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PDB: 96 件

7FUP
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Crystal Structure of human cyclic GMP-AMP synthase in complex with methyl 1-benzoyl-3-methyl-5-(1,2-oxazol-5-yl)pyrazole-4-carboxylate
分子名称: Cyclic GMP-AMP synthase, PROPANOIC ACID, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
7FU1
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BU of 7fu1 by Molmil
Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-[3-[[(5-bromo-2-hydroxybenzoyl)amino]methyl]phenyl]-2-methylpyrazole-3-carboxylic acid
分子名称: (3P)-3-{3-[(5-bromo-2-hydroxybenzamido)methyl]phenyl}-1-methyl-1H-pyrazole-5-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION
著者Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G.
登録日2023-02-08
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献Crystal Structure of a human cyclic GMP-AMP synthase complex
To be published
4Y8W
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BU of 4y8w by Molmil
Crystal Structure of Human Cytochrome P450 21A2 Progesterone Complex
分子名称: Cytochrome P450 21-hydroxylase, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Pallan, P.S, Lei, L, Egli, M.
登録日2015-02-16
公開日2015-04-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYMEPROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE.
J.Biol.Chem., 290, 2015
1SE6
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BU of 1se6 by Molmil
Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SPERMINE (FULLY PROTONATED FORM), ...
著者Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R.
登録日2004-02-16
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2.
J.Biol.Chem., 280, 2005
1S1F
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BU of 1s1f by Molmil
Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways
分子名称: 4-PHENYL-1H-IMIDAZOLE, GLYCEROL, MALONIC ACID, ...
著者Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R.
登録日2004-01-06
公開日2005-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2
J.Biol.Chem., 280, 2005
3MN0
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BU of 3mn0 by Molmil
Introducing a 2-His-1-Glu Non-Heme Iron Center into Myoglobin confers Nitric Oxide Reductase activity: Cu(II)-CN-FeBMb(-His) form
分子名称: COPPER (II) ION, CYANIDE ION, Myoglobin, ...
著者Lin, Y.-W, Yeung, N, Gao, Y.-G, Miner, K.D, Lei, L, Robinson, H, Lu, Y.
登録日2010-04-20
公開日2010-08-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Introducing a 2-his-1-glu nonheme iron center into myoglobin confers nitric oxide reductase activity.
J.Am.Chem.Soc., 132, 2010
3K9Z
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Rational Design of a Structural and Functional Nitric Oxide Reductase
分子名称: FE (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Yeung, N, Lin, Y.-W, Gao, Y.-G, Zhao, X, Russell, B.S, Lei, L, Miner, K.D, Robinson, H, Lu, Y.
登録日2009-10-16
公開日2009-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Rational design of a structural and functional nitric oxide reductase.
Nature, 462, 2009
5X3O
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BU of 5x3o by Molmil
Crystal structure of p-DiUb-S65-COOH
分子名称: D-ubiquitin, Polyubiquitin-B
著者Man, P, Shuai, G, Qian, Q, Lei, L.
登録日2017-02-06
公開日2017-04-12
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Structure of p-DiUb-S65-COOH at 2.19 Angstroms resolution.
To Be Published
5X3N
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BU of 5x3n by Molmil
Crystal structure of DiUb-K6
分子名称: PHOSPHATE ION, Polyubiquitin-B
著者Man, P, Shuai, G, Qian, Q, Lei, L.
登録日2017-02-06
公開日2017-04-12
実験手法X-RAY DIFFRACTION (1.649 Å)
主引用文献Structure of p-Ub-S65-NH2 at 1.82 Angstroms resolution.
To Be Published
5X3M
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crystal structure of p-Ub-S65-NH2
分子名称: D-ubiquitin, Polyubiquitin-B
著者Man, P, Shuai, G, Qian, Q, Lei, L.
登録日2017-02-06
公開日2017-04-05
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (1.818 Å)
主引用文献Structure of p-Ub-S65-NH2 at 1.82 Angstroms resolution
To Be Published
5XPK
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BU of 5xpk by Molmil
Crystal structure of ubiquitin-k6mimic
分子名称: D-ubiquitin, Ubiquitin
著者Man, P, Shuai, G, Qian, Q, Lei, L.
登録日2017-06-03
公開日2017-07-19
実験手法X-RAY DIFFRACTION (2.274 Å)
主引用文献Structure of ubiquitin-k6mimic at 2.27 Angstroms resolution.
To Be Published
5YV7
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BU of 5yv7 by Molmil
Racemic X-ray Structure of Calcicludine
分子名称: Kunitz-type serine protease inhibitor homolog calcicludine
著者Shuai, G, Qian, Q, Lei, L.
