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PDB: 39 results
4PHP
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BU of 4php by Molmil
Structure of human DNA polymerase beta complexed with T in the template base paired with incoming non-hydrolyzable GTP and MANGANESE
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-05-06
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The spontaneous base substitution mechanisms of human DNA polymerase beta
To Be Published
4PGY
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BU of 4pgy by Molmil
Structure of human DNA polymerase beta complexed with a nicked DNA containing a GT at N-1 position and GC at N position
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-05-03
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The spontaneous base substitution mechanisms of human DNA polymerase beta
To Be Published
4PHA
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BU of 4pha by Molmil
Structure of human DNA polymerase beta complexed with A in the template base paired with incoming non-hydrolyzable CTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-05-05
Release date:2014-09-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase beta.
Nucleic Acids Res., 42, 2015
4PHE
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BU of 4phe by Molmil
Structure of human DNA polymerase beta complexed with T in the template base paired with incoming non-hydrolyzable GTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-05-06
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The spontaneous base substitution mechanisms of human DNA polymerase beta
To Be Published
4PH5
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BU of 4ph5 by Molmil
Structure of human DNA polymerase beta complexed with a nicked DNA containing a AC at N-1 position and GC at N position
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-05-04
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The spontaneous base substitution mechanisms of human DNA polymerase beta
To Be Published
4PHD
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BU of 4phd by Molmil
Structure of human DNA polymerase beta complexed with A in the template base paired with incoming non-hydrolyzable CTP and MANGANESE
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-05-06
Release date:2014-09-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase beta.
Nucleic Acids Res., 42, 2015
4M47
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BU of 4m47 by Molmil
structure of human DNA polymerase complexed with 8-BrG in the template base paired with incoming non-hydrolyzable GTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA polymerase beta, MAGNESIUM ION, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-06
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4MFC
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BU of 4mfc by Molmil
Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable CTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase beta, MAGNESIUM ION, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-27
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
4M2Y
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BU of 4m2y by Molmil
Structure of human DNA polymerase beta complexed with 8-BrG as the template base in a 1-nucleotide gapped DNA
Descriptor: DNA polymerase beta, SODIUM ION, down-primer, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-05
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
4MFA
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BU of 4mfa by Molmil
Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming TTP
Descriptor: DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-27
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structures of human DNA polymerase beta inserting bases opposite templating O6MG
To be Published
4MF2
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BU of 4mf2 by Molmil
Structure of human DNA polymerase beta complexed with O6MG as the template base in a 1-nucleotide gapped DNA
Descriptor: DNA polymerase beta, SODIUM ION, synthetic downstream primer, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-27
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
4MFF
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BU of 4mff by Molmil
Structure of human DNA polymerase beta complexed with O6MG in the template base paired with incoming non-hydrolyzable TTP
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA polymerase beta, MAGNESIUM ION, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-27
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
4MF8
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BU of 4mf8 by Molmil
Structure of human DNA polymerase beta complexed with nicked DNA containing a mismatched template O6MG and incoming CTP
Descriptor: DNA polymerase beta, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-27
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structures of human DNA polymerase beta inserting bases opposite templating O6MG
To be Published
4P2H
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BU of 4p2h by Molmil
Structure of human DNA polymerase complexed with N7MG in the template opposite to incoming non-hydrolyzable TTP with manganese in the active site
Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Lee, S, Koag, M.C.
Deposit date:2014-03-04
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.987 Å)
Cite:Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Nucleic Acids Res., 42, 2014
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數據於2024-07-10公開中

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