5CVC
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![BU of 5cvc by Molmil](/molmil-images/mine/5cvc) | Structure of maize serine racemase | 分子名称: | MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Serine racemase | 著者 | Song, Y, Zou, L, Fan, J. | 登録日 | 2015-07-26 | 公開日 | 2016-03-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of maize serine racemase with pyridoxal 5'-phosphate. Acta Crystallogr.,Sect.F, 72, 2016
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8QBG
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8QBF
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![BU of 8qbf by Molmil](/molmil-images/mine/8qbf) | Compact state - Pil1 dimer with lipid headgroups fitted in native eisosome lattice bound to plasma membrane microdomain | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PHOSPHOSERINE, Sphingolipid long chain base-responsive protein PIL1 | 著者 | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | 登録日 | 2023-08-24 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | CryoEM architecture of a native stretch-sensitive membrane microdomain To Be Published
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8QB9
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![BU of 8qb9 by Molmil](/molmil-images/mine/8qb9) | Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30) | 分子名称: | Sphingolipid long chain base-responsive protein PIL1 | 著者 | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | 登録日 | 2023-08-24 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | CryoEM architecture of a native stretch-sensitive membrane microdomain To Be Published
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8QBD
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![BU of 8qbd by Molmil](/molmil-images/mine/8qbd) | Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol, PI(4,5)P2 35:20:20:15:10) | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Sphingolipid long chain base-responsive protein PIL1 | 著者 | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | 登録日 | 2023-08-24 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | CryoEM architecture of a native stretch-sensitive membrane microdomain To Be Published
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8QB8
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8QB7
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8QBE
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8QBB
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![BU of 8qbb by Molmil](/molmil-images/mine/8qbb) | Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/-sterol (DOPC, DOPE, DOPS, PI(4,5)P2 50:20:20:10) | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Sphingolipid long chain base-responsive protein PIL1 | 著者 | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | 登録日 | 2023-08-24 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | CryoEM architecture of a native stretch-sensitive membrane microdomain To Be Published
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1TE6
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![BU of 1te6 by Molmil](/molmil-images/mine/1te6) | Crystal Structure of Human Neuron Specific Enolase at 1.8 angstrom | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Gamma enolase, ... | 著者 | Chai, G, Brewer, J, Lovelace, L, Aoki, T, Minor, W, Lebioda, L. | 登録日 | 2004-05-24 | 公開日 | 2004-09-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Expression, Purification and the 1.8 A Resolution Crystal Structure of Human Neuron Specific Enolase J.Mol.Biol., 341, 2004
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5CXD
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![BU of 5cxd by Molmil](/molmil-images/mine/5cxd) | 1.75 Angstrom resolution crystal structure of the apo-form acyl-carrier-protein synthase (AcpS) (acpS; purification tag off) from Staphylococcus aureus subsp. aureus COL in the I4 space group | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Holo-[acyl-carrier-protein] synthase, ... | 著者 | Halavaty, A.S, Minasov, G, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-07-28 | 公開日 | 2015-08-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | 1.75 Angstrom resolution crystal structure of the apo-form acyl-carrier-protein synthase (AcpS) (acpS; purification tag off) from Staphylococcus aureus subsp. aureus COL in the I4 space group To Be Published
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6W75
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![BU of 6w75 by Molmil](/molmil-images/mine/6w75) | 1.95 Angstrom Resolution Crystal Structure of NSP10 - NSP16 Complex from SARS-CoV-2 | 分子名称: | 2'-O-methyltransferase, FORMIC ACID, Non-structural protein 10, ... | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Wiersum, G, Godzik, A, Jaroszewski, L, Stogios, P.J, Skarina, T, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-03-18 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | 主引用文献 | High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design. Sci.Signal., 13, 2020
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2J95
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![BU of 2j95 by Molmil](/molmil-images/mine/2j95) | CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | 分子名称: | 5'-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-2,2'-BITHIOPHENE-5-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, ACTIVATED FACTOR XA LIGHT CHAIN, ... | 著者 | Chan, C, Borthwick, A.D, Brown, D, Campbell, M, Chaudry, L, Chung, C.W, Convery, M.A, Hamblin, J.N, Johnstone, L, Kelly, H.A, Kleanthous, S, Burns-Kurtis, C.L, Patikis, A, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Weston, H.E, Whitworth, C, Young, R.J, Zhou, P. | 登録日 | 2006-11-02 | 公開日 | 2007-03-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}Sulfonamides. J.Med.Chem., 50, 2007
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2IDN
