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PDB: 20 件
3NGH
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Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1
分子名称: PDZ domain-containing protein 1
著者Kocher, O, Birrane, G, Krieger, M, Ladias, J.A.
登録日2010-06-11
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1.
J.Biol.Chem., 285, 2010
1MFG
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The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
分子名称: Erb-B2 INTERACTING PROTEIN, Erb-B2 carboxyl-terminal fragment
著者Birrane, G, Chung, J, Ladias, J.A.
登録日2002-08-10
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
1MFL
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The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
分子名称: Erb-B2 INTERACTING PROTEIN, PHOSPHORYLATED Erb-B2 carboxyl-terminal fragment.
著者Birrane, G, Chung, J, Ladias, J.A.
登録日2002-08-12
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
3BYA
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Structure of a Calmodulin Complex
分子名称: CALCIUM ION, Calmodulin, Glutamate [NMDA] receptor subunit zeta-1 peptide
著者Birrane, G, Soni, A, Ladias, J.A.A.
登録日2008-01-15
公開日2009-01-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of a Calmodulin Complex
To be Published
2HO2
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Structure of human FE65-WW domain in complex with hMena peptide.
分子名称: Amyloid beta A4 protein-binding family B member 1, GLYCEROL, Protein enabled homolog
著者Meiyappan, M, Birrane, G, Ladias, J.A.
登録日2006-07-13
公開日2007-07-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
1GQ4
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STRUCTURAL DETERMINANTS OF THE NHERF INTERACTION WITH BETA2AR AND PDGFR
分子名称: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
著者Karthikeyan, S, Leung, T, Ladias, J.A.A.
登録日2001-11-19
公開日2002-05-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
1GQ5
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Structural Determinants of the NHERF Interaction with beta2-AR and PDGFR
分子名称: CHLORIDE ION, EZRIN-RADIXIN-MOESIN BINDING PHOSPHOPROTEIN-50
著者Karthikeyan, S, Leung, T, Ladias, J.A.A.
登録日2001-11-20
公開日2002-11-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Determinants of the Na+/H+ Exchanger Regulatory Factor Interaction with the Beta 2 Adrenergic and Platelet-Derived Growth Factor Receptors
J.Biol.Chem., 277, 2002
1QKL
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hRPABC14.4, essential subunit of human RNA polymerases I, II and III
分子名称: DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE
著者Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G.
登録日1999-07-26
公開日1999-11-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases
Nat.Struct.Biol., 6, 1999
1I92
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STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION
分子名称: CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR
著者Karthikeyan, S, Leung, T, Ladias, J.A.A.
登録日2001-03-16
公開日2001-06-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator.
J.Biol.Chem., 276, 2001
3CMY
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Structure of a homeodomain in complex with DNA
分子名称: 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ...
著者Birrane, G, Ladias, J.A.A, Soni, A.
登録日2008-03-24
公開日2009-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Basis for DNA Recognition by the Human PAX3 Homeodomain.
Biochemistry, 48, 2009
1G9O
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FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR
分子名称: NHE-RF
著者Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A.
登録日2000-11-26
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains.
J.Mol.Biol., 308, 2001
1Y98
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Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ...
著者Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A.
登録日2004-12-14
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005
4IGK
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Structure of human BRCA1 BRCT in complex with ATRIP peptide
分子名称: ATRIP peptide, Breast cancer type 1 susceptibility protein, GLYCEROL
著者Liu, X, Ladias, J.A.A.
登録日2012-12-17
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1.
Biochemistry, 52, 2013
4IFI
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Structure of human BRCA1 BRCT in complex with BAAT peptide
分子名称: ACETATE ION, BAAT peptide, Breast cancer type 1 susceptibility protein
著者Liu, X, Ladias, J.A.A.
登録日2012-12-14
公開日2013-10-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1.
Biochemistry, 52, 2013
2NTE
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Crystal Structure of the BARD1 BRCT Domains
分子名称: 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ...
著者Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A.
登録日2006-11-07
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
2OEI
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Crystal structure of human FE65-WW domain in complex with human Mena peptide
分子名称: Amyloid beta A4 protein-binding family B member 1, poly-proline peptide
著者Meiyappan, M, Birrane, G, Ladias, J.A.A.
登録日2006-12-29
公開日2007-07-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
2I53
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Crystal structure of Cyclin K
分子名称: ACETATE ION, Cyclin K
著者Baek, K, Brown, R.S, Birrane, G, Ladias, J.A.A.
登録日2006-08-23
公開日2007-01-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Human Cyclin K, a Positive Regulator of Cyclin-dependent Kinase 9.
J.Mol.Biol., 366, 2007
2IDH
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Crystal Structure of human FE65 WW domain
分子名称: Amyloid beta A4 protein-binding family B member 1, SULFATE ION, TETRAETHYLENE GLYCOL
著者Meiyappan, M, Birrane, G, Ladias, J.A.A.
登録日2006-09-15
公開日2007-07-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
2ING
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X-ray Structure of the BRCA1 BRCT mutant M1775K
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Birrane, G, Soni, A, Ladias, J.A.A.
登録日2006-10-07
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
2KG2
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Solution structure of a PDZ protein
分子名称: Tax1-binding protein 3
著者Durney, M.A, Birrane, G, Anklin, C, Soni, A, Ladias, J.A.A.
登録日2009-03-02
公開日2010-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the human Tax-interacting protein-1.
J.Biomol.Nmr, 45, 2009

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