain-containing protein 1, DNA
著者Zhang, M, Lei, M, Qin, S, Dong, A, Yang, A, Li, Y, Loppnau, P, Hughes, T.R, Arrowsmith, C.H, Edwards, A.M, Min, J, Liu, J, Structural Genomics Consortium (SGC)
登録日2021-01-21
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains.
Biochim Biophys Acta Gene Regul Mech, 1864, 2021
6LI3
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cryo-EM structure of GPR52-miniGs-NB35
分子名称: G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Li, M, Wang, N, Xu, F, Wu, J, Lei, M.
登録日2019-12-10
公開日2020-02-26
最終更新日2020-03-18
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structural basis of ligand recognition and self-activation of orphan GPR52.
Nature, 579, 2020
7E34
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Crystal structure of SUN1-Speedy A-CDK2
分子名称: Cyclin-dependent kinase 2, GLYCEROL, SUN domain-containing protein 1, ...
著者Chen, Y, Huang, C, Wu, J, Lei, M.
登録日2021-02-08
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Nat Commun, 12, 2021
7D60
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Cryo-EM Structure of human CALHM5 in the presence of rubidium red
分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
著者Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
登録日2020-09-28
公開日2020-12-23
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
6K0A
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cryo-EM structure of an archaeal Ribonuclease P
分子名称: 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ...
著者Wan, F, Lan, P, Wu, J, Lei, M.
登録日2019-05-05
公開日2019-06-19
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
7D65
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Cryo-EM Structure of human CALHM5 in the presence of Ca2+
分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
著者Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
登録日2020-09-29
公開日2020-12-23
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7D61
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Cryo-EM Structure of human CALHM5 in the presence of EDTA
分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
著者Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
登録日2020-09-28
公開日2020-12-23
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7CUJ
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Crystal structure of fission yeast Ccq1 and Tpz1
分子名称: Coiled-coil quantitatively-enriched protein 1, Protection of telomeres protein tpz1
著者Sun, H, Wu, Z, Wu, J, Lei, M.
登録日2020-08-23
公開日2021-08-25
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex.
Plos Genet., 18, 2022
7CUH
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Crystal structure of fission yeast Pot1 and ssDNA
分子名称: Protection of telomeres protein 1, Telomere single-strand DNA
著者Sun, H, Wu, Z, Wu, J, Lei, M.
登録日2020-08-23
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex.
Plos Genet., 18, 2022
7CUI
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Crystal structure of fission yeast Pot1 and Tpz1
分子名称: Protection of telomeres protein 1, Protection of telomeres protein tpz1, SULFATE ION
著者Sun, H, Wu, Z, Wu, J, Lei, M.
登録日2020-08-23
公開日2021-08-25
最終更新日2022-09-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into Pot1-ssDNA, Pot1-Tpz1 and Tpz1-Ccq1 Interactions within fission yeast shelterin complex.
Plos Genet., 18, 2022
6K0B
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BU of 6k0b by Molmil
cryo-EM structure of archaeal Ribonuclease P with mature tRNA
分子名称: 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ...
著者Wan, F, Lan, P, Wu, J, Lei, M.
登録日2019-05-05
公開日2019-06-19
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
7BU5
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Crystal Structure of Human SLX4 and MUS81
分子名称: GLYCINE, MUS81 endonuclease homolog (Yeast), isoform CRA_b, ...
著者Wan, B, Wu, J, Lei, M.
登録日2020-04-04
公開日2021-04-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献SLX4 control MUS81 endonuclease function in telomere through an intermolecular SAP domain
To be published
6J0W
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Crystal Structure of Yeast Rtt107 and Nse6
分子名称: Peptide from DNA repair protein KRE29, Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
6J07
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Crystal structure of human TERB2 and TERB1
分子名称: Telomere repeats-binding bouquet formation protein 1, Telomere repeats-binding bouquet formation protein 2, ZINC ION
著者Wang, Y, Chen, Y, Wu, J, Huang, C, Lei, M.
登録日2018-12-21
公開日2019-02-27
実験手法X-RAY DIFFRACTION (3.298 Å)
主引用文献The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
6J0V
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Crystal Structure of Yeast Rtt107
分子名称: Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.314 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
6J0Y
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Crystal Structure of Yeast Rtt107 and Slx4
分子名称: Peptide from Structure-specific endonuclease subunit SLX4, Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
6J67
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Crystal structure of the compound 34 in a complex with TRF2
分子名称: 3FB-PHE-B8R-LEU-5XU-PRO, Telomeric repeat-binding factor 2
著者Chen, Y, Yang, Y, Lei, M.
登録日2019-01-14
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction.
ACS Med Chem Lett, 9, 2018
6J0X
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Crystal Structure of Yeast Rtt107 and Mms22
分子名称: Peptide from E3 ubiquitin-protein ligase substrate receptor MMS22, Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
6J08
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Crystal structure of human MAJIN and TERB2
分子名称: Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2
著者Wang, Y, Chen, Y, Wu, J, Huang, C, Lei, M.
登録日2018-12-21
公開日2019-02-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
6L7O
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cryo-EM structure of cyanobacteria Fd-NDH-1L complex
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ...
著者Zhang, C, Shuai, J, Wu, J, Lei, M.
登録日2019-11-02
公開日2020-02-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into NDH-1 mediated cyclic electron transfer.
Nat Commun, 11, 2020
6LBS
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Crystal structure of yeast Stn1
分子名称: KLLA0C11825p
著者Ge, Y, Wu, Z, Wu, J, Lei, M.
登録日2019-11-14
公開日2020-07-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into telomere protection and homeostasis regulation by yeast CST complex.
Nat.Struct.Mol.Biol., 27, 2020
6LBR
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Crystal structure of yeast Cdc13 and ssDNA
分子名称: KLLA0F20922p, Telomere single-strand DNA
著者Ge, Y, Wu, Z, Wu, J, Lei, M.
登録日2019-11-14
公開日2020-07-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into telomere protection and homeostasis regulation by yeast CST complex.
Nat.Struct.Mol.Biol., 27, 2020
6LBT
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Crystal structure of yeast Cdc13 and Stn1
分子名称: GLYCEROL, KLLA0C11825p, KLLA0F20922p,KLLA0F20922p
著者Ge, Y, Wu, Z, Wu, J, Lei, M.
登録日2019-11-14
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into telomere protection and homeostasis regulation by yeast CST complex.
Nat.Struct.Mol.Biol., 27, 2020

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