6FBX
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6TZC
| Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin | Descriptor: | Apoptosis regulator Bcl-2 homolog, Beclin-1, Maltose/maltodextrin-binding periplasmic protein, ... | Authors: | Banjara, S, Kvansakul, M, Hinds, M.G. | Deposit date: | 2019-08-12 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin. Viruses, 11, 2019
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4UF1
| Deerpox virus DPV022 in complex with Bak BH3 | Descriptor: | Antiapoptotic membrane protein, Bcl-2 homologous antagonist/killer, SULFATE ION | Authors: | Burton, D.R, Kvansakul, M. | Deposit date: | 2014-12-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis. Acta Crystallogr.,Sect.D, 71, 2015
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4UF2
| Deerpox virus DPV022 in complex with Bax BH3 | Descriptor: | Antiapoptotic membrane protein, Apoptosis regulator BAX | Authors: | Burton, D.R, Kvansakul, M. | Deposit date: | 2014-12-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis. Acta Crystallogr.,Sect.D, 71, 2015
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4UF3
| Deerpox virus DPV022 in complex with Bim BH3 | Descriptor: | Antiapoptotic membrane protein, Bcl-2-like protein 11 | Authors: | Burton, D.R, Kvansakul, M. | Deposit date: | 2014-12-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of Deerpox Virus-Mediated Inhibition of Apoptosis. Acta Crystallogr.,Sect.D, 71, 2015
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6B55
| Crystal structure of the Plant Defensin NaD1 complexed with phosphatidic acid | Descriptor: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, Flower-specific defensin, ... | Authors: | Jarva, M, Phan, K, Humble, C, Lay, F.T, Hulett, M, Kvansakul, M. | Deposit date: | 2017-09-28 | Release date: | 2018-05-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex. Nat Commun, 9, 2018
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6CS9
| Crystal structure of human beta-defensin 2 in complex with PIP2 | Descriptor: | Beta-defensin 4A, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | Authors: | Jarva, M, Phan, K, Lay, F.T, Humble, C, Hulett, M, Kvansakul, M. | Deposit date: | 2018-03-20 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Human beta-defensin 2 killsCandida albicansthrough phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization. Sci Adv, 4, 2018
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7JO7
| Crystal Structure of Human Scribble PDZ2 | Descriptor: | 1,2-ETHANEDIOL, Protein scribble homolog | Authors: | How, J.Y, Kvansakul, M. | Deposit date: | 2020-08-06 | Release date: | 2021-03-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Structural basis of the human Scribble-Vangl2 association in health and disease. Biochem.J., 478, 2021
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1GR3
| Structure of the human collagen X NC1 trimer | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, COLLAGEN X, ... | Authors: | Bogin, O, Kvansakul, M, Rom, E, Singer, J, Yayon, A, Hohenester, E. | Deposit date: | 2001-12-12 | Release date: | 2002-02-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insight Into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X Nc1 Domain Trimer. Structure, 10, 2002
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6MRY
| NoD173 plant defensin | Descriptor: | 1,2-ETHANEDIOL, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CHLORIDE ION, ... | Authors: | Caria, S, Kvansakul, M. | Deposit date: | 2018-10-15 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and functional characterization of the membrane-permeabilizing activity ofNicotiana occidentalisdefensin NoD173 and protein engineering to enhance oncolysis. Faseb J., 33, 2019
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7NTK
| PALS1 PDZ1 domain with SARS-CoV-2_E PBM complex | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Envelope small membrane protein, ... | Authors: | Javorsky, A, Kvansakul, M. | Deposit date: | 2021-03-10 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain. Commun Biol, 4, 2021
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7NTJ
| PALS1 PDZ1 domain with SARS-CoV-1_E PBM complex | Descriptor: | Envelope small membrane protein, MAGUK p55 subfamily member 5 | Authors: | Javorsky, A, Kvansakul, M. | Deposit date: | 2021-03-10 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain. Commun Biol, 4, 2021
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4UJ0
| Crystal structure of the tomato defensin TPP3 | Descriptor: | ACETATE ION, FLOWER-SPECIFIC GAMMA-THIONIN-LIKE PROTEIN/ACIDIC PROTEIN | Authors: | Richter, V, Lay, F.T, Hulett, M.D, Kvansakul, M. | Deposit date: | 2015-04-07 | Release date: | 2015-04-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Tomato Defensin Tpp3 Binds Phosphatidylinositol (4,5)-Bisphosphate Via a Conserved Dimeric Cationic Grip Conformation to Mediate Cell Lysis. Mol.Cell.Biol., 35, 2015
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7ADS
| Orf virus Apoptosis inhibitor ORFV125 | Descriptor: | 1,2-ETHANEDIOL, Apoptosis inhibitor, CHLORIDE ION, ... | Authors: | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | Deposit date: | 2020-09-16 | Release date: | 2021-10-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.22032046 Å) | Cite: | Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis. Biochem.J., 477, 2020
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7ADT
| Orf virus Apoptosis inhibitor ORFV125 | Descriptor: | 1,2-ETHANEDIOL, Apoptosis inhibitor, Apoptosis regulator BAX, ... | Authors: | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | Deposit date: | 2020-09-16 | Release date: | 2021-10-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.210037 Å) | Cite: | Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis. Biochem.J., 477, 2020
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6TQQ
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6TQP
| Structural insight into tanapoxvirus mediated inhibition of apoptosis | Descriptor: | 16L protein, Bcl-2-binding component 3, isoforms 1/2, ... | Authors: | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | Deposit date: | 2019-12-17 | Release date: | 2020-06-03 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.84940946 Å) | Cite: | Structural insight into tanapoxvirus-mediated inhibition of apoptosis. Febs J., 287, 2020
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6TRR
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4B4S
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6MTU
| Crystal structure of human Scribble PDZ1:pMCC complex | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ... | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | Deposit date: | 2018-10-22 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.141 Å) | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
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6MS1
| Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC | Descriptor: | 1,2-ETHANEDIOL, APC C-terminus peptide, Protein scribble homolog | Authors: | How, J.Y, Kvansakul, M, Caria, S, Humbert, P.O. | Deposit date: | 2018-10-16 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC. FEBS Lett., 593, 2019
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5WOU
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6MTV
| Crystal structure of human Scribble PDZ1:MCC complex | Descriptor: | Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, Protein scribble homolog, ... | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | Deposit date: | 2018-10-22 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
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2WUH
| Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide | Descriptor: | COLLAGEN PEPTIDE, DISCOIDIN DOMAIN RECEPTOR 2 | Authors: | Carafoli, F, Bihan, D, Stathopoulos, S, Konitsiotis, A.D, Kvansakul, M, Farndale, R.W, Leitinger, B, Hohenester, E. | Deposit date: | 2009-10-05 | Release date: | 2009-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2 Structure, 17, 2009
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4CQK
| Crystal structure of ligand-bound NaD1 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, FLOWER-SPECIFIC DEFENSIN, SULFATE ION, ... | Authors: | Lay, F.T, Mills, G.M, Poon, I.K.H, Baxter, A.A, Hulett, M.D, Kvansakul, M. | Deposit date: | 2014-02-17 | Release date: | 2014-04-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Phosphoinositide-Mediated Oligomerization of a Defensin Induces Cell Lysis. Elife, 3, 2014
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