6K64
| Application of anti-helix antibodies in protein structure determination (8188-3LRH) | 分子名称: | 3LRH intrabody, Protein A | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | 登録日 | 2019-06-01 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.933 Å) | 主引用文献 | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6K6A
| Application of anti-helix antibodies in protein structure determination (8188cys-3LRHcys) | 分子名称: | 3LRH intrabody, Engineered Protein A | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | 登録日 | 2019-06-02 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6K69
| Application of anti-helix antibodies in protein structure determination (9213-3LRH) | 分子名称: | 3LRH intrabody, Engineered T4 lysozyme | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | 登録日 | 2019-06-01 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6IYM
| |
8OM9
| MutSbeta bound to (CAG)2 DNA (open form) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... | 著者 | Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. | 登録日 | 2023-03-31 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | MutSbeta bound to (CAG)2 DNA (open form) To Be Published
|
|
8OLX
| MutSbeta bound to (CAG)2 DNA (canonical form) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein Msh2, ... | 著者 | Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. | 登録日 | 2023-03-30 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | MutSbeta bound to (CAG)2 DNA (canonical form) To Be Published
|
|
8OMO
| DNA-unbound MutSbeta-ATP complex (bent clamp form) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... | 著者 | Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. | 登録日 | 2023-03-31 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | DNA-unbound MutSbeta-ATP complex (bent clamp form) To Be Published
|
|
8OM5
| DNA-free open form of MutSbeta | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... | 著者 | Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. | 登録日 | 2023-03-31 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | DNA-free open form of MutSbeta To Be Published
|
|
8OMA
| MutSbeta bound to 61bp homoduplex DNA | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... | 著者 | Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. | 登録日 | 2023-03-31 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | MutSbeta bound to 61bp homoduplex DNA To Be Published
|
|
8OMQ
| DNA-unbound MutSbeta-ATP complex (straight clamp form) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ... | 著者 | Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C. | 登録日 | 2023-03-31 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | DNA-unbound MutSbeta-ATP complex (straight clamp form) To Be Published
|
|
5DO7
| Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8 | 分子名称: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8 | 著者 | Lee, J.-Y, Kinch, L.N, Borek, D.M, Urbatsch, I.L, Xie, X.-S, Grishin, N.V, Cohen, J.C, Otwinowski, Z, Hobbs, H.H, Rosenbaum, D.M. | 登録日 | 2015-09-10 | 公開日 | 2016-05-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.93 Å) | 主引用文献 | Crystal structure of the human sterol transporter ABCG5/ABCG8. Nature, 533, 2016
|
|
2AOR
| Crystal structure of MutH-hemimethylated DNA complex | 分子名称: | 5'-D(*CP*AP*GP*GP*(6MA)P*TP*CP*CP*AP*AP*GP*CP*TP*TP*GP*GP*AP*TP*CP*CP*TP*G)-3', CALCIUM ION, DNA mismatch repair protein mutH | 著者 | Lee, J.Y, Chang, J, Joseph, N, Ghirlando, R, Rao, D.N, Yang, W. | 登録日 | 2005-08-13 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol.Cell, 20, 2005
|
|
1NC3
| Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with formycin A (FMA) | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, MTA/SAH nucleosidase | 著者 | Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L. | 登録日 | 2002-12-04 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis. J.Biol.Chem., 278, 2003
|
|
7COE
| Crystal structure of Receptor binding domain of MERS-CoV and KNIH90-F1 Fab complex | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, ... | 著者 | Lee, J.Y, Song, J.Y, Lee, H.S, Hong, E, Jang, T.H. | 登録日 | 2020-08-04 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The structure of a novel antibody against the spike protein inhibits Middle East respiratory syndrome coronavirus infections. Sci Rep, 12, 2022
|
|
7CM0
| Crystal structure of a glutaminyl cyclase in complex with NHV-1009 | 分子名称: | 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea, Glutaminyl-peptide cyclotransferase, ZINC ION | 著者 | Lee, J.W, Song, J.Y, Jang, T.H, Ha, J.H. | 登録日 | 2020-07-23 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design. Eur.J.Med.Chem., 226, 2021
|
|
8T46
| |
3INU
| Crystal structure of an unbound KZ52 neutralizing anti-Ebolavirus antibody. | 分子名称: | GLYCEROL, KZ52 antibody fragment heavy chain, KZ52 antibody fragment light chain, ... | 著者 | Lee, J.E, Fusco, M.L, Abelson, D.M, Hessell, A.J, Burton, D.R, Saphire, E.O. | 登録日 | 2009-08-12 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein. Acta Crystallogr.,Sect.D, 65, 2009
|
|
6KTB
| Crystal structure of B. halodurans MntR in apo form | 分子名称: | HTH-type transcriptional regulator MntR, MAGNESIUM ION, MANGANESE (II) ION, ... | 著者 | Lee, J.Y, Lee, M.Y. | 登録日 | 2019-08-26 | 公開日 | 2019-12-04 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of the manganese transport regulator MntR from Bacillus halodurans in apo and manganese bound forms. Plos One, 14, 2019
|
|
8T4J
| |
8T4G
| |
8T4I
| |
8T4F
| |
8T4H
| |
8T4E
| |
5V8L
| BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody, ... | 著者 | Lee, J.H, Ward, A.B. | 登録日 | 2017-03-22 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure. Immunity, 46, 2017
|
|