8BRU
| Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C | 分子名称: | CITRIC ACID, Methionine--tRNA ligase, ZINC ION | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | 登録日 | 2022-11-24 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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3CW6
| E. coli Initiator tRNA | 分子名称: | Initiator tRNA | 著者 | Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C. | 登録日 | 2008-04-21 | 公開日 | 2008-09-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis. Nucleic Acids Res., 36, 2008
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1XTY
| Crystal structure of Sulfolobus solfataricus peptidyl-tRNA hydrolase | 分子名称: | Peptidyl-tRNA hydrolase, SULFATE ION | 著者 | Fromant, M, Schmitt, E, Mechulam, Y, Lazennec, C, Plateau, P, Blanquet, S. | 登録日 | 2004-10-25 | 公開日 | 2005-03-22 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure at 1.8 A resolution and identification of active site residues of Sulfolobus solfataricus peptidyl-tRNA hydrolase. Biochemistry, 44, 2005
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2FMT
| METHIONYL-TRNAFMET FORMYLTRANSFERASE COMPLEXED WITH FORMYL-METHIONYL-TRNAFMET | 分子名称: | FORMYL-METHIONYL-TRNAFMET2, MAGNESIUM ION, METHIONYL-TRNA FMET FORMYLTRANSFERASE, ... | 著者 | Schmitt, E, Mechulam, Y, Blanquet, S. | 登録日 | 1998-07-29 | 公開日 | 1999-07-29 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet. EMBO J., 17, 1998
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7D5D
| Left-handed G-quadruplex containing one bulge | 分子名称: | 1xBulge-LHG4motif, POTASSIUM ION, SPERMINE | 著者 | Das, P, Ngo, K.H, Winnerdy, F.R, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2020-09-25 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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7D5E
| Left-handed G-quadruplex containing two bulges | 分子名称: | 2xBulge-LHG4motif, POTASSIUM ION, SODIUM ION, ... | 著者 | Das, P, Maity, A, Ngo, K.H, Winnerdy, F.R, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2020-09-25 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.296 Å) | 主引用文献 | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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7DFY
| Novel motif for left-handed G-quadruplex formation | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2xMotif2, POTASSIUM ION, ... | 著者 | Das, P, Winnerdy, F.R, Maity, A, Mechulam, Y, Phan, A.T. | 登録日 | 2020-11-10 | 公開日 | 2021-09-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | A novel minimal motif for left-handed G-quadruplex formation. Chem.Commun.(Camb.), 57, 2021
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7D5F
| Left-handed G-quadruplex containing 3 bulges | 分子名称: | 3xBulge-LHG4motif | 著者 | Winnerdy, F.R, Das, P, Ngo, K.H, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2020-09-25 | 公開日 | 2021-02-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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3H9C
| Structure of methionyl-tRNA synthetase: crystal form 2 | 分子名称: | CITRIC ACID, Methionyl-tRNA synthetase, ZINC ION | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | 登録日 | 2009-04-30 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. J.Mol.Biol., 394, 2009
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3FRH
| Structure of the 16S rRNA methylase RmtB, P21 | 分子名称: | 16S rRNA methylase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Schmitt, E, Galimand, M, Panvert, M, Dupechez, M, Courvalin, P, Mechulam, Y. | 登録日 | 2009-01-08 | 公開日 | 2009-08-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases J.Mol.Biol., 388, 2009
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1KJZ
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1KK2
| Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDP-Mg2+ | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | 著者 | Schmitt, E, Blanquet, S, Mechulam, Y. | 登録日 | 2001-12-06 | 公開日 | 2002-04-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J., 21, 2002
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1KK1
| Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDPNP-Mg2+ | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ZINC ION, ... | 著者 | Schmitt, E, Blanquet, S, Mechulam, Y. | 登録日 | 2001-12-06 | 公開日 | 2002-04-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J., 21, 2002
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1MKH
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3FRI
| Structure of the 16S rRNA methylase RmtB, I222 | 分子名称: | 16S rRNA methylase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Schmitt, E, Galimand, M, Panvert, M, Dupechez, M, Courvalin, P, Mechulam, Y. | 登録日 | 2009-01-08 | 公開日 | 2009-08-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases J.Mol.Biol., 388, 2009
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3FZG
| Structure of the 16S rRNA methylase ArmA | 分子名称: | 16S rRNA methylase, S-ADENOSYLMETHIONINE | 著者 | Schmitt, E, Galimand, M, Panvert, M, Courvalin, P, Mechulam, Y. | 登録日 | 2009-01-26 | 公開日 | 2009-08-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural bases for 16 S rRNA methylation catalyzed by ArmA and RmtB methyltransferases J.Mol.Biol., 388, 2009
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3H99
| Structure of a mutant methionyl-tRNA synthetase with modified specificity complexed with methionine | 分子名称: | CITRIC ACID, METHIONINE, Methionyl-tRNA synthetase, ... | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | 登録日 | 2009-04-30 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. J.Mol.Biol., 394, 2009
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3H97
| Structure of a mutant methionyl-tRNA synthetase with modified specificity | 分子名称: | CITRIC ACID, Methionyl-tRNA synthetase, ZINC ION | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | 登録日 | 2009-04-30 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. J.Mol.Biol., 394, 2009
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3H9B
| Structure of a mutant methionyl-tRNA synthetase with modified specificity complexed with azidonorleucine | 分子名称: | 6-azido-L-norleucine, CITRIC ACID, Methionyl-tRNA synthetase, ... | 著者 | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | 登録日 | 2009-04-30 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. J.Mol.Biol., 394, 2009
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3M4X
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2PTH
| PEPTIDYL-TRNA HYDROLASE FROM ESCHERICHIA COLI | 分子名称: | PEPTIDYL-TRNA HYDROLASE | 著者 | Schmitt, E, Mechulam, Y, Fromant, M, Plateau, P, Blanquet, S. | 登録日 | 1997-03-25 | 公開日 | 1998-03-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal structure at 1.2 A resolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase. EMBO J., 16, 1997
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2QMU
| Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, Translation initiation factor 2 alpha subunit, ... | 著者 | Yatime, L, Mechulam, Y, Blanquet, S, Schmitt, E. | 登録日 | 2007-07-17 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1FMT
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6GZ6
| Structure of a left-handed G-quadruplex | 分子名称: | DNA (27-MER), POTASSIUM ION | 著者 | Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T. | 登録日 | 2018-07-03 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | 主引用文献 | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew.Chem.Int.Ed.Engl., 58, 2019
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1JKE
| D-Tyr tRNATyr deacylase from Escherichia coli | 分子名称: | D-Tyr-tRNATyr deacylase, ZINC ION | 著者 | Ferri-Fioni, M.L, Schmitt, E, Soutourina, J, Plateau, P, Mechulam, Y, Blanquet, S. | 登録日 | 2001-07-12 | 公開日 | 2002-01-25 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases. J.Biol.Chem., 276, 2001
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