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PDB: 121 件
3ZJE
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BU of 3zje by Molmil
A20 OTU domain in reversibly oxidised (SOH) state
分子名称: 1,2-ETHANEDIOL, A20P50, CHLORIDE ION
著者Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D.
登録日2013-01-17
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation
Nat.Commun., 4, 2013
3ZNV
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BU of 3znv by Molmil
Crystal structure of the OTU domain of OTULIN at 1.3 Angstroms.
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
5OE7
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BU of 5oe7 by Molmil
Structure of OTULIN bound to the Met1-linked diubiquitin activity probe
分子名称: Polyubiquitin-C, Ubiquitin thioesterase otulin
著者Elliott, P.R, Komander, D.
登録日2017-07-07
公開日2017-09-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24, 2017
3ZNZ
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BU of 3znz by Molmil
Crystal structure of OTULIN OTU domain (C129A) in complex with Met1- di ubiquitin
分子名称: POLYUBIQUITIN-C, PROTEIN FAM105B, SULFATE ION
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZJD
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BU of 3zjd by Molmil
A20 OTU domain in reduced, active state at 1.87 A resolution
分子名称: 1,2-ETHANEDIOL, A20P50, CHLORIDE ION
著者Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D.
登録日2013-01-17
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation
Nat.Commun., 4, 2013
3ZRH
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BU of 3zrh by Molmil
Crystal structure of the Lys29, Lys33-linkage-specific TRABID OTU deubiquitinase domain reveals an Ankyrin-repeat ubiquitin binding domain (AnkUBD)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, UBIQUITIN THIOESTERASE ZRANB1
著者Licchesi, J.D.F, Akutsu, M, Komander, D.
登録日2011-06-16
公開日2011-12-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献An Ankyrin-Repeat Ubiquitin-Binding Domain Determines Trabid'S Specificity for Atypical Ubiquitin Chains.
Nat.Struct.Mol.Biol., 19, 2011
5OHL
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BU of 5ohl by Molmil
K6-specific affimer bound to K6 diUb
分子名称: GLYCEROL, K6-specific affimer, POLYETHYLENE GLYCOL (N=34), ...
著者Michel, M.A, Komander, D.
登録日2017-07-17
公開日2017-10-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Mol. Cell, 68, 2017
3ZJF
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BU of 3zjf by Molmil
A20 OTU domain with irreversibly oxidised Cys103 from 270 min H2O2 soak.
分子名称: A20P50, CHLORIDE ION
著者Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D.
登録日2013-01-17
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation
Nat.Commun., 4, 2013
3ZNX
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BU of 3znx by Molmil
Crystal structure of the OTU domain of OTULIN D336A mutant
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZJG
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BU of 3zjg by Molmil
A20 OTU domain with irreversibly oxidised Cys103 from 60 min H2O2 soak.
分子名称: CHLORIDE ION, TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3
著者Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D.
登録日2013-01-17
公開日2013-03-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation
Nat.Commun., 4, 2013
3VVW
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BU of 3vvw by Molmil
NDP52 in complex with LC3C
分子名称: Calcium-binding and coiled-coil domain-containing protein 2, Microtubule-associated proteins 1A/1B light chain 3C
著者Akutsu, M, Muhlinen, N.V, Randow, F, Komander, D.
登録日2012-07-28
公開日2013-02-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
Mol.Cell, 48, 2012
3ZNH
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BU of 3znh by Molmil
Crimean Congo Hemorrhagic Fever Virus OTU domain in complex with ubiquitin-propargyl.
分子名称: POLYUBIQUITIN-B, UBIQUITIN THIOESTERASE
著者Ekkebus, R, vanKasteren, S.I, Kulathu, Y, Scholten, A, Berlin, I, deJong, A, Goerdayal, G, Neefjes, J, Heck, A.J.R, Komander, D, Ovaa, H.
登録日2013-02-14
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献On Terminal Alkynes that Can React with Active-Site Cysteine Nucleophiles in Proteases.
