6YJJ
 
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6YJK
 | | Structure of CYRI-B (FAM49B) from Rhincodon typus | | Descriptor: | CYRI-B (FAM49B) | | Authors: | Kaplan, E. | | Deposit date: | 2020-04-03 | | Release date: | 2020-10-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Structure of CYRI-B (FAM49B), a key regulator of cellular actin assembly.
Acta Crystallogr D Struct Biol, 76, 2020
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7Z6X
 | | Complex of E. coli LolA R43L mutant and lipoprotein | | Descriptor: | Outer-membrane lipoprotein carrier protein, [(2~{S})-3-[(2~{S})-3-azanyl-2-(hexadecanoylamino)-3-oxidanylidene-propyl]sulfanyl-2-hexadecanoyloxy-propyl] hexadecanoate | | Authors: | Kaplan, E, Greene, N.P, Koronakis, V. | | Deposit date: | 2022-03-14 | | Release date: | 2022-09-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structural basis of lipoprotein recognition by the bacterial Lol trafficking chaperone LolA.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z6W
 | | Complex of E. coli LolA and lipoprotein | | Descriptor: | Outer-membrane lipoprotein carrier protein, [(2~{S})-3-[(2~{S})-3-azanyl-2-(hexadecanoylamino)-3-oxidanylidene-propyl]sulfanyl-2-hexadecanoyloxy-propyl] hexadecanoate | | Authors: | Kaplan, E, Greene, N.P, Koronakis, V. | | Deposit date: | 2022-03-14 | | Release date: | 2022-09-07 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Structural basis of lipoprotein recognition by the bacterial Lol trafficking chaperone LolA.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6F3Z
 | | Complex of E. coli LolA and periplasmic domain of LolC | | Descriptor: | Lipoprotein-releasing system transmembrane protein LolC, Outer-membrane lipoprotein carrier protein | | Authors: | Kaplan, E. | | Deposit date: | 2017-11-29 | | Release date: | 2018-07-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Insights into bacterial lipoprotein trafficking from a structure of LolA bound to the LolC periplasmic domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6F49
 | | Periplasmic domain of LolC lacking the Hook. | | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, GLYCEROL, Lipoprotein-releasing system transmembrane protein LolC,Lipoprotein-releasing system transmembrane protein LolC | | Authors: | Kaplan, E. | | Deposit date: | 2017-11-29 | | Release date: | 2018-07-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Insights into bacterial lipoprotein trafficking from a structure of LolA bound to the LolC periplasmic domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6FHM
 | | Crystal structure of the F47E mutant of the lipoprotein localization factor, LolA | | Descriptor: | GLYCEROL, Outer-membrane lipoprotein carrier protein | | Authors: | Kaplan, E, Greene, N.P, Crow, A, Koronakis, V. | | Deposit date: | 2018-01-15 | | Release date: | 2018-07-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Insights into bacterial lipoprotein trafficking from a structure of LolA bound to the LolC periplasmic domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5NAA
 | | Lipoprotein-releasing system transmembrane protein LolC | | Descriptor: | Lipoprotein-releasing system transmembrane protein LolC, SULFATE ION | | Authors: | Kaplan, E. | | Deposit date: | 2017-02-27 | | Release date: | 2017-11-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4N57
 | | Crystal structure of aminoglycoside phosphotransferase APH(2'')-IVa ADP complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, APH(2'')-Id, MAGNESIUM ION | | Authors: | Kaplan, E, Leban, N, Chaloin, L, Guichou, J.-F, Lionne, C. | | Deposit date: | 2013-10-09 | | Release date: | 2014-12-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of aminoglycoside phosphotransferase APH(2'')-IVa ADP complex
To be Published
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5C4L
 | | Conformational alternate of sisomicin in complex with APH(2")-IVa | | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, (2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-ol, APH(2'')-Id | | Authors: | Kaplan, E, Guichou, J.F, Berrou, K, Chaloin, L, Leban, N, Lallemand, P, Barman, T, Serpersu, E.H, Lionne, C. | | Deposit date: | 2015-06-18 | | Release date: | 2016-02-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Aminoglycoside binding and catalysis specificity of aminoglycoside 2-phosphotransferase IVa: A thermodynamic, structural and kinetic study.
Biochim.Biophys.Acta, 1860, 2016
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5C4K
 | | APH(2")-IVa in complex with GET (G418) at room temperature | | Descriptor: | APH(2'')-Id, GENETICIN | | Authors: | Kaplan, E, Guichou, J.F, Berrou, K, Chaloin, L, Leban, N, Lallemand, P, Barman, T, Serpersu, E.H, Lionne, C. | | Deposit date: | 2015-06-18 | | Release date: | 2016-02-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Aminoglycoside binding and catalysis specificity of aminoglycoside 2-phosphotransferase IVa: A thermodynamic, structural and kinetic study.
Biochim.Biophys.Acta, 1860, 2016
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4N9Q
 | | Crystal structure of paAzoR1 bound to ubiquinone-1 | | Descriptor: | FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 1, GLYCEROL, ... | | Authors: | Ryan, A, Kaplan, E, Crescente, V, Lowe, E, Preston, G.M, Sim, E. | | Deposit date: | 2013-10-21 | | Release date: | 2014-06-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Superfamily of Enzymes.
Plos One, 9, 2014
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8QOE
 | | Inward-facing conformation of the ABC transporter BmrA | | Descriptor: | Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | | Authors: | Di Cesare, M, Kaplan, E, Valimehr, S, Hanssen, E, Orelle, C, Jault, J.M. | | Deposit date: | 2023-09-28 | | Release date: | 2023-12-20 | | Last modified: | 2024-01-24 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
J.Biol.Chem., 300, 2023
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8CHB
 | | Inward-facing conformation of the ABC transporter BmrA C436S/A582C cross-linked mutant | | Descriptor: | Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | | Authors: | Di Cesare, M, Kaplan, E, Hanssen, E, Valimehr, S, Orelle, C, Jault, J.M. | | Deposit date: | 2023-02-07 | | Release date: | 2023-12-20 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
J.Biol.Chem., 300, 2023
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4N65
 | | Crystal structure of paAzoR1 bound to anthraquinone-2-sulphonate | | Descriptor: | 9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 1, ... | | Authors: | Ryan, A, Kaplan, E, Crescente, V, Lowe, E, Preston, G.M, Sim, E. | | Deposit date: | 2013-10-11 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.816 Å) | | Cite: | Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Superfamily of Enzymes.
Plos One, 9, 2014
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