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PDB: 8 件

2QDI
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Drosophila OBP LUSH D118A mutation
分子名称: General odorant-binding protein lush, TRIETHYLENE GLYCOL
著者Laughlin, J.D, Jones, D.N.M.
登録日2007-06-20
公開日2008-06-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein.
Cell(Cambridge,Mass.), 133, 2008
2GTE
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Drosophila OBP LUSH bound to attractant pheromone 11-cis-vaccenyl acetate
分子名称: (Z)-OCTADEC-11-ENYL ACETATE, General odorant-binding protein lush, PHOSPHATE ION
著者Laughlin, J.D, Ha, T, Smith, D.P, Jones, D.N.M.
登録日2006-04-27
公開日2007-06-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein
Cell(Cambridge,Mass.), 133, 2008
3KVX
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JNK3 bound to aminopyrimidine inhibitor, SR-3562
分子名称: Mitogen-activated protein kinase 10, N-[(2Z)-4-(3-fluoro-5-morpholin-4-ylphenyl)pyrimidin-2(1H)-ylidene]-4-(3-morpholin-4-yl-1H-1,2,4-triazol-1-yl)aniline
著者Habel, J.E, Laughlin, J.D, LoGrasso, P.
登録日2009-11-30
公開日2009-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Synthesis, Biological Evaluation, X-ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) Inhibitors
J.Med.Chem., 53, 2010
3V6R
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Discovery of potent and selective covalent inhibitors of JNK
分子名称: 4-{[4-(dimethylamino)butanoyl]amino}-N-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
著者Park, H, LoGrasso, P.V, Laughlin, J.D.
登録日2011-12-20
公開日2012-02-01
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
3V6S
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Discovery of potent and selective covalent inhibitors of JNK
分子名称: 3-{[4-(dimethylamino)butanoyl]amino}-N-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
著者Park, H, Laughlin, J.D, LoGrasso, P.V.
登録日2011-12-20
公開日2012-02-01
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
4H3B
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Crystal Structure of JNK3 in Complex with SAB Peptide
分子名称: Mitogen-activated protein kinase 10, SH3 domain-binding protein 5
著者Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V.
登録日2012-09-13
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases.
Structure, 20, 2012
4H36
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Crystal Structure of JNK3 in Complex with ATF2 Peptide
分子名称: Cyclic AMP-dependent transcription factor ATF-2, Mitogen-activated protein kinase 10
著者Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V.
登録日2012-09-13
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases.
Structure, 20, 2012
4H39
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Crystal Structure of JNK3 in Complex with JIP1 Peptide
分子名称: C-Jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 10
著者Nwachukwu, J.C, Laughlin, J.D, Figuera-Losada, M, Cherry, L, Nettles, K.W, LoGrasso, P.V.
登録日2012-09-13
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases.
Structure, 20, 2012

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件を2024-10-30に公開中

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