7NST
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![BU of 7nst by Molmil](/molmil-images/mine/7nst) | ColicinE9 partial translocation complex | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | Deposit date: | 2021-03-08 | Release date: | 2021-08-11 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF. Embo J., 40, 2021
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1V13
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![BU of 1v13 by Molmil](/molmil-images/mine/1v13) | |
7NSU
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![BU of 7nsu by Molmil](/molmil-images/mine/7nsu) | ColicinE9 intact translocation complex | Descriptor: | Colicin-E9, Outer membrane protein F, Tol-Pal system protein TolB, ... | Authors: | Webby, M.N, Kleanthous, C, Lukoyanova, N, Housden, N.G. | Deposit date: | 2021-03-08 | Release date: | 2021-08-11 | Last modified: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Porin threading drives receptor disengagement and establishes active colicin transport through Escherichia coli OmpF. Embo J., 40, 2021
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1GXG
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![BU of 1gxg by Molmil](/molmil-images/mine/1gxg) | Non-cognate protein-protein interactions: the NMR structure of the colicin E8 inhibitor protein Im8 and its interaction with the DNase domain of colicin E9 | Descriptor: | COLICIN E8 IMMUNITY PROTEIN | Authors: | Le Duff, C.S, Videler, H, Boetzel, R, Czisch, M, James, R, Kleanthous, C, Moore, G.R. | Deposit date: | 2002-04-04 | Release date: | 2002-05-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Non-Cognate Protein-Protein Interaction: The NMR Structure of the Colicin E8 Inhibitor Protein Im8 and its Interaction with the DNase Domain of Colicin E9 To be Published
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1FSJ
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![BU of 1fsj by Molmil](/molmil-images/mine/1fsj) | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN | Descriptor: | COLICIN E9, PHOSPHATE ION, ZINC ION | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.R, James, R, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2000-09-11 | Release date: | 2003-06-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the E9 DNase domain in comparison with the inhibited structure of the E9 DNase/Im9 complex To be Published
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1FR2
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![BU of 1fr2 by Molmil](/molmil-images/mine/1fr2) | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A) | Descriptor: | COLICIN E9, COLICIN E9 IMMUNITY PROTEIN, PHOSPHATE ION, ... | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2000-09-07 | Release date: | 2003-06-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A) To be Published
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1E44
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![BU of 1e44 by Molmil](/molmil-images/mine/1e44) | ribonuclease domain of colicin E3 in complex with its immunity protein | Descriptor: | 1,2-ETHANEDIOL, COLICIN E3, IMMUNITY PROTEIN | Authors: | Carr, S, Walker, D, James, R, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2000-06-28 | Release date: | 2001-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibition of a Ribosome Inactivating Ribonuclease: The Crystal Structure of the Cytotoxic Domain of Colicin E3 in Complex with its Immunity Protein Structure, 8, 2000
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2XDJ
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![BU of 2xdj by Molmil](/molmil-images/mine/2xdj) | |
1T3O
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![BU of 1t3o by Molmil](/molmil-images/mine/1t3o) | Solution structure of CsrA, a bacterial carbon storage regulatory protein | Descriptor: | Carbon storage regulator | Authors: | Koharudin, L.M.I, Georgiou, T, Kleanthous, C, Geoffrey, R, Kaptein, R, Boelens, R. | Deposit date: | 2004-04-27 | Release date: | 2005-10-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A model for RNA binding by the bacterial carbon storage regulatory protein, CsrA To be Published
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1EMV
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![BU of 1emv by Molmil](/molmil-images/mine/1emv) | CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS) | Descriptor: | COLICIN E9, IMMUNITY PROTEIN IM9, PHOSPHATE ION | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C. | Deposit date: | 2000-03-20 | Release date: | 2000-09-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes. J.Mol.Biol., 301, 2000
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1H3L
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![BU of 1h3l by Molmil](/molmil-images/mine/1h3l) | N-terminal fragment of SigR from Streptomyces coelicolor | Descriptor: | RNA POLYMERASE SIGMA FACTOR | Authors: | Li, W, Stevenson, C.E.M, Burton, N, Jakimowicz, P, Paget, M.S.B, Buttner, M.J, Lawson, D.M, Kleanthous, C. | Deposit date: | 2002-09-10 | Release date: | 2002-10-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.375 Å) | Cite: | Identification and Structure of the Anti-Sigma Factor-Binding Domain of the Disulfide-Stress Regulated Sigma Factor Sigma(R) from Streptomyces Coelicolor J.Mol.Biol., 323, 2002
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1GXH
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![BU of 1gxh by Molmil](/molmil-images/mine/1gxh) | Colicin E8 DNAse immunity protein: Im8 | Descriptor: | COLICIN E8 IMMUNITY PROTEIN | Authors: | Leduff, C.S, Videler, H, Boetzel, R, Czisch, M, James, R, Kleanthous, C, Moore, G.R. | Deposit date: | 2002-04-05 | Release date: | 2002-05-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Non-Cognate Protein-Protein Interaction: The NMR Structure of the Colicin E8 Inhibitor Protein Im8 and its Interaction with the DNase Domain of Colicin E9 To be Published
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2GZG
