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PDB: 4 件

4OHF
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BU of 4ohf by Molmil
Crystal structure of cytosolic nucleotidase II (LPG0095) in complex with GMP from Legionella pneumophila, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LGR1
分子名称: Cytosolic IMP-GMP specific 5'-nucleotidase, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ...
著者Srinivisan, B, Forouhar, F, Shukla, A, Sampangi, C, Kulkarni, S, Abashidze, M, Seetharaman, J, Lew, S, Mao, L, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.M, Tong, L, Balaram, H, Northeast Structural Genomics Consortium (NESG)
登録日2014-01-17
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.
Febs J., 281, 2014
8JZA
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BU of 8jza by Molmil
Crystal structure of single domain antibody kt75 of human Thyroglobulin
分子名称: ACETATE ION, POTASSIUM ION, single domain antibody kt75 of human Thyroglobulin
著者Mistry, H, Kumarasamy, J, Kumari, S, Kulkarni, S.P, Gupta, G.D.
登録日2023-07-04
公開日2024-07-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal structure of single domain antibody kt75 of human Thyroglobulin
To Be Published
8E90
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BU of 8e90 by Molmil
Inhibition of Human Menin by SNDX-5613
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, ...
著者McKeever, B.M, KULKARNI, S, McGeehan, G.M.
登録日2022-08-26
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献MEN1 mutations mediate clinical resistance to menin inhibition.
Nature, 615, 2023
7UJ4
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BU of 7uj4 by Molmil
Inhibition of Human Menin by SNDX-5613
分子名称: 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, Isoform 2 of Menin, MAGNESIUM ION
著者McKeever, B.M, Kulkarni, S, McGeehan, G.M.
登録日2022-03-30
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献MEN1 mutations mediate clinical resistance to menin inhibition.
Nature, 615, 2023

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件を2024-11-06に公開中

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