1OWJ
| Substituted 2-Naphthamidine Inhibitors of Urokinase | 分子名称: | 6-[(Z)-AMINO(IMINO)METHYL]-N-(1-ISOPROPYL-3,4-DIHYDROISOQUINOLIN-7-YL)-2-NAPHTHAMIDE, Urokinase-type plasminogen activator | 著者 | Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. | 登録日 | 2003-03-28 | 公開日 | 2003-09-30 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004
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1OWK
| Substituted 2-Naphthamidine Inhibitors of Urokinase | 分子名称: | 6-[(Z)-AMINO(IMINO)METHYL]-N-(1-ISOPROPYL-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)-2-NAPHTHAMIDE, Urokinase-type plasminogen activator | 著者 | Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. | 登録日 | 2003-03-28 | 公開日 | 2003-09-30 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004
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1OWI
| Substituted 2-Naphthamidine Inhibitors of Urokinase | 分子名称: | 6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE, Urokinase-type plasminogen activator | 著者 | Wendt, M.D, Rockway, T.W, Geyer, A, McClellan, W, Weitzberg, M, Zhao, X, Mantei, R, Nienaber, V.L, Stewart, K, Klinghofer, V, Giranda, V.L. | 登録日 | 2003-03-28 | 公開日 | 2003-09-30 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Identification of Novel Binding Interactions in the Development of Potent, Selective 2-Naphthamidine Inhibitors of Urokinase. Synthesis, Structural Analysis, and SAR of N-Phenyl Amide 6-Substitution. J.Med.Chem., 47, 2004
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2Q0J
| Structure of Pseudomonas Quinolone Signal Response Protein PqsE | 分子名称: | BENZOIC ACID, FE (III) ION, Quinolone signal response protein | 著者 | Yu, S, Jensen, V, Feldmann, I, Haussler, S, Blankenfeldt, W. | 登録日 | 2007-05-22 | 公開日 | 2008-06-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein. Biochemistry, 48, 2009
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3DSS
| Crystal structure of RabGGTase(DELTA LRR; DELTA IG) | 分子名称: | CALCIUM ION, Geranylgeranyl transferase type-2 subunit alpha, Geranylgeranyl transferase type-2 subunit beta, ... | 著者 | Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W. | 登録日 | 2008-07-14 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation Embo J., 27, 2008
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6EV1
| Crystal structure of antibody against schizophyllan | 分子名称: | Heavy chain, Light chain | 著者 | Sung, K.H, Josewski, J, Dubel, S, Blankenfeldt, W, Rau, U. | 登録日 | 2017-11-01 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.043 Å) | 主引用文献 | Structural insights into antigen recognition of an anti-beta-(1,6)-beta-(1,3)-D-glucan antibody. Sci Rep, 8, 2018
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6ET1
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6EYS
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6ET2
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6EYV
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6ET0
| Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | 著者 | Witzgall, F, Blankenfeldt, W. | 登録日 | 2017-10-25 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC. Chembiochem, 19, 2018
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6ESZ
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6EV2
| Crystal structure of antibody against schizophyllan in complex with laminarihexaose | 分子名称: | Heavy chain, Light chain, beta-D-glucopyranose, ... | 著者 | Sung, K.H, Josewski, J, Duebel, S, Blankenfeldt, W, Rau, U. | 登録日 | 2017-11-01 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Structural insights into antigen recognition of an anti-beta-(1,6)-beta-(1,3)-D-glucan antibody. Sci Rep, 8, 2018
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6ET3
| Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) | 分子名称: | (R,R)-2,3-BUTANEDIOL, PqsB, PqsC, ... | 著者 | Witzgall, F, Blankenfeldt, W. | 登録日 | 2017-10-25 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC. Chembiochem, 19, 2018
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3DST
| Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with geranylgeranyl pyrophosphate | 分子名称: | CALCIUM ION, GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl transferase type-2 subunit alpha, ... | 著者 | Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W. | 登録日 | 2008-07-14 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation Embo J., 27, 2008
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6FHP
| DAIP in complex with a C-terminal fragment of thermolysin | 分子名称: | Dispase autolysis-inducing protein, Thermolysin | 著者 | Schmelz, S, Fiebig, D, Fuchsbauer, H.L, Blankenfeldt, W, Scrima, A. | 登録日 | 2018-01-15 | 公開日 | 2018-09-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.703 Å) | 主引用文献 | Destructive twisting of neutral metalloproteases: the catalysis mechanism of the Dispase autolysis-inducing protein from Streptomyces mobaraensis DSM 40487. FEBS J., 285, 2018
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6FNT
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6FRH
| Crystal structure of Ssp DnaB Mini-Intein variant M86 | 分子名称: | Replicative DNA helicase,Replicative DNA helicase | 著者 | Popp, M.A, Blankenfeldt, W, Gazdag, M.E, Matern, J.J.C, Mootz, H.D. | 登録日 | 2018-02-15 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine. Chem Sci, 10, 2019
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3DSV
| Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with mono-prenylated peptide Ser-Cys-Ser-Cys(GG) derivated from Rab7 | 分子名称: | CALCIUM ION, GERAN-8-YL GERAN, Geranylgeranyl transferase type-2 subunit alpha, ... | 著者 | Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W. | 登録日 | 2008-07-14 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation Embo J., 27, 2008
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3DSU
| Crystal structure of RabGGTase(DELTA LRR; DELTA IG)in complex with farnesyl pyrophosphate | 分子名称: | CALCIUM ION, FARNESYL DIPHOSPHATE, Geranylgeranyl transferase type-2 subunit alpha, ... | 著者 | Guo, Z, Yu, S, Goody, R.S, Alexandrov, K, Blankenfeldt, W. | 登録日 | 2008-07-14 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation Embo J., 27, 2008
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6FNR
| Ergothioneine-biosynthetic methyltransferase EgtD in complex with chlorohistidine | 分子名称: | (2~{S})-2-chloranyl-3-(1~{H}-imidazol-5-yl)propanoic acid, GLYCEROL, Histidine N-alpha-methyltransferase, ... | 著者 | Vit, A, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2018-02-05 | 公開日 | 2018-06-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD. ACS Chem. Biol., 13, 2018
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6GKX
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6GKW
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6FRG
| Crystal structure of G-1F mutant of Ssp DnaB Mini-Intein variant M86 | 分子名称: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Replicative DNA helicase, ... | 著者 | Popp, M.A, Blankenfeldt, W, Friedel, K, Mootz, H.D. | 登録日 | 2018-02-15 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.535 Å) | 主引用文献 | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine. Chem Sci, 10, 2019
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3DH8
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