4X21
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x21 by Molmil](/molmil-images/mine/4x21) | The MAP kinase JNK3 as target for halogen bonding | Descriptor: | CHLORIDE ION, Mitogen-activated protein kinase 10, N-ethyl-4-{[4-(1H-indol-3-yl)-5-iodopyrimidin-2-yl]amino}piperidine-1-carboxamide | Authors: | Lange, A, Buettner, F.M, Guenther, M.B, Zimmermann, M.O, Hennig, S, Laufer, S.A, Stehle, T, Boeckler, F. | Deposit date: | 2014-11-25 | Release date: | 2015-11-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond. J.Am.Chem.Soc., 137, 2015
|
|
2L0T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l0t by Molmil](/molmil-images/mine/2l0t) | Solution structure of the complex of ubiquitin and the VHS domain of Stam2 | Descriptor: | Signal transducing adapter molecule 2, Ubiquitin | Authors: | Lange, A, Hoeller, D, Wienk, H, Marcillat, O, Lancelin, J, Walker, O. | Deposit date: | 2010-07-15 | Release date: | 2010-12-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin. Biochemistry, 50, 2011
|
|
1XSW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xsw by Molmil](/molmil-images/mine/1xsw) | The solid-state NMR structure of Kaliotoxin | Descriptor: | Kaliotoxin 1 | Authors: | Lange, A, Becker, S, Seidel, K, Giller, K, Pongs, O, Baldus, M. | Deposit date: | 2004-10-20 | Release date: | 2005-04-05 | Last modified: | 2022-03-02 | Method: | SOLID-STATE NMR | Cite: | A Concept for Rapid Protein-Structure Determination by Solid-State NMR Spectroscopy Angew.Chem.Int.Ed.Engl., 44, 2005
|
|
1C12
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1c12 by Molmil](/molmil-images/mine/1c12) | INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE | Descriptor: | PROTEIN (ANTIBODY FRAGMENT FAB), TRAZEOLIDE | Authors: | Langedijk, A.C, Spinelli, S, Anguille, C, Hermans, P, Nederlof, J, Butenandt, J, Honegger, A, Cambillau, C, Pluckthun, A. | Deposit date: | 1999-07-20 | Release date: | 1999-08-14 | Last modified: | 2018-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insight into odorant perception: the crystal structure and binding characteristics of antibody fragments directed against the musk odorant traseolide. J.Mol.Biol., 292, 1999
|
|
2KV7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kv7 by Molmil](/molmil-images/mine/2kv7) | NMR solution structure of a soluble PrgI mutant from Salmonella Typhimurium | Descriptor: | Protein prgI | Authors: | Schmidt, H, Poyraz, O, Seidel, K, Delissen, F, Ader, C, Tenenboim, H, Goosmann, C, Laube, B, Thuenemann, A.F, Zychlinski, A, Baldus, M, Lange, A, Griesinger, C, Kolbe, M. | Deposit date: | 2010-03-09 | Release date: | 2010-06-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Protein refolding is required for assembly of the type three secretion needle. Nat.Struct.Mol.Biol., 17, 2010
|
|
2LPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lpz by Molmil](/molmil-images/mine/2lpz) | Atomic model of the Type-III Secretion System Needle | Descriptor: | Protein prgI | Authors: | Loquet, A, Sgourakis, N.G, Gupta, R, Giller, K, Riedel, D, Goosmann, C, Griesinger, C, Kolbe, M.G, Baker, D, Becker, S, Lange, A. | Deposit date: | 2012-02-21 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Atomic model of the type III secretion system needle. Nature, 486, 2012
|
|
1C7Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1c7z by Molmil](/molmil-images/mine/1c7z) | REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | FRUCTOSE-2,6-BISPHOSPHATASE, GLYCERALDEHYDE-3-PHOSPHATE, PHOSPHATE ION | Authors: | Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J. | Deposit date: | 2000-04-03 | Release date: | 2003-06-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published
|
|
1C81
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1c81 by Molmil](/molmil-images/mine/1c81) | MICHAELIS COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | 2,5-anhydro-1-deoxy-1-phosphono-6-O-phosphono-D-glucitol, FRUCTOSE-2,6-BISPHOSPHATASE | Authors: | Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J. | Deposit date: | 2000-04-03 | Release date: | 2003-06-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published
|
|
1C80
