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PDB: 36 件

3ZGF
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Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with in complex with NPE caged UDP-Gal (P2(1)2(1)2(1) space group)
分子名称: 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, MANGANESE (II) ION, ...
著者Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M.
登録日2012-12-17
公開日2013-01-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Acta Crystallogr.,Sect.F, 70, 2014
3ZGG
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Crystal structure of the Fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with NPE caged UDP-Gal (C222(1) space group)
分子名称: 1-(2-NITROPHENYL)ETHYL UDP-GALACTOSE, GLYCEROL, HISTO-BLOOD GROUP ABO SYSTEM TRANSFERASE, ...
著者Jorgensen, R, Batot, G.O, Hindsgaul, O, Tanaka, H, Perez, S, Imberty, A, Breton, C, Royant, A, Palcic, M.M.
登録日2012-12-17
公開日2014-01-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of a Human Blood Group Glycosyltransferase in Complex with a Photo-Activatable Udp-Gal Derivative Reveal Two Different Binding Conformations
Acta Crystallogr.,Sect.F, 70, 2014
2Q5T
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Full-length Cholix toxin from Vibrio Cholerae
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cholix toxin
著者Jorgensen, R, Fieldhouse, R.J, Merrill, A.R.
登録日2007-06-01
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae.
J.Biol.Chem., 283, 2008
1U2R
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Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jorgensen, R, Yates, S.P, Nilsson, J, Prentice, G.A, Teal, D.J, Merrill, A.R, Andersen, G.R.
登録日2004-07-20
公開日2004-09-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
4X2E
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Clostridium difficile wild type Fic protein
分子名称: Fic family protein putative filamentation induced by cAMP protein
著者Jorgensen, R, Dedic, E.
登録日2014-11-26
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Structure of wild type Clostridium difficile Fic_0569 at 3.1 Angstroms resolution
To Be Published
4X2C
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Clostridium difficile Fic protein_0569 mutant S31A, E35A
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fic family protein putative filamentation induced by cAMP protein, GLYCEROL, ...
著者Jorgensen, R, Dedic, E.
登録日2014-11-26
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Clostridium difficile Fic_0569 S31A, E35A mutant at 1.8 Angstroms resolution
To Be Published
4X2D
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Clostridium difficile Fic protein_0569 mutant S31A, E35A in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Fic family protein putative filamentation induced by cAMP protein, MAGNESIUM ION
著者Jorgensen, R, Dedic, E.
登録日2014-11-26
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Clostridium difficile Fic_0569 S31A, E35A mutant at 1.8 Angstroms resolution
To Be Published
2ZIT
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Structure of the eEF2-ExoA-NAD+ complex
分子名称: Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Jorgensen, R, Merrill, A.R.
登録日2008-02-24
公開日2008-06-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The nature and character of the transition state for the ADP-ribosyltransferase reaction.
Embo Rep., 9, 2008
3B78
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Structure of the eEF2-ExoA(R551H)-NAD+ complex
分子名称: Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Jorgensen, R, Merrill, A.R.
登録日2007-10-30
公開日2008-06-17
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The nature and character of the transition state for the ADP-ribosyltransferase reaction.
Embo Rep., 9, 2008
3B82
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Structure of the eEF2-ExoA(E546H)-NAD+ complex
分子名称: Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Jorgensen, R, Merrill, A.R.
登録日2007-10-31
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The nature and character of the transition state for the ADP-ribosyltransferase reaction.
Embo Rep., 9, 2008
3B8H
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BU of 3b8h by Molmil
Structure of the eEF2-ExoA(E546A)-NAD+ complex
分子名称: Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Jorgensen, R, Merrill, A.R.
登録日2007-11-01
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The nature and character of the transition state for the ADP-ribosyltransferase reaction.
Embo Rep., 9, 2008
3DOJ
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Structure of Glyoxylate reductase 1 from Arabidopsis (AtGLYR1)
分子名称: CHLORIDE ION, Dehydrogenase-like protein
著者Jorgensen, R.
登録日2008-07-04
公開日2009-07-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Cytosolic NADPH-dependent Glyoxylate Reductase from Arabidopsis: Crystal Structure and Kinetic Characterization of Active Site Mutants
To be Published
3KI0
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-D
分子名称: 3-(morpholin-4-ylmethyl)-1,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one, CHLORIDE ION, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KI7
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-I
分子名称: 2-{2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl}-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KI2
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-G
分子名称: 2-(4-methylpiperazin-1-yl)benzo[c][1,5]naphthyridin-6(5H)-one, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KI4
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BU of 3ki4 by Molmil
Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-P
分子名称: (11bR)-3-oxo-1,2,3,11b-tetrahydrochromeno[4,3,2-de]isoquinoline-10-sulfonic acid, Cholix toxin, GLYCEROL
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KI6
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-L
分子名称: 8-fluoro-2-(3-piperidin-1-ylpropanoyl)-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-6(2H)-one, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KI3
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-H
分子名称: 2-[(dimethylamino)methyl]-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KI5
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-M
分子名称: Cholix toxin, N-(6-oxo-5,6-dihydrobenzo[c][1,5]naphthyridin-2-yl)-2-(4-pyrrolidin-1-ylpiperidin-1-yl)acetamide
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3KI1
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with inhibitor GP-F
分子名称: 2-{4-[3-(dimethylamino)propoxy]phenyl}-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one, Cholix toxin
著者Jorgensen, R, Edwards, P.R, Merrill, A.R.
登録日2009-10-31
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
To be Published
3ESS
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BU of 3ess by Molmil
Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with the 1,8-Naphthalimide inhibitor
分子名称: 1H-benzo[de]isoquinoline-1,3(2H)-dione, Cholix toxin
著者Merrill, A.R, Jorgensen, R.
登録日2008-10-06
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.191 Å)
主引用文献Yeast as a tool for characterizing mono-ADP-ribosyltransferase toxins
Fems Microbiol.Lett., 300, 2009
4V4B
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BU of 4v4b by Molmil
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
著者Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
登録日2004-01-06
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
3Q9O
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Full-length Cholix toxin from Vibrio cholerae in complex with NAD
分子名称: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, exotoxin A
著者Merrill, A.R, Jorgensen, R, Fieldhouse, R.J.
登録日2011-01-09
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献The 1.8 a cholix toxin crystal structure in complex with NAD+ and evidence for a new kinetic model.
J.Biol.Chem., 287, 2012
2Q6M
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Catalytic fragment of Cholix toxin from Vibrio Cholerae in complex with the PJ34 inhibitor
分子名称: Cholix toxin, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
著者Merrill, A.R, Jorgensen, R.
登録日2007-06-05
公開日2008-02-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Cholix Toxin, a Novel ADP-ribosylating Factor from Vibrio cholerae.
J.Biol.Chem., 283, 2008
3IOH
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Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A)
分子名称: GLYCEROL, Histo-blood group ABO system transferase
著者Pesnot, T, Jorgensen, R, Palcic, M.M, Wagner, G.K.
登録日2009-08-14
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural and mechanistic basis for a new mode of glycosyltransferase inhibition.
Nat.Chem.Biol., 6, 2010

 

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