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PDB: 7 件
5T14
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BU of 5t14 by Molmil
DNA polymerase kappa extending beyond a bulky major benzo[a]pyrene adduct
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA, DNA polymerase kappa, ...
著者Jha, V.K, Ling, H.
登録日2016-08-17
公開日2016-12-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of accurate replication beyond a bulky major benzo[a]pyrene adduct by human DNA polymerase kappa.
DNA Repair (Amst.), 49, 2017
6BRX
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BU of 6brx by Molmil
Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DI(HYDROXYETHYL)ETHER, ...
著者Jha, V.K, Ling, H.
登録日2017-12-01
公開日2018-08-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender.
J. Mol. Biol., 430, 2018
6BS1
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BU of 6bs1 by Molmil
Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*TP*AP*CP*TP*GP*GP*TP*AP*TP*GP*TP*AP*T)-3'), ...
著者Jha, V.K, Ling, H.
登録日2017-12-01
公開日2018-08-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender.
J. Mol. Biol., 430, 2018
5W2A
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BU of 5w2a by Molmil
Structure of human DNA polymerase kappa in complex with Lucidin-derived DNA adduct and incoming dCMPNPP
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*TP*GP*(LDG)P*CP*TP*GP*AP*TP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*G)-3'), ...
著者Jha, V.K, Ling, H.
登録日2017-06-06
公開日2017-10-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase kappa.
Chem. Res. Toxicol., 30, 2017
5W2C
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BU of 5w2c by Molmil
Structure of human DNA polymerase kappa in complex with Lucidin-derived DNA adduct and incoming dAMPNPP
分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DI(HYDROXYETHYL)ETHER, ...
著者Jha, V.K, Ling, H.
登録日2017-06-06
公開日2017-10-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase kappa.
Chem. Res. Toxicol., 30, 2017
4U6P
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BU of 4u6p by Molmil
Structural mechanism of error-free bypass of major benzo[a]pyrene adduct by human polymerase kappa
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*TP*AP*TP*GP*GP*TP*GP*AP*TP*CP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*GP*AP*TP*CP*AP*C)-3'), ...
著者Jha, V.K, Ling, H.
登録日2014-07-29
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.593 Å)
主引用文献Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase kappa.
Nucleic Acids Res., 44, 2016
4U7C
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BU of 4u7c by Molmil
Structure of DNA polymerase kappa in complex with benzopyrene adducted DNA
分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DI(HYDROXYETHYL)ETHER, ...
著者Jha, V.K, Ling, H.
登録日2014-07-30
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase kappa.
Nucleic Acids Res., 44, 2016

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件を2024-07-24に公開中

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