J.Am.Chem.Soc., 135, 2013
3ZLZ
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BU of 3zlz by Molmil
Lys6-linked tri-ubiquitin
分子名称: UBIQUITIN, ZINC ION
著者Hospenthal, M.K, Freund, S.M.V, Komander, D.
登録日2013-02-04
公開日2013-04-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Assembly, Analysis and Architecture of Atypical Ubiquitin Chains
Nat.Struct.Mol.Biol., 20, 2013
2XK5
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BU of 2xk5 by Molmil
Crystal structure of K6-linked diubiquitin
分子名称: UBIQUITIN, ZINC ION
著者Virdee, S, Chin, J.W, Komander, D.
登録日2010-07-07
公開日2010-08-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Engineered Diubiquitin Synthesis Reveals K29-Isopeptide Specificity of an Otu Deubiquitinase
Nat.Chem.Biol., 6, 2010
2XEW
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BU of 2xew by Molmil
Crystal structure of K11-linked diubiquitin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CITRATE ANION, ...
著者Bremm, A, Freund, S.M.V, Komander, D.
登録日2010-05-18
公開日2010-07-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lys11-Linked Ubiquitin Chains Adopt Compact Conformations and are Preferentially Hydrolyzed by the Deubiquitinase Cezanne
Nat.Struct.Mol.Biol., 17, 2010
1UPQ
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BU of 1upq by Molmil
Crystal structure of the pleckstrin homology (PH) domain of PEPP1
分子名称: PEPP1, SULFATE ION
著者Milburn, C.C, Komander, D, Deak, M, Alessi, D.R, van Aalten, D.M.F.
登録日2003-10-09
公開日2004-10-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structure of the Pleckstrin Homology Domain of Pepp1
To be Published
2Y5B
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BU of 2y5b by Molmil
Structure of USP21 in complex with linear diubiquitin-aldehyde
分子名称: SULFATE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21, ...
著者Ye, Y, Akutsu, M, Reyes-Turcu, F, Enchev, R.I, Wilkinson, K.D, Komander, D.
登録日2011-01-12
公開日2012-01-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Polyubiquitin Binding and Cross-Reactivity in the Usp Domain Deubiquitinase Usp21.
Embo Rep., 12, 2011
1UPR
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BU of 1upr by Molmil
Crystal structure of the PEPP1 pleckstrin homology domain in complex with Inositol 1,3,4,5-tetrakisphosphate
分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4
著者Milburn, C.C, Komander, D, Deak, M, Alessi, D.R, Van Aalten, D.M.F.
登録日2003-10-10
公開日2004-10-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal Structure of the Pleckstrin Homology Domain of Pepp1
To be Published
2WX1
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BU of 2wx1 by Molmil
TAB2 NZF DOMAIN IN COMPLEX WITH Lys63-linked tri-ubiquitin, P212121
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 2, UBIQUITIN, ZINC ION
著者Kulathu, Y, Akutsu, M, Bremm, A, Hofmann, K, Komander, D.
登録日2009-10-30
公開日2009-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain
Nat.Struct.Mol.Biol., 16, 2009
2WWZ
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BU of 2wwz by Molmil
TAB2 NZF DOMAIN IN COMPLEX WITH Lys63-linked di-ubiquitin, P212121
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 2, UBIQUITIN, ZINC ION
著者Kulathu, Y, Akutsu, M, Bremm, A, Hofmann, K, Komander, D.
登録日2009-10-30
公開日2009-11-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain
Nat.Struct.Mol.Biol., 16, 2009
2WX0
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BU of 2wx0 by Molmil
TAB2 NZF DOMAIN IN COMPLEX WITH Lys63-linked di-ubiquitin, P21
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 2, UBIQUITIN, ZINC ION
著者Kulathu, Y, Akutsu, M, Bremm, A, Hofmann, K, Komander, D.
登録日2009-10-30
公開日2009-11-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain
Nat.Struct.Mol.Biol., 16, 2009

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