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![BU of 2gzg by Molmil](/molmil-images/mine/2gzg) | Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (Y55F) | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2006-05-11 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y55F) To be Published
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2GZI
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![BU of 2gzi by Molmil](/molmil-images/mine/2gzi) | Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A) | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2006-05-11 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (V34A) To be Published
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2GZF
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![BU of 2gzf by Molmil](/molmil-images/mine/2gzf) | Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F) | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2006-05-11 | Release date: | 2007-07-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y54F) To be Published
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2GZJ
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![BU of 2gzj by Molmil](/molmil-images/mine/2gzj) | Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (D51A) | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2006-05-11 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (D51A) To be Published
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2GZE
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![BU of 2gze by Molmil](/molmil-images/mine/2gze) | Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y55A) | Descriptor: | Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ... | Authors: | Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M. | Deposit date: | 2006-05-11 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Complex of
the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y55A) To be Published
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1E0H
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![BU of 1e0h by Molmil](/molmil-images/mine/1e0h) | Inhibitor Protein Im9 bound to its partner E9 DNase | Descriptor: | IMMUNITY PROTEIN FOR COLICIN E9 | Authors: | Boetzel, R, Czisch, M, Kaptein, R, Hemmings, A.M, James, R, Kleanthous, C, Moore, G.R. | Deposit date: | 2000-03-28 | Release date: | 2000-10-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR investigation of the interaction of the inhibitor protein Im9 with its partner DNase. Protein Sci., 9, 2000
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2WPT
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![BU of 2wpt by Molmil](/molmil-images/mine/2wpt) | The crystal structure of Im2 in complex with colicin E9 DNase | Descriptor: | COLICIN-E2 IMMUNITY PROTEIN, COLICIN-E9, GLYCEROL, ... | Authors: | Meenan, N.A, Sharma, A, Fleishman, S.J, Macdonald, C.J, Boetzel, R, Moore, G.R, Baker, D, Kleanthous, C. | Deposit date: | 2009-08-10 | Release date: | 2010-06-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The Structural and Energetic Basis for High Selectivity in a High-Affinity Protein-Protein Interaction. Proc.Natl.Acad.Sci.USA, 107, 2010
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2WZ7
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![BU of 2wz7 by Molmil](/molmil-images/mine/2wz7) | Crystal structure of the N-terminal domain of E.coli YbgF | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | Authors: | Krachler, A.M, Sharma, A, Kleanthous, C. | Deposit date: | 2009-11-24 | Release date: | 2010-09-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Tola Modulates the Oligomeric Status of Ybgf in the Bacterial Periplasm. J.Mol.Biol., 403, 2010
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2XEV
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![BU of 2xev by Molmil](/molmil-images/mine/2xev) | |
2W8B
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![BU of 2w8b by Molmil](/molmil-images/mine/2w8b) | Crystal structure of processed TolB in complex with Pal | Descriptor: | ACETATE ION, GLYCEROL, PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, ... | Authors: | Sharma, A, Bonsor, D.A, Kleanthous, C. | Deposit date: | 2009-01-15 | Release date: | 2009-02-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Allosteric Beta-Propeller Signalling in Tolb and its Manipulation by Translocating Colicins. Embo J., 28, 2009
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2IVZ
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![BU of 2ivz by Molmil](/molmil-images/mine/2ivz) | Structure of TolB in complex with a peptide of the colicin E9 T- domain | Descriptor: | CALCIUM ION, COLICIN-E9, PROTEIN TOLB | Authors: | Loftus, S.R, Walker, D, Mate, M.J, Bonsor, D.A, James, R, Moore, G.R, Kleanthous, C. | Deposit date: | 2006-06-23 | Release date: | 2006-08-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Competitive Recruitment of the Periplasmic Translocation Portal Tolb by a Natively Disordered Domain of Colicin E9 Proc.Natl.Acad.Sci.USA, 103, 2006
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2WQH
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![BU of 2wqh by Molmil](/molmil-images/mine/2wqh) | Crystal structure of CTPR3Y3 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | Authors: | Krachler, A.M, Sharma, A, Kleanthous, C. | Deposit date: | 2009-08-21 | Release date: | 2010-04-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Self-association of TPR domains: Lessons learned from a designed, consensus-based TPR oligomer. Proteins, 78, 2010
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2VLN
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![BU of 2vln by Molmil](/molmil-images/mine/2vln) | N75A mutant of E9 DNase domain in complex with Im9 | Descriptor: | COLICIN E9, COLICIN-E9 IMMUNITY PROTEIN, MALONIC ACID | Authors: | Keeble, A.H, Joachimiak, L.A, Mate, M.J, Meenan, N, Kirkpatrick, N, Baker, D, Kleanthous, C. | Deposit date: | 2008-01-15 | Release date: | 2008-05-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases. J.Mol.Biol., 379, 2008
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