3A79
 
 | | Crystal structure of TLR2-TLR6-Pam2CSK4 complex | | 分子名称: | (2S)-propane-1,2-diyl dihexadecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kang, J.Y, Jin, M.S, Lee, J.-O. | | 登録日 | 2009-09-20 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009
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3A7C
 | | Crystal structure of TLR2-PE-DTPA complex | | 分子名称: | (10S,13R)-3-{2-[{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-10-hydroxy-5,16-dioxo-13-(tetradecanoyloxy)-9,11,15-trioxa-3,6-diaza-10-phosphanonacosan-1-oic acid 10-oxide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kang, J.Y, Jin, M.S, Lee, J.-O. | | 登録日 | 2009-09-20 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009
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3A7B
 | | Crystal structure of TLR2-Streptococcus Pneumoniae lipoteichoic acid complex | | 分子名称: | (2S)-1-({3-O-[2-(acetylamino)-4-amino-2,4,6-trideoxy-beta-D-galactopyranosyl]-alpha-D-glucopyranosyl}oxy)-3-(heptanoyloxy)propan-2-yl (7Z)-pentadec-7-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kang, J.Y, Jin, M.S, Lee, J.-O. | | 登録日 | 2009-09-20 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Immunity, 31, 2009
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8EG8
 | | Cryo-EM structure of consensus elemental paused elongation complex with a folded TL | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-12 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EGB
 | | Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-12 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EG7
 | | Cryo-EM structure of pre-consensus elemental paused elongation complex | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-11 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHI
 | | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (2) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-14 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHF
 | | Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1) | | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-14 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EHA
 | | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-14 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EH8
 | | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (1) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-13 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8EH9
 | | Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (2) | | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | | 登録日 | 2022-09-13 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6ALG
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6BJS
 | | CryoEM structure of E.coli his pause elongation complex without pause hairpin | | 分子名称: | DNA (32-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Landick, R, Darst, S.A. | | 登録日 | 2017-11-06 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing.
Mol. Cell, 69, 2018
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6C6S
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound with RfaH | | 分子名称: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A. | | 登録日 | 2018-01-19 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.
Cell, 173, 2018
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6ASX
 | | CryoEM structure of E.coli his pause elongation complex | | 分子名称: | DNA (32-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Landick, R, Darst, S.A. | | 登録日 | 2017-08-25 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing.
Mol. Cell, 69, 2018
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6C6U
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound with NusG | | 分子名称: | DNA (29-MER), DNA-DIRECTED RNA POLYMERASE BETA', DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A. | | 登録日 | 2018-01-19 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.
Cell, 173, 2018
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6ALF
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6C6T
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound with RfaH | | 分子名称: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A. | | 登録日 | 2018-01-19 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.
Cell, 173, 2018
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6LIN
 | | Crystal structure of human PDK2 complexed with GM10030 | | 分子名称: | 4-[[[4-[3,5-bis(fluoranyl)-4-(4-oxidanyl-4-oxidanylidene-butoxy)phenyl]-5-[5-chloranyl-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-3-yl]carbonylamino]methyl]benzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Kang, J, Kim, J. | | 登録日 | 2019-12-12 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds.
Biochem.Biophys.Res.Commun., 527, 2020
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6ALH
 | | CryoEM structure of E.coli RNA polymerase elongation complex | | 分子名称: | DNA (29-MER), DNA (5'-D(*GP*GP*GP*CP*TP*AP*AP*TP*GP*AP*CP*GP*GP*CP*GP*AP*AP*TP*AP*CP*CP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Kang, J.Y, Darst, S.A. | | 登録日 | 2017-08-07 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural basis of transcription arrest by coliphage HK022 Nun in anEscherichia coliRNA polymerase elongation complex.
Elife, 6, 2017
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6LIO
 | | Crystal structure of human PDK2 complexed with GM67520 | | 分子名称: | 4-[[[5-[5-chloranyl-2,4-bis(oxidanyl)phenyl]-4-[4-(1-methylsulfonylpiperidin-4-yl)oxyphenyl]-1,2-oxazol-3-yl]carbonylamino]methyl]cyclohexane-1-carboxylic acid, GLYCEROL, SULFATE ION, ... | | 著者 | Kang, J, Kim, J. | | 登録日 | 2019-12-12 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds.
Biochem.Biophys.Res.Commun., 527, 2020
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6LIL
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5BZ6
 | | Crystal structure of the N-terminal domain single mutant (S92A) of the human mitochondrial calcium uniporter fused with T4 lysozyme | | 分子名称: | Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION | | 著者 | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | | 登録日 | 2015-06-11 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
Embo Rep., 16, 2015
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5CJ9
 | | Bacillus halodurans Arginine repressor, ArgR | | 分子名称: | Arginine repressor, S-1,2-PROPANEDIOL | | 著者 | Park, Y.W, Kang, J, Yeo, H.Y, Lee, J.Y. | | 登録日 | 2015-07-14 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.409 Å) | | 主引用文献 | Structural Analysis and Insights into the Oligomeric State of an Arginine-Dependent Transcriptional Regulator from Bacillus halodurans.
Plos One, 11, 2016
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6J10
 | | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | | 分子名称: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | | 著者 | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | | 登録日 | 2018-12-27 | | 公開日 | 2019-04-17 | | 最終更新日 | 2019-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly.
Nat Commun, 10, 2019
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