8K3Y
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![BU of 8k3y by Molmil](/molmil-images/mine/8k3y) | The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I. | 登録日 | 2023-07-17 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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4FWD
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![BU of 4fwd by Molmil](/molmil-images/mine/4fwd) | Crystal structure of the Lon-like protease MtaLonC in complex with bortezomib | 分子名称: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, TTC1975 peptidase | 著者 | Chang, C.I, Kuo, C.I, Huang, K.F. | 登録日 | 2012-06-30 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
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4FW9
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![BU of 4fw9 by Molmil](/molmil-images/mine/4fw9) | Crystal structure of the Lon-like protease MtaLonC | 分子名称: | PHOSPHATE ION, TTC1975 peptidase | 著者 | Chang, C.I, Ihara, K, Kuo, C.I, Huang, K.F, Wakatsuki, S. | 登録日 | 2012-06-30 | 公開日 | 2013-06-26 | 最終更新日 | 2013-09-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
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4FWH
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![BU of 4fwh by Molmil](/molmil-images/mine/4fwh) | Crystal structure of the Lon-like protease MtaLonC in complex with MG262 | 分子名称: | N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-L-leucinamide, PHOSPHATE ION, TTC1975 peptidase | 著者 | Chang, C.I, Kuo, C.I, Huang, K.F. | 登録日 | 2012-07-01 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
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4FWV
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![BU of 4fwv by Molmil](/molmil-images/mine/4fwv) | Crystal structure of the N-terminal domain of the Lon-like protease MtaLonC | 分子名称: | SULFATE ION, TTC1975 peptidase | 著者 | Chang, C.I, Li, J.K, Kuo, C.I, Huang, K.F. | 登録日 | 2012-07-02 | 公開日 | 2013-06-26 | 最終更新日 | 2014-03-12 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The N-terminal substrate-recognition domain of a LonC protease exhibits structural and functional similarity to cytosolic chaperones Acta Crystallogr.,Sect.D, 69, 2013
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4FWG
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![BU of 4fwg by Molmil](/molmil-images/mine/4fwg) | Crystal structure of the Lon-like protease MtaLonC in complex with lactacystin | 分子名称: | Omuralide, open form, PHOSPHATE ION, ... | 著者 | Chang, C.I, Kuo, C.I, Huang, K.F. | 登録日 | 2012-07-01 | 公開日 | 2013-06-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structures of an ATP-independent Lon-like protease and its complexes with covalent inhibitors Acta Crystallogr.,Sect.D, 69, 2013
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7YPJ
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![BU of 7ypj by Molmil](/molmil-images/mine/7ypj) | Spiral pentamer of the substrate-free Lon protease with a S678A mutation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPI
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![BU of 7ypi by Molmil](/molmil-images/mine/7ypi) | Spiral hexamer of the substrate-free Lon protease with a Y224S mutation | 分子名称: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPH
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![BU of 7yph by Molmil](/molmil-images/mine/7yph) | Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation | 分子名称: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPK
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![BU of 7ypk by Molmil](/molmil-images/mine/7ypk) | Close-ring hexamer of the substrate-bound Lon protease with an S678A mutation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, alpha-S1-casein | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7EV4
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![BU of 7ev4 by Molmil](/molmil-images/mine/7ev4) | Crystal structure of the Lon-like protease MtaLonC with S582A mutation in complex with F-b20-Q | 分子名称: | Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | 登録日 | 2021-05-20 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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7EUY
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![BU of 7euy by Molmil](/molmil-images/mine/7euy) | Crystal structure of the Lon-like protease MtaLonC with D582A mutation in complex with substrate polypeptide | 分子名称: | ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | 登録日 | 2021-05-19 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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7EV6
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![BU of 7ev6 by Molmil](/molmil-images/mine/7ev6) | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with F-b20-Q | 分子名称: | Endopeptidase La, F-b20-Q peptide {ortho-aminobenzoic acid (Abz)- QLRSLNGEWRFAWFPAPEAV[Tyr(3-NO2)]A}, PHOSPHATE ION | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | 登録日 | 2021-05-20 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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7EUX
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![BU of 7eux by Molmil](/molmil-images/mine/7eux) | Crystal structure of the Lon-like protease MtaLonC with D581A mutation in complex with substrate polypeptide | 分子名称: | ALA-PRO-GLU-ALA-VAL, Endopeptidase La, PHOSPHATE ION | 著者 | Hsieh, K.Y, Kuo, C.I, Su, S.C, Huang, K.F, Chang, C.I. | 登録日 | 2021-05-19 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex. Sci Adv, 7, 2021
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