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1c80 by Molmil](/molmil-images/mine/1c80) | REGULATORY COMPLEX OF FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | FRUCTOSE-2,6-BISPHOSPHATASE, GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION | Authors: | Lee, Y.H, Olson, T.W, McClard, R.W, Witte, J.F, McFarlan, S.C, Banaszak, L.J, Levitt, D.G, Lange, A.J. | Deposit date: | 2000-04-03 | Release date: | 2003-06-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Reaction Mechanism of Fructose-2,6-bisphosphatase Suggested by the Crystal Structures of a pseudo-Michaelis complex and Metabolite Complexes To be Published
|
|
2KJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kj3 by Molmil](/molmil-images/mine/2kj3) | High-resolution structure of the HET-s(218-289) prion in its amyloid form obtained by solid-state NMR | Descriptor: | Small s protein | Authors: | Van Melckebeke, H, Wasmer, C, Lange, A, AB, E, Loquet, A, Meier, B.H. | Deposit date: | 2009-05-20 | Release date: | 2010-06-02 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR | Cite: | Atomic-Resolution Three-Dimensional Structure of HET-s(218-289) Amyloid Fibrils by Solid-State NMR Spectroscopy J.Am.Chem.Soc., 132, 2010
|
|
6YEG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yeg by Molmil](/molmil-images/mine/6yeg) | Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - Final EM Refinement | Descriptor: | Tail tube protein gp17.1* | Authors: | Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A. | Deposit date: | 2020-03-24 | Release date: | 2020-10-14 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | Cite: | Architecture of the flexible tail tube of bacteriophage SPP1. Nat Commun, 11, 2020
|
|
6YQ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yq5 by Molmil](/molmil-images/mine/6yq5) | Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - NMR Ensemble | Descriptor: | Tail tube protein gp17.1* | Authors: | Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A. | Deposit date: | 2020-04-16 | Release date: | 2020-10-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | Cite: | Architecture of the flexible tail tube of bacteriophage SPP1. Nat Commun, 11, 2020
|
|
1TIP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tip by Molmil](/molmil-images/mine/1tip) | THE BISPHOSPHATASE DOMAIN OF THE BIFUNCTIONAL RAT LIVER 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, PHOSPHOENZYME INTERMEDIATE OF FRU-2,6-BISPHOSPHATASE | Authors: | Lee, Y.-H, Olson, T.W, Ogata, C.M, Levitt, D.G, Banaszak, L.J, Lange, A.J. | Deposit date: | 1997-05-28 | Release date: | 1998-01-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a trapped phosphoenzyme during a catalytic reaction. Nat.Struct.Biol., 4, 1997
|
|
2X9C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2x9c by Molmil](/molmil-images/mine/2x9c) | Crystal structure of a soluble PrgI mutant from Salmonella Typhimurium | Descriptor: | PROTEIN PRGI | Authors: | Poyraz, O, Schmidt, H, Seidel, K, Delissen, F, Ader, C, Tenenboim, H, Goosmann, C, Laube, B, Thuenemann, A.F, Zychlinsky, A, Baldus, M, Lange, A, Griesinger, C, Kolbe, M. | Deposit date: | 2010-03-15 | Release date: | 2010-06-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Protein Refolding is Required for Assembly of the Type Three Secretion Needle Nat.Struct.Mol.Biol., 17, 2010
|
|
1UN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1un0 by Molmil](/molmil-images/mine/1un0) | Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment | Descriptor: | IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2 | Authors: | Matsuura, Y, Lange, A, Harreman, M.T, Corbett, A.H, Stewart, M. | Deposit date: | 2003-09-03 | Release date: | 2003-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import Embo J., 22, 2003
|
|
2RNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rnm by Molmil](/molmil-images/mine/2rnm) | Structure of The HET-s(218-289) prion in its amyloid form obtained by solid-state NMR | Descriptor: | Small s protein | Authors: | Wasmer, C, Lange, A, Van Melckebeke, H, Siemer, A, Riek, R, Meier, B.H. | Deposit date: | 2008-01-24 | Release date: | 2008-04-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core Science, 319, 2008
|
|
