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PDB: 3 results

6BY3
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BU of 6by3 by Molmil
Open and conductive conformation of KcsA-T75A mutant
Descriptor: Antibody Heavy Chain, Antibody Light Chain, DIACYL GLYCEROL, ...
Authors:Labro, A.J, Cortes, D.M, Tilegenova, C, Cuello, L.G.
Deposit date:2017-12-19
Release date:2018-05-09
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Inverted allosteric coupling between activation and inactivation gates in K+channels.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BY2
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BU of 6by2 by Molmil
Closed and deep-inactivated conformation of KcsA-T75A mutant
Descriptor: Antibody Heavy Chain, Antibody Light Chain, DIACYL GLYCEROL, ...
Authors:Labro, A.J, Cortes, D.M, Tilegenova, C, Cuello, L.G.
Deposit date:2017-12-19
Release date:2018-05-09
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Inverted allosteric coupling between activation and inactivation gates in K+channels.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7SQW
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BU of 7sqw by Molmil
Structure of the KcsA-W67F mutant with the activation gate in the closed conformation
Descriptor: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Fragment, KcsA potassium channel, ...
Authors:Cuello, L.G, Labro, A.J.
Deposit date:2021-11-07
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels.
Sci Adv, 8, 2022

221051

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