登録日2017-11-24
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.395 Å)
主引用文献Racemic X-ray Structure of Calcicludine
To Be Published
8GDA
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BU of 8gda by Molmil
Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein
分子名称: (2S,5R)-5-[(1E,3S)-4,4-difluoro-3-hydroxy-4-phenylbut-1-en-1-yl]-1-[6-(1H-tetrazol-5-yl)hexyl]pyrrolidin-2-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Shenming, H, Mengyao, X, Lei, L, Jiangqian, M, Sheng, C, Jinpeng, S.
登録日2023-03-03
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GDB
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Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein
分子名称: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Shenming, H, Mengyao, X, Lei, L, Jianqiang, M, Jinpeng, S.
登録日2023-03-03
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GDC
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BU of 8gdc by Molmil
Cryo-EM Structure of the Prostaglandin E2 Receptor 3 Coupled to G Protein
分子名称: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Shenming, H, Mengyao, X, Lei, L, Yang, D, Shiyi, G, Jinpeng, S.
登録日2023-03-03
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GD9
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BU of 8gd9 by Molmil
Cryo-EM Structure of the Prostaglandin E2 Receptor 4 Coupled to G Protein
分子名称: 4-({2-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]butyl}cyclopentyl]ethyl}sulfanyl)butanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Shenming, H, Mengyao, X, Lei, L, Yang, D, Sheng, C, Jinpeng, S.
登録日2023-03-03
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths.
Proc.Natl.Acad.Sci.USA, 120, 2023
3HDL
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BU of 3hdl by Molmil
Crystal Structure of Highly Glycosylated Peroxidase from Royal Palm Tree
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Watanabe, L, Moura, P.R, Bleicher, L, Nascimento, A.S, Zamorano, L.S, Calvete, J.J, Bursakov, S, Roig, M.G, Shnyrov, V.L, Polikarpov, I.
登録日2009-05-07
公開日2009-11-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia).
J.Struct.Biol., 169, 2010
3G9V
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BU of 3g9v by Molmil
Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
分子名称: Interleukin 22 receptor, alpha 2, Interleukin-22
著者de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I.
登録日2009-02-14
公開日2009-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.756 Å)
主引用文献Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
FEBS Lett., 583, 2009
3ILZ
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BU of 3ilz by Molmil
Structure of TR-alfa bound to selective thyromimetic GC-1 in P212121 space group
分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
著者Aparicio, R, Polikarpov, L, Bleicher, L.
登録日2009-08-07
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
2XJL
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BU of 2xjl by Molmil
Monomeric Human Cu,Zn Superoxide dismutase without Cu ligands
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, SODIUM ION, ...
著者Saraboji, K, Leinartaite, L, Nordlund, A, Oliveberg, M, Logan, D.T.
登録日2010-07-07
公開日2010-09-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the Als-Associated Enzyme Cu/Zn Superoxide Dismutase 1.
J.Am.Chem.Soc., 132, 2010
2XJK
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BU of 2xjk by Molmil
Monomeric Human Cu,Zn Superoxide dismutase
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Saraboji, K, Leinartaite, L, Nordlund, A, Oliveberg, M, Logan, D.T.
登録日2010-07-07
公開日2010-09-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Folding Catalysis by Transient Coordination of Zn2+ to the Cu Ligands of the Als-Associated Enzyme Cu/Zn Superoxide Dismutase 1.
J.Am.Chem.Soc., 132, 2010
3HZF
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BU of 3hzf by Molmil
Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group
分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
著者Aparicio, R, Bleicher, L, Polikarpov, I.
登録日2009-06-23
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
3HFF
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BU of 3hff by Molmil
Monomeric human Cu,Zn Superoxide dismutase without Zn ligands
分子名称: Superoxide dismutase [Cu-Zn], ZINC ION
著者Saraboji, K, Nordlund, A, Leinartait, L, Oliveberg, M, Logan, D.T.
登録日2009-05-11
公開日2009-06-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Functional features cause misfolding of the ALS-provoking enzyme SOD1.
Proc.Natl.Acad.Sci.USA, 106, 2009
2XZG
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Clathrin Terminal Domain Complexed with Pitstop 1
分子名称: 2-(4-AMINOBENZYL)-1,3-DIOXO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-5-SULFONATE, ACETATE ION, CLATHRIN HEAVY CHAIN 1, ...
著者Bulut, H, Von Kleist, L, Saenger, W, Haucke, V.
登録日2010-11-25
公開日2011-08-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition.
Cell(Cambridge,Mass.), 146, 2011
2X64
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GLUTATHIONE-S-TRANSFERASE FROM XYLELLA FASTIDIOSA
分子名称: CHLORIDE ION, GLUTATHIONE, GLUTATHIONE-S-TRANSFERASE
著者Muniz, J.R.C, Rodrigues, N.C, Bleicher, L, Travensolo, R.F, Garcia, W.
登録日2010-02-14
公開日2010-03-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biophysical Characterization of the Recombinant Glutathione-S-Transferase from Xylella
To be Published

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