5KMG
 
 | | Near-atomic cryo-EM structure of PRC1 bound to the microtubule | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E. | | 登録日 | 2016-06-27 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Near-atomic cryo-EM structure of PRC1 bound to the microtubule.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6PE2
 | | Drosophila P element transposase strand transfer complex | | 分子名称: | DNA (27-MER), DNA (5'-D(P*CP*GP*AP*AP*CP*TP*AP*TP*A)-3'), DNA (56-MER), ... | | 著者 | Kellogg, E.H, Nogales, E, Ghanim, G, Rio, D.C. | | 登録日 | 2019-06-19 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts.
Nat.Struct.Mol.Biol., 26, 2019
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6P5A
 | | Drosophila P element transposase strand transfer complex | | 分子名称: | DNA (44-MER), DNA (5'-D(P*AP*GP*GP*TP*GP*GP*TP*CP*CP*CP*GP*TP*CP*GP*G)-3'), DNA (5'-D(P*CP*GP*AP*AP*CP*TP*AP*TP*A)-3'), ... | | 著者 | Kellogg, E.H, Nogales, E, Ghanim, G, Rio, D.C. | | 登録日 | 2019-05-30 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts.
Nat.Struct.Mol.Biol., 26, 2019
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5SYF
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5SYE
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5SYG
 | | Cryo-EM reconstruction of zampanolide-bound microtubule | | 分子名称: | (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Kellogg, E.H, Hejab, N.M.A, Nogales, E. | | 登録日 | 2016-08-11 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
J. Mol. Biol., 429, 2017
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5SYC
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7M99
 | | ATPgS bound TnsC filament from ShCAST system | | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | 著者 | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | | 登録日 | 2021-03-30 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for target site selection in RNA-guided DNA transposition systems.
Science, 373, 2021
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7M9A
 | | ADP-AlF3 bound TnsC structure from ShCAST system | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (27-MER), TnsC | | 著者 | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | | 登録日 | 2021-03-30 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for target site selection in RNA-guided DNA transposition systems.
Science, 373, 2021
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7M9C
 | | ADP-AlF3 bound TnsC structure in open form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (34-MER), TnsC | | 著者 | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | | 登録日 | 2021-03-30 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis for target site selection in RNA-guided DNA transposition systems.
Science, 373, 2021
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7M9B
 | | ADP-AlF3 bound TnsC structure in closed form | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (27-MER), TnsC | | 著者 | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | | 登録日 | 2021-03-30 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for target site selection in RNA-guided DNA transposition systems.
Science, 373, 2021
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8GI1
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8EA4
 | | V-K CAST Transpososome from Scytonema hofmanni, minor configuration | | 分子名称: | 30S ribosomal protein S15, ADENOSINE-5'-TRIPHOSPHATE, Cas12k, ... | | 著者 | Rizo, A.R, Park, J.-U, Tsai, A.W, Kellogg, E.K. | | 登録日 | 2022-08-27 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex.
Nature, 613, 2023
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7U5E
 | | I-F3b Cascade-TniQ partial R-loop complex | | 分子名称: | Cas6, Cas7, Cas8/5, ... | | 著者 | Park, J.U, Mehrotra, E, Kellogg, E.H. | | 登録日 | 2022-03-02 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | | 主引用文献 | Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition.
Mol.Cell, 83, 2023
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7U5D
 | | I-F3b Cascade-TniQ full R-loop complex | | 分子名称: | Cas6, Cas7, Cas8/5, ... | | 著者 | Park, J.U, Mehrotra, E, Kellogg, E.H. | | 登録日 | 2022-03-02 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Multiple adaptations underly co-option of a CRISPR surveillance complex for RNA-guided DNA transposition.
Mol.Cell, 83, 2023
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7N6I
 | | ATP-bound TnsC-TniQ complex from ShCAST system | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Park, J, Tsai, A.W.L, Mehrotra, E, Kellogg, E.H. | | 登録日 | 2021-06-08 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for target site selection in RNA-guided DNA transposition systems.
Science, 373, 2021
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8EA3
 | | V-K CAST Transpososome from Scytonema hofmanni, major configuration | | 分子名称: | 30S ribosomal protein S15, ADENOSINE-5'-TRIPHOSPHATE, Cas12k, ... | | 著者 | Rizo, A.N, Park, J.-U, Tsai, A.W, Kellogg, E.H. | | 登録日 | 2022-08-27 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex.
Nature, 613, 2023
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7SVV
 | | TnsBctd-TnsC complex | | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ... | | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | | 登録日 | 2021-11-19 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7SVW
 | | Strand-transfer complex of TnsB from ShCAST | | 分子名称: | MAGNESIUM ION, STC_LE_For, STC_LE_Rev1, ... | | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | | 登録日 | 2021-11-19 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6CVN
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6CVJ
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7SVU
 | | TnsBctd-TnsC-TniQ complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (28-MER), DNA (29-MER), ... | | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | | 登録日 | 2021-11-19 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex
Nature, 613, 2023
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3J6E
 | | Energy minimized average structure of Microtubules stabilized by GmpCpp | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | 登録日 | 2014-02-18 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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3J6F
 | | Minimized average structure of GDP-bound dynamic microtubules | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | 登録日 | 2014-02-19 | | 公開日 | 2014-06-04 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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3J6G
 | | Minimized average structure of microtubules stabilized by taxol | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | 登録日 | 2014-02-19 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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