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![BU of 2idn by Molmil](/molmil-images/mine/2idn) | NMR structure of a new modified Thrombin Binding Aptamer containing a 5'-5' inversion of polarity site | 分子名称: | 3'-D(P*GP*G*T)-5'-5'-D(P*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3' | 著者 | Randazzo, A, Martino, L, Virno, A, Mayol, L, Giancola, C. | 登録日 | 2006-09-15 | 公開日 | 2007-01-09 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A new modified thrombin binding aptamer containing a 5'-5' inversion of polarity site. Nucleic Acids Res., 34, 2006
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6VXG
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![BU of 6vxg by Molmil](/molmil-images/mine/6vxg) | Structure of the C-terminal Domain of RAGE and Its Inhibitor | 分子名称: | Advanced glycosylation end product-specific receptor, N-(4-{7-cyano-4-[(morpholin-4-yl)methyl]quinolin-2-yl}phenyl)acetamide | 著者 | Ramirez, L, Shekhtman, A. | 登録日 | 2020-02-21 | 公開日 | 2021-02-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice. Sci Transl Med, 13, 2021
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6P6X
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![BU of 6p6x by Molmil](/molmil-images/mine/6p6x) | Crystal structure of voltage-gated sodium channel NavAb G94C/Q150C mutant in the activated state | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | 登録日 | 2019-06-04 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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6PQ0
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![BU of 6pq0 by Molmil](/molmil-images/mine/6pq0) | LCP-embedded Proteinase K treated with MPD | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Bu, G, Zhu, L, Jing, L, Shi, D, Gonen, T, Liu, W, Nannenga, B.L. | 登録日 | 2019-07-08 | 公開日 | 2020-08-05 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2 Å) | 主引用文献 | Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED. Structure, 28, 2020
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6PQ4
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![BU of 6pq4 by Molmil](/molmil-images/mine/6pq4) | LCP-embedded Proteinase K treated with lipase | 分子名称: | CALCIUM ION, NITRATE ION, Proteinase K | 著者 | Bu, G, Zhu, L, Jing, L, Shi, D, Gonen, T, Liu, W, Nannenga, B.L. | 登録日 | 2019-07-08 | 公開日 | 2020-08-05 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2 Å) | 主引用文献 | Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED. Structure, 28, 2020
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5KO5
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![BU of 5ko5 by Molmil](/molmil-images/mine/5ko5) | Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with cytosine | 分子名称: | 1,2-ETHANEDIOL, 6-AMINOPYRIMIDIN-2(1H)-ONE, Purine nucleoside phosphorylase | 著者 | Torini, J.R, Romanello, L, Bird, L, Owens, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2016-06-29 | 公開日 | 2017-08-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs. PLoS ONE, 13, 2018
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7ATY
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![BU of 7aty by Molmil](/molmil-images/mine/7aty) | Solution NMR structure of the SH3 domain of human Caskin1 | 分子名称: | Caskin-1 | 著者 | Toke, O, Koprivanacz, K, Radnai, L, Mero, B, Juhasz, T, Liliom, K, Buday, L. | 登録日 | 2020-11-01 | 公開日 | 2021-02-03 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding. Cells, 10, 2021
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6PT2
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![BU of 6pt2 by Molmil](/molmil-images/mine/6pt2) | Crystal structure of the active delta opioid receptor in complex with the peptide agonist KGCHM07 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, Delta opioid receptor, ... | 著者 | Claff, T, Yu, J, Blais, V, Patel, N, Martin, C, Wu, L, Han, G.W, Holleran, B.J, Van der Poorten, O, Hanson, M.A, Sarret, P, Gendron, L, Cherezov, V, Katritch, V, Ballet, S, Liu, Z, Muller, C.E, Stevens, R.C. | 登録日 | 2019-07-14 | 公開日 | 2019-12-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Elucidating the active delta-opioid receptor crystal structure with peptide and small-molecule agonists. Sci Adv, 5, 2019
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5KO6
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![BU of 5ko6 by Molmil](/molmil-images/mine/5ko6) | Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with cytosine and ribose-1-phosphate | 分子名称: | 1-O-phosphono-alpha-D-ribofuranose, 6-AMINOPYRIMIDIN-2(1H)-ONE, Purine nucleoside phosphorylase | 著者 | Torini, J.R, Romanello, L, Bird, L, Owens, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2016-06-29 | 公開日 | 2017-08-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs. PLoS ONE, 13, 2018
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6Q8J
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![BU of 6q8j by Molmil](/molmil-images/mine/6q8j) | Nterminal domain of human SMU1 in complex with LSP641 | 分子名称: | 1-~{tert}-butyl-3-[6-(3,5-dimethoxyphenyl)-2-[[1-[1-(phenylmethyl)piperidin-4-yl]-1,2,3-triazol-4-yl]methylamino]pyrido[2,3-d]pyrimidin-7-yl]urea, WD40 repeat-containing protein SMU1 | 著者 | Tengo, L, Le Corre, L, Fournier, G, Ashraf, U, Busca, P, Rameix-Welti, M.-A, Gravier-Pelletier, C, Ruigrok, R.W.H, Jacob, Y, Vidalain, P.-O, Pietrancosta, N, Naffakh, N, McCarthy, A.A, Crepin, T. | 登録日 | 2018-12-14 | 公開日 | 2019-05-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy. Proc.Natl.Acad.Sci.USA, 116, 2019
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7ZJE
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![BU of 7zje by Molmil](/molmil-images/mine/7zje) | C16-2 | 分子名称: | Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein | 著者 | Zhang, L, Gourdon, P, Zygmunt, P.M. | 登録日 | 2022-04-10 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function. Nat Commun, 13, 2022
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7ZJG
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![BU of 7zjg by Molmil](/molmil-images/mine/7zjg) | Probenecid | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | 著者 | Zhang, L, Gourdon, P, Zygmunt, P.M. | 登録日 | 2022-04-11 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function. Nat Commun, 13, 2022
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