6JIB
| Human MTHFD2 in complex with DS44960156 | Descriptor: | 4-(5-oxo-1,5-dihydro-2H-[1]benzopyrano[3,4-c]pyridine-3(4H)-carbonyl)benzoic acid, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, ... | Authors: | Suzuki, M, Matsui, Y, Kawai, J. | Deposit date: | 2019-02-20 | Release date: | 2019-06-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold. Acs Med.Chem.Lett., 10, 2019
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6JID
| Human MTHFD2 in complex with Compound 1 | Descriptor: | 5-(4-oxo-2-phenyl-1,5,7,8-tetrahydropyrido[4,3-d]pyrimidine-6(4H)-carbonyl)-1,3-dihydro-2H-2lambda~6~,1-benzothiazole-2,2-dione, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, ... | Authors: | Suzuki, M, Matsui, Y, Matsuhashi, N, Kawai, J. | Deposit date: | 2019-02-20 | Release date: | 2019-06-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold. Acs Med.Chem.Lett., 10, 2019
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6KG2
| Human MTHFD2 in complex with Compound 18 | Descriptor: | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, N-[2-chloranyl-4-[[7-methyl-8-(4-methylpiperazin-1-yl)-5-oxidanylidene-2,4-dihydro-1H-chromeno[3,4-c]pyridin-3-yl]carbonyl]phenyl]methanesulfonamide, ... | Authors: | Suzuki, M, Matsui, Y, Ota, M, Kawai, J. | Deposit date: | 2019-07-10 | Release date: | 2019-11-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with in Vivo Antitumor Activity. J.Med.Chem., 62, 2019
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1UFN
| Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik) | Descriptor: | putative nuclear protein homolog 5830484A20Rik | Authors: | Tochio, N, Kobayashi, N, Koshiba, S, Kigawa, T, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-02 | Release date: | 2004-06-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik) To be Published
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1UG7
| Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806 | Descriptor: | 2610208M17Rik protein | Authors: | Li, H, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Shirouzu, M, Terada, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-13 | Release date: | 2004-08-17 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806 To be Published
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1UH6
| Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06 | Descriptor: | ubiquitin-like 5 | Authors: | Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-25 | Release date: | 2003-12-25 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06 To be Published
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1UHS
| Solution structure of mouse homeodomain-only protein HOP | Descriptor: | homeodomain only protein | Authors: | Saito, K, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-07-10 | Release date: | 2004-07-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of mouse homeodomain-only protein HOP To be Published
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1UHR
| Solution structure of the SWIB domain of mouse BRG1-associated factor 60a | Descriptor: | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily D member 1 | Authors: | Yamada, K, Saito, K, Nameki, N, Inoue, M, Koshiba, S, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-07-09 | Release date: | 2004-08-24 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the SWIB domain of mouse BRG1-associated factor 60a To be Published
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1UHW
| Solution structure of the DEP domain of mouse pleckstrin | Descriptor: | Pleckstrin | Authors: | Inoue, K, Yoshida, M, Hatta, R, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-07-11 | Release date: | 2004-01-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the DEP domain of mouse pleckstrin To be Published
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1V9J
| Solution structure of a BolA-like protein from Mus musculus | Descriptor: | BolA-like protein RIKEN cDNA 1110025L05 | Authors: | Kasai, T, Inoue, M, Koshiba, S, Yabuki, T, Aoki, M, Nunokawa, E, Seki, E, Matsuda, T, Matsuda, N, Tomo, Y, Shirouzu, M, Terada, T, Obayashi, N, Hamana, H, Shinya, N, Tatsuguchi, A, Yasuda, S, Yoshida, M, Hirota, H, Matsuo, Y, Tani, K, Suzuki, H, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-01-26 | Release date: | 2004-02-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a BolA-like protein from Mus musculus Protein Sci., 13, 2004
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1UG8
| NMR structure of the R3H domain from Poly(A)-specific Ribonuclease | Descriptor: | Poly(A)-specific Ribonuclease | Authors: | Nagata, T, Muto, Y, Hayami, N, Uda, H, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-15 | Release date: | 2004-08-17 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR structure of the R3H domain from Poly(A)-specific Ribonuclease To be Published
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1UG2
| Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain | Descriptor: | 2610100B20Rik gene product | Authors: | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-11 | Release date: | 2004-06-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain To be Published
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1UGJ
| Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16 | Descriptor: | RIKEN cDNA 2310057J16 protein | Authors: | Nagashima, T, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-16 | Release date: | 2004-08-03 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16 To be Published
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1UGO
| Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5 | Descriptor: | Bcl2-associated athanogene 5 | Authors: | Endoh, H, Hayashi, F, Seimiya, K, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-17 | Release date: | 2004-08-03 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange Structure, 18, 2010
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