2UVS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2uvs by Molmil](/molmil-images/mine/2uvs) | High Resolution Solid-state NMR structure of Kaliotoxin | Descriptor: | POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.1 | Authors: | Korukottu, J, Lange, A, Vijayan, V, Schneider, R, Pongs, O, Becker, S, Baldus, M, Zweckstetter, M. | Deposit date: | 2007-03-14 | Release date: | 2008-05-27 | Last modified: | 2020-01-15 | Method: | SOLID-STATE NMR | Cite: | Conformational Plasticity in Ion Channel Recognition of a Peptide Toxin To be Published
|
|
2MME
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mme by Molmil](/molmil-images/mine/2mme) | Hybrid structure of the Shigella flexneri MxiH Type three secretion system needle | Descriptor: | MxiH | Authors: | Demers, J.P, Habenstein, B, Loquet, A, Vasa, S.K, Becker, S, Baker, D, Lange, A, Sgourakis, N.G. | Deposit date: | 2014-03-14 | Release date: | 2014-10-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.7 Å), SOLID-STATE NMR | Cite: | High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy. Nat Commun, 5, 2014
|
|
2MEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mex by Molmil](/molmil-images/mine/2mex) | Structure of the tetrameric building block of the Salmonella Typhimurium PrgI Type three secretion system needle | Descriptor: | Protein PrgI | Authors: | Loquet, A, Habenstein, B, Chevelkov, V, Giller, K, Becker, S, Lange, A. | Deposit date: | 2013-10-01 | Release date: | 2013-12-25 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR | Cite: | Atomic structure and handedness of the building block of a biological assembly. J.Am.Chem.Soc., 135, 2013
|
|
2MSG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2msg by Molmil](/molmil-images/mine/2msg) | Solid-state NMR structure of ubiquitin | Descriptor: | Ubiquitin | Authors: | Lakomek, N, Habenstein, B, Loquet, A, Shi, C, Giller, K, Wolff, S, Becker, S, Fasshuber, H, Lange, A. | Deposit date: | 2014-08-04 | Release date: | 2015-02-18 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structural heterogeneity in microcrystalline ubiquitin studied by solid-state NMR. Protein Sci., 24, 2015
|
|
2N7H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n7h by Molmil](/molmil-images/mine/2n7h) | Hybrid structure of the Type 1 Pilus of Uropathogenic E.coli | Descriptor: | FimA | Authors: | Habenstein, B, Loquet, A, Giller, K, Vasa, S, Becker, S, Habeck, M, Lange, A. | Deposit date: | 2015-09-11 | Release date: | 2015-09-23 | Last modified: | 2015-10-14 | Method: | SOLID-STATE NMR | Cite: | Hybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coli. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
2N3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2n3d by Molmil](/molmil-images/mine/2n3d) | Atomic structure of the cytoskeletal bactofilin BacA revealed by solid-state NMR | Descriptor: | Bactofilin A | Authors: | Shi, C, Fricke, P, Lin, L, Chevelkov, V, Wegstroth, M, Giller, K, Becker, S, Thanbichler, M, Lange, A. | Deposit date: | 2015-05-29 | Release date: | 2015-12-16 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR. Sci Adv, 1, 2015
|
|
1JJ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jj9 by Molmil](/molmil-images/mine/1jj9) | Crystal Structure of MMP8-Barbiturate Complex Reveals Mechanism for Collagen Substrate Recognition | Descriptor: | 2-HYDROXY-5-[4-(2-HYDROXY-ETHYL)-PIPERIDIN-1-YL]-5-PHENYL-1H-PYRIMIDINE-4,6-DIONE, CALCIUM ION, Matrix Metalloproteinase 8, ... | Authors: | Brandstetter, H, Grams, F, Glitz, D, Lang, A, Huber, R, Bode, W, Krell, H.-W, Engh, R.A. | Deposit date: | 2001-07-04 | Release date: | 2001-08-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition. J.Biol.Chem., 276, 2001
|
|
4O9Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o9y by Molmil](/molmil-images/mine/4o9y) | Crystal Structure of TcdA1 | Descriptor: | TcdA1 | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | Deposit date: | 2014-01-03 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.502 Å) | Cite: | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
|
|
4O9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o9x by Molmil](/molmil-images/mine/4o9x) | Crystal Structure of TcdB2-TccC3 | Descriptor: | MERCURY (II) ION, TcdB2, TccC3 | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | Deposit date: | 2014-01-03